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The Aho-Corasick algorithm is multiple patterns searching algorithm running sequentially in various applications like network intrusion detection and bioinformatics for finding several input strings within a given large input string. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-27 Vajira Thambawita , Roshan G. Ragel , Dhammike Elkaduwe

Motivation: A pan-genome graph represents a collection of genomes and encodes sequence variations between them. It is a powerful data structure for studying multiple similar genomes. Sequence-to-graph alignment is an essential step for the…

Genomics · Quantitative Biology 2022-06-29 Haowen Zhang , Shiqi Wu , Srinivas Aluru , Heng Li

Matrix multiplication is a foundational operation in scientific computing and machine learning, yet its computational complexity makes it a significant bottleneck for large-scale applications. The shift to parallel architectures, primarily…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-30 Mufakir Qamar Ansari , Mudabir Qamar Ansari

Massively parallel hardware (GPUs) and long sequence data have made parallel algorithms essential for machine learning at scale. Yet dynamical systems, like recurrent neural networks and Markov chain Monte Carlo, were thought to suffer from…

Numerical Analysis · Mathematics 2026-03-18 Xavier Gonzalez

For the problem whether Graphic Processing Unit(GPU),the stream processor with high performance of floating-point computing is applicable to neural networks, this paper proposes the parallel recognition algorithm of Convolutional Neural…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-28 Yi-bin Huang , Kang Li , Ge Wang , Min Cao , Pin Li , Yu-jia Zhang

This paper focuses on pattern matching in the DNA sequence. It was inspired by a previously reported method that proposes encoding both pattern and sequence using prime numbers. Although fast, the method is limited to rather small pattern…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Janja Paliska Soldo , Ana Sovic Krzic , and Damir Sersic

Quality-Diversity (QD) optimization algorithms are a well-known approach to generate large collections of diverse and high-quality solutions. However, derived from evolutionary computation, QD algorithms are population-based methods which…

Neural and Evolutionary Computing · Computer Science 2022-10-11 Bryan Lim , Maxime Allard , Luca Grillotti , Antoine Cully

Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

The deep neural networks (DNNs) have been enormously successful in tasks that were hitherto in the human-only realm such as image recognition, and language translation. Owing to their success the DNNs are being explored for use in ever more…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-20 Sanket Tavarageri , Srinivas Sridharan , Bharat Kaul

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

This paper presents a comprehensive comparison of three dominant parallel programming models in High Performance Computing (HPC): Message Passing Interface (MPI), Open Multi-Processing (OpenMP), and Compute Unified Device Architecture…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-19 Nizar ALHafez , Ahmad Kurdi

Pattern matching on large graphs is the foundation for a variety of application domains. Strict latency requirements and continuously increasing graph sizes demand the usage of highly parallel in-memory graph processing engines that need to…

Databases · Computer Science 2017-06-15 Alexander Krause , Annett Ungethüm , Thomas Kissinger , Dirk Habich , Wolfgang Lehner

The maximal sensitivity of the Smith-Waterman (SW) algorithm has enabled its wide use in biological sequence database search. Unfortunately, the high sensitivity comes at the expense of quadratic time complexity, which makes the algorithm…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Yongchao Liu , Bertil Schmidt

Motivation: The multiple sequence alignment (MSA) problem has been extensively studied, with numerous approaches developed over recent years. With the rapid growth of sequence data, there is an increasing need for fast and accurate MSA…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Emily G. Light , Morgan Prior , Noah M. Daniels , Najib Ishaq

Analysis of DNA samples is an important step in forensics, and the speed of analysis can impact investigations. Comparison of DNA sequences is based on the analysis of short tandem repeats (STRs), which are short DNA sequences of 2-5 base…

Performance · Computer Science 2018-03-07 Siddharth Samsi , Brian Helfer , Jeremy Kepner , Albert Reuther , Darrell O. Ricke

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Motivation: Recent advances in sequencing technologies promise ultra-long reads of $\sim$100 kilo bases (kb) in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 mega bases (Mb) in length. Existing…

Genomics · Quantitative Biology 2018-09-17 Heng Li

Mixed-precision neural network (MPNN) that utilizes just enough data width for the neural network processing is an effective approach to meet the stringent resources constraints including memory and computing of MCUs. Nevertheless, there is…

Hardware Architecture · Computer Science 2024-07-29 Junfeng Gong , Cheng Liu , Long Cheng , Huawei Li , Xiaowei Li

Sequence alignment algorithms are a basic and critical component of many bioinformatics fields. With rapid development of sequencing technology, the fast growing reference database volumes and longer length of query sequence become new…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-01-09 Bo Xu , Changlong Li , Hang Zhuang , Jiali Wang , Qingfeng Wang , Jinhong Zhou , Xuehai Zhou

Parallel computing can offer an enormous advantage regarding the performance for very large applications in almost any field: scientific computing, computer vision, databases, data mining, and economics. GPUs are high performance many-core…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-24 Bogdan Oancea , Tudorel Andrei , Raluca Mariana Dragoescu