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Spike timing dependent plasticity (STDP) is believed to play an important role in shaping the structure of neural circuits. Here we show that STDP generates effective interactions between synapses of different neurons, which were neglected…

Neurons and Cognition · Quantitative Biology 2016-08-25 Neta Ravid Tannenbaum , Yoram Burak

The response time of physical computational elements is finite, and neurons are no exception. In hierarchical models of cortical networks each layer thus introduces a response lag. This inherent property of physical dynamical systems…

Neurons and Cognition · Quantitative Biology 2021-10-28 Paul Haider , Benjamin Ellenberger , Laura Kriener , Jakob Jordan , Walter Senn , Mihai A. Petrovici

High-dimensional chaotic dynamics can emerge in a large random recurrent neural network when the synaptic gain crosses a threshold. Recent works showed that the kinetic energy of neural activity links the chaotic dynamics and the supporting…

Statistical Mechanics · Physics 2026-02-17 Li-Ru Zhang , Haiping Huang

Cellular decision making is based on regulatory circuits that associate signal thresholds to specific physiological actions. This transmission of information is subjected to molecular noise what can decrease its fidelity. Here, we show…

Molecular Networks · Quantitative Biology 2017-02-08 Guillermo Rodrigo , Juan F. Poyatos

Sensory neurons give highly variable responses to stimulation, which can limit the amount of stimulus information available to downstream circuits. Much work has investigated the factors that affect the amount of information encoded in…

Neurons and Cognition · Quantitative Biology 2017-04-20 Joel Zylberberg , Alexandre Pouget , Peter E. Latham , Eric Shea-Brown

To infer information flow in any network of agents, it is important first and foremost to establish causal temporal relations between the nodes. Practical and automated methods that can infer causality are difficult to find, and the subject…

Neural and Evolutionary Computing · Computer Science 2024-12-11 Ali Tehrani-Saleh , Christoph Adami

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

Spontaneous formation of clusters of synchronized spiking in a structureless ensemble of equal stochastically perturbed excitable neurons with delayed coupling is demonstrated for the first time. The effect is a consequence of a subtle…

Adaptation and Self-Organizing Systems · Physics 2015-06-04 Igor Franovic , Kristina Todorovic , Nebojsa Vasovic , Nikola Buric

The fundamental, powerful process of computation in the brain has been widely misunderstood. The paper [1] associates the general failure to build intelligent thinking machines with current reductionist principles of temporal coding and…

Neural and Evolutionary Computing · Computer Science 2012-10-09 Dorian Aur

Neural circuits exhibit structured connectivity, including an overrepresentation of reciprocal connections between neuron pairs. Despite important advances, a full understanding of how such partial symmetry in connectivity shapes neural…

The hallmark of deterministic chaos is that it creates information---the rate being given by the Kolmogorov-Sinai metric entropy. Since its introduction half a century ago, the metric entropy has been used as a unitary quantity to measure a…

Chaotic Dynamics · Physics 2015-06-17 Ryan G. James , Korana Burke , James P. Crutchfield

Synaptic interactions structure the phase space of the dynamics of neural circuits and constrain neural computation. Understanding how requires methods that handle those discrete interactions, yet few exist. Recently, it was discovered that…

Disordered Systems and Neural Networks · Physics 2019-05-15 Maximilian Puelma Touzel , Fred Wolf

Biological circuits such as neural or gene regulation networks use internal states to map sensory input to an adaptive repertoire of behavior. Characterizing this mapping is a major challenge for systems biology, and though experiments that…

Neurons and Cognition · Quantitative Biology 2022-10-12 Edward D. Lee , Xiaowen Chen , Bryan C. Daniels

We undertake a systematic study of the dynamics of Boolean networks to determine the origin of chaos observed in recent experiments. Networks with nodes consisting of ideal logic gates are known to display either steady states, periodic…

Chaotic Dynamics · Physics 2015-05-14 Hugo L. D. de S. Cavalcante , Daniel J. Gauthier , Joshua E. S. Socolar , Rui Zhang

We evoke the idea of representation of the chaotic attractor by the set of unstable periodic orbits and disclose a novel noise-induced ordering phenomenon. For long unstable periodic orbits forming the strange attractor the weights (or…

Chaotic Dynamics · Physics 2014-05-14 Denis S. Goldobin

The brain is composed of complex networks of interacting neurons that express considerable heterogeneity in their physiology and spiking characteristics. How does neural heterogeneity affect macroscopic neural dynamics and how does it…

Neurons and Cognition · Quantitative Biology 2022-06-20 Richard Gast , Sara A. Solla , Ann Kennedy

This work simulates the developmental process of cortical neurogenesis, initiating from a single stem cell and governed by gene regulatory rules derived from mouse single-cell transcriptomic data. The developmental process spontaneously…

Neural and Evolutionary Computing · Computer Science 2026-04-17 Duan Zhou

Cellular biology exists embedded in a world dominated by random dynamics and chance. Many vital molecules and pieces of cellular machinery diffuse within cells, moving along random trajectories as they collide with the other biomolecular…

Cell Behavior · Quantitative Biology 2012-08-13 Iain G. Johnston

We disclose a new class of patterns, called patched patterns, in arrays of non-locally coupled excitable units with attractive and repulsive interactions. Self-organization process involves formation of two types of patches, majority and…

Pattern Formation and Solitons · Physics 2022-09-28 Igor Franović , Sebastian Eydam

We consider the dynamical effects of electromagnetic flux on the discrete Chialvo neuron. It is shown that the model can exhibit rich dynamical behaviors such as multistability, firing patterns, antimonotonicity, closed invariant curves,…

Dynamical Systems · Mathematics 2022-06-14 Sishu Shankar Muni , Hammed Olawale Fatoyinbo , Indranil Ghosh