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Osteosarcoma is the most common primary bone cancer, mainly affecting the youngest and oldest populations. Its detection at early stages is crucial to reduce the probability of developing bone metastasis. In this context, accurate and fast…

In the U.S, 5-10\% of new pediatric cases of cancer are primary bone tumors. The most common type of primary malignant bone tumor is osteosarcoma. The intention of the present work is to improve the detection and diagnosis of osteosarcoma…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 D M Anisuzzaman , Hosein Barzekar , Ling Tong , Jake Luo , Zeyun Yu

Osteosarcoma is the most common primary malignant bone tumor, which has high mortality due to easy lung metastasis. Osteosarcoma is a highly anaplastic, pleomorphic tumor with a variety of tumor cell morphology, including fusiform, oval,…

Medical Physics · Physics 2021-01-27 Yu Fu

Osteosarcoma is the most common primary bone cancer whose standard treatment includes pre-operative chemotherapy followed by resection. Chemotherapy response is used for predicting prognosis and further management of patients. Necrosis is…

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Tian Lan , Lei Xu , Zimu Yuan , Shanggui Liu , Jiajun Liu , Jiaxin Liu , Weilai Xiang , Hongyu Yang , Dong Jiang , Jianxin Yin , Dingyu Wang

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Skin diseases affect millions of people worldwide, across all ethnicities. Increasing diagnosis accessibility requires fair and accurate segmentation and classification of dermatology images. However, the scarcity of annotated medical…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Héctor Carrión , Narges Norouzi

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

Denoising Diffusion Models (DDMs) are widely used for high-quality image generation and medical image segmentation but often rely on Unet-based architectures, leading to high computational overhead, especially with high-resolution images.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Avni Mittal , John Kalkhof , Anirban Mukhopadhyay , Arnav Bhavsar

The degree of malignancy of osteosarcoma and its tendency to metastasize/spread mainly depend on the pathological grade (determined by observing the morphology of the tumor under a microscope). The purpose of this study is to use artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-02 Liangrui Pan , Hetian Wang , Lian Wang , Boya Ji , Mingting Liu , Mitchai Chongcheawchamnan , Jin Yuan , Shaoliang Peng

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

Skin lesion segmentation plays a critical role in the early detection and accurate diagnosis of dermatological conditions. Denoising Diffusion Probabilistic Models (DDPMs) have recently gained attention for their exceptional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Afshin Bozorgpour , Yousef Sadegheih , Amirhossein Kazerouni , Reza Azad , Dorit Merhof

We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling…

Logic in Computer Science · Computer Science 2011-11-10 Pietro Liò , Emanuela Merelli , Nicola Paoletti

Early diagnosis of cancer often allows for a more vast choice of therapy opportunities. After a cancer diagnosis, staging provides essential information about the extent of disease in the body and the expected response to a particular…

Computer Vision and Pattern Recognition · Computer Science 2020-08-06 Mario D'Acunto , Massimo Martinelli , Davide Moroni

In medical imaging, unsupervised out-of-distribution (OOD) detection offers an attractive approach for identifying pathological cases with extremely low incidence rates. In contrast to supervised methods, OOD-based approaches function…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lemar Abdi , Francisco Caetano , Amaan Valiuddin , Christiaan Viviers , Hamdi Joudeh , Fons van der Sommen

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

The Diffusion Probabilistic Model (DPM) has demonstrated remarkable performance across a variety of generative tasks. The inherent randomness in diffusion models helps address issues such as blurring at the edges of medical images and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Yilong Hu , Shijie Chang , Lihe Zhang , Feng Tian , Weibing Sun , Huchuan Lu

Medical image segmentation is a critical component in clinical practice, facilitating accurate diagnosis, treatment planning, and disease monitoring. However, existing methods, often tailored to specific modalities or disease types, lack…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Jun Ma , Yuting He , Feifei Li , Lin Han , Chenyu You , Bo Wang
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