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Background: The potential of large language models (LLMs) to automate and support pharmacoepidemiologic study design is an emerging area of interest, yet their reliability remains insufficiently characterized. General-purpose LLMs often…

Computation and Language · Computer Science 2026-04-21 Xinyao Zhang , Nicole Sonne Heckmann , Manuela Del Castillo Suero , Francesco Paolo Speca , Maurizio Sessa

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Large Language Models (LLMs) have revolutionized the field of Natural Language Processing thanks to their ability to reuse knowledge acquired on massive text corpora on a wide variety of downstream tasks, with minimal (if any) tuning steps.…

Computation and Language · Computer Science 2024-07-12 Flavio Petruzzellis , Alberto Testolin , Alessandro Sperduti

Cognitive psychology delves on understanding perception, attention, memory, language, problem-solving, decision-making, and reasoning. Large language models (LLMs) are emerging as potent tools increasingly capable of performing human-level…

Computation and Language · Computer Science 2023-04-13 Sifatkaur Dhingra , Manmeet Singh , Vaisakh SB , Neetiraj Malviya , Sukhpal Singh Gill

This case study investigates the task of job classification in a real-world setting, where the goal is to determine whether an English-language job posting is appropriate for a graduate or entry-level position. We explore multiple…

Computation and Language · Computer Science 2023-04-19 Benjamin Clavié , Alexandru Ciceu , Frederick Naylor , Guillaume Soulié , Thomas Brightwell

The recent swift development of LLMs like GPT-4, Gemini, and GPT-3.5 offers a transformative opportunity in medicine and healthcare, especially in digital diagnostics. This study evaluates each model diagnostic abilities by interpreting a…

Computation and Language · Computer Science 2024-05-14 Gaurav Kumar Gupta , Aditi Singh , Sijo Valayakkad Manikandan , Abul Ehtesham

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

The lack of explainability using relevant clinical knowledge hinders the adoption of Artificial Intelligence-powered analysis of unstructured clinical dialogue. A wealth of relevant, untapped Mental Health (MH) data is available in online…

Artificial Intelligence · Computer Science 2024-10-21 Sumit Dalal , Deepa Tilwani , Kaushik Roy , Manas Gaur , Sarika Jain , Valerie Shalin , Amit Sheth

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

In recent years, groundbreaking advancements in natural language processing have culminated in the emergence of powerful large language models (LLMs), which have showcased remarkable capabilities across a vast array of domains, including…

Computation and Language · Computer Science 2023-12-11 Microsoft Research AI4Science , Microsoft Azure Quantum

This study compares the efficacy of GPT-4 and clinalytix Medical AI in predicting the clinical risk of delirium development. Findings indicate that GPT-4 exhibited significant deficiencies in identifying positive cases and struggled to…

Computation and Language · Computer Science 2024-09-17 Mohamed Rezk , Patricia Cabanillas Silva , Fried-Michael Dahlweid

Digital screening and monitoring applications can aid providers in the management of behavioral health conditions. We explore deep language models for detecting depression, anxiety, and their co-occurrence from conversational speech…

Computation and Language · Computer Science 2024-12-31 Tomasz Rutowski , Elizabeth Shriberg , Amir Harati , Yang Lu , Piotr Chlebek , Ricardo Oliveira

Depression is a global health concern with a critical need for increased patient screening. Speech technology offers advantages for remote screening but must perform robustly across patients. We have described two deep learning models…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Y. Lu , A. Harati , T. Rutowski , R. Oliveira , P. Chlebek , E. Shriberg

With the rise of foundation models, a new artificial intelligence paradigm has emerged, by simply using general purpose foundation models with prompting to solve problems instead of training a separate machine learning model for each…

Artificial Intelligence · Computer Science 2023-08-29 Mostafa M. Amin , Rui Mao , Erik Cambria , Björn W. Schuller

This study examines the effect of prompt engineering on the performance of Large Language Models (LLMs) in clinical note generation. We introduce an Automatic Prompt Optimization (APO) framework to refine initial prompts and compare the…

Computation and Language · Computer Science 2024-07-08 Zonghai Yao , Ahmed Jaafar , Beining Wang , Zhichao Yang , Hong Yu

The rapid evolution of LLMs represents an impactful paradigm shift in digital interaction and content engagement. While they encode vast amounts of human-generated knowledge and excel in processing diverse data types, they often face the…

Human-Computer Interaction · Computer Science 2024-11-20 Anna Bodonhelyi , Efe Bozkir , Shuo Yang , Enkelejda Kasneci , Gjergji Kasneci

Recent investigations show that large language models (LLMs), specifically GPT-4, not only have remarkable capabilities in common Natural Language Processing (NLP) tasks but also exhibit human-level performance on various professional and…

Computation and Language · Computer Science 2023-06-05 Zhuo Wang , Rongzhen Li , Bowen Dong , Jie Wang , Xiuxing Li , Ning Liu , Chenhui Mao , Wei Zhang , Liling Dong , Jing Gao , Jianyong Wang

Post-Traumatic Stress Disorder (PTSD) remains underdiagnosed in clinical settings, presenting opportunities for automated detection to identify patients. This study evaluates natural language processing approaches for detecting PTSD from…

Computation and Language · Computer Science 2026-01-08 Feng Chen , Dror Ben-Zeev , Gillian Sparks , Arya Kadakia , Trevor Cohen

Large language models (LLMs) are playing an increasingly important role in science and engineering. For example, their ability to parse and understand human and computer languages makes them powerful interpreters and their use in…

Materials Science · Physics 2023-10-19 Juan C. Verduzco , Ethan Holbrook , Alejandro Strachan

Traditional Korean medicine (TKM) emphasizes individualized diagnosis and treatment. This uniqueness makes AI modeling difficult due to limited data and implicit processes. Large language models (LLMs) have demonstrated impressive medical…

Computation and Language · Computer Science 2023-12-19 Dongyeop Jang , Tae-Rim Yun , Choong-Yeol Lee , Young-Kyu Kwon , Chang-Eop Kim