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Clinical decision-making in oncology involves multimodal data such as radiology scans, molecular profiling, histopathology slides, and clinical factors. Despite the importance of these modalities individually, no deep learning framework to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Nathaniel Braman , Jacob W. H. Gordon , Emery T. Goossens , Caleb Willis , Martin C. Stumpe , Jagadish Venkataraman

Federated learning (FL) for histopathology image segmentation involving multiple medical sites plays a crucial role in advancing the field of accurate disease diagnosis and treatment. However, it is still a task of great challenges due to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Lotfi Senhadji , Yongyue Wei , Feng Chen , Guanyu Yang

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

Melanoma is an aggressive form of skin cancer with rapid progression and high metastatic potential. Accurate characterisation of tissue morphology in melanoma is crucial for prognosis and treatment planning. However, manual segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-21 Jiaqi Lv , Yijie Zhu , Carmen Guadalupe Colin Tenorio , Brinder Singh Chohan , Mark Eastwood , Shan E Ahmed Raza

Existing few-shot medical image segmentation (FSMIS) models fail to address a practical issue in medical imaging: the domain shift caused by different imaging techniques, which limits the applicability to current FSMIS tasks. To overcome…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Yuntian Bo , Yazhou Zhu , Lunbo Li , Haofeng Zhang

Objective: To report imaging protocol and scheduling variance in routine care of glioblastoma patients in order to demonstrate challenges of integrating deep-learning models in glioblastoma care pathways. Additionally, to understand the…

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Purpose: Bone metastasis have a major impact on the quality of life of patients and they are diverse in terms of size and location, making their segmentation complex. Manual segmentation is time-consuming, and expert segmentations are…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Emile Saillard , Aurélie Levillain , David Mitton , Jean-Baptiste Pialat , Cyrille Confavreux , Hélène Follet , Thomas Grenier

Large pre-trained models with their numerous model parameters and extensive training datasets have shown excellent performance in various tasks. Many publicly available medical image datasets do not have a sufficient amount of data so there…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Jianhao Xie , Ziang Zhang , Guibo Luo , Yuesheng Zhu

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Tumor segmentation in multimodal medical images has seen a growing trend towards deep learning based methods. Typically, studies dealing with this topic fuse multimodal image data to improve the tumor segmentation contour for a single…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Theresa Neubauer , Maria Wimmer , Astrid Berg , David Major , Dimitrios Lenis , Thomas Beyer , Jelena Saponjski , Katja Bühler

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Tooth segmentation is a critical technology in the field of medical image segmentation, with applications ranging from orthodontic treatment to human body identification and dental pathology assessment. Despite the development of numerous…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Dongping Zhang , Zheng Li , Fangao Zeng , Yutong Wei

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Automated polyp segmentation is essential for early diagnosis of colorectal cancer, yet developing robust models remains challenging due to limited annotated data and significant performance degradation under domain shift. Although…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Haoran Xi , Chen Liu , Xiaolin Li

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Accurate diagnosis of glaucoma is challenging, as early-stage changes are subtle and often lack clear structural or appearance cues. Most existing approaches rely on a single modality, such as fundus or optical coherence tomography (OCT),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhiwei Wang , Yuxing Li , Meilu Zhu , Defeng He , Edmund Y. Lam