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Modeling correlated or highly stratified multiple-response data becomes a common data analysis task due to modern data monitoring facilities and methods. Generalized estimating equations (GEE) is one of the popular statistical methods for…

Methodology · Statistics 2019-03-05 Zimu Chen , Zhanfeng Wang , Yuan-chin Ivan Chang

The association between multidimensional exposure patterns and outcomes is commonly investigated by first applying cluster analysis algorithms to derive patterns and then estimating the associations. However, errors in the underlying…

Methodology · Statistics 2023-05-31 Timm Intemann , Iris Pigeot

Training the parameters of statistical models to describe a given data set is a central task in the field of data mining and machine learning. A very popular and powerful way of parameter estimation is the method of maximum likelihood…

Machine Learning · Computer Science 2016-03-22 Johannes Blömer , Sascha Brauer , Kathrin Bujna

Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

In large-scale epidemiological studies, statistical inference is often complicated by high-dimensional covariates under stratified sampling designs for failure times. Variable selection methods developed for full cohort data do not extend…

Methodology · Statistics 2025-07-22 Ying Chen , Chuan-Fa Tang , Sy Han Chiou , Min Chen

Bayesian analysis is increasingly popular for use in social science and other application areas where the data are observations from an informative sample. An informative sampling design leads to inclusion probabilities that are correlated…

Statistics Theory · Mathematics 2016-06-07 Terrance D. Savitsky , Daniell Toth

Penalized generalized estimating equations (PGEE) stabilize point estimation for longitudinal binary data under near-separation, but inference still depends on how the sandwich variance is corrected. Existing corrections for PGEE can…

Methodology · Statistics 2026-04-22 Awan Afiaz , M. Shafiqur Rahman

Longitudinal binary or count functional data are common in neuroscience, but are often too large to analyze with existing functional regression methods. We propose one-step penalized generalized estimating equations that supports…

Methodology · Statistics 2026-03-31 Gabriel Loewinger , Alex W. Levis , Erjia Cui , Francisco Pereira

Information theoretic criteria (ITC) have been widely adopted in engineering and statistics for selecting, among an ordered set of candidate models, the one that better fits the observed sample data. The selected model minimizes a penalized…

Machine Learning · Statistics 2019-10-10 Andrea Mariani , Andrea Giorgetti , Marco Chiani

Determining how to appropriately select the tuning parameter is essential in penalized likelihood methods for high-dimensional data analysis. We examine this problem in the setting of penalized likelihood methods for generalized linear…

Methodology · Statistics 2016-05-12 Yingying Fan , Cheng Yong Tang

Generalized estimating equations (GEE) are widely used to analyze longitudinal data; however, they are not appropriate for heteroscedastic data, because they only estimate regressor effects on the mean response{\textemdash}and therefore do…

Methodology · Statistics 2020-12-29 Amadou Barry , Karim Oualkacha , Arthur Charpentier

Standard random-effects meta-analysis relies heavily on the assumption that the underlying true effects are normally distributed. In the social sciences, where evidence synthesis increasingly involves large, highly heterogeneous datasets,…

Methodology · Statistics 2026-05-01 Daihe Sui , Elizabeth Tipton

Loss-based clustering methods, such as k-means and its variants, are standard tools for finding groups in data. However, the lack of quantification of uncertainty in the estimated clusters is a disadvantage. Model-based clustering based on…

Methodology · Statistics 2020-06-11 Tommaso Rigon , Amy H. Herring , David B. Dunson

In this paper, we present a generalized estimating equations based estimation approach and a variable selection procedure for single-index models when the observed data are clustered. Unlike the case of independent observations,…

Methodology · Statistics 2011-08-08 Peng Lai , Qihua Wang , Heng Lian

Variable selection in cluster analysis is important yet challenging. It can be achieved by regularization methods, which realize a trade-off between the clustering accuracy and the number of selected variables by using a lasso-type penalty.…

Methodology · Statistics 2016-12-23 Marbac Matthieu , Sedki Mohammed

Survey data are often collected under multistage sampling designs where units are binned to clusters that are sampled in a first stage. The unit-indexed population variables of interest are typically dependent within cluster. We propose a…

Methodology · Statistics 2021-08-26 Luis G. Leon-Novelo , Terrance D. Savitsky

Popular statistical software provides Bayesian information criterion (BIC) for multilevel models or linear mixed models. However, it has been observed that the combination of statistical literature and software documentation has led to…

Methodology · Statistics 2022-06-24 Sun-Joo Cho , Hao Wu , Matthew Naveiras

The Generalized Estimating Equations (GEE) approach is a widely used statistical method for analyzing longitudinal data and clustered data in clinic studies. In dentistry, due to multiple outcomes obtained from one patient, the outcomes…

Methodology · Statistics 2025-02-25 Hoi-Jeong Lim , Soo-Hyeon Park

This study introduces a general semiparametric clusterwise index distribution model to analyze how latent clusters affect the covariate-response relationships. By employing sufficient dimension reduction to account for the effects of…

Methodology · Statistics 2025-09-30 Jen-Chieh Teng , Chin-Tsang Chiang

We discuss the problem of estimating the number of principal components in Principal Com- ponents Analysis (PCA). Despite of the importance of the problem and the multitude of solutions proposed in the literature, it comes as a surprise…

Methodology · Statistics 2016-07-06 Piotr Sobczyk , Malgorzata Bogdan , Julie Josse