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A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…

Optimization and Control · Mathematics 2017-03-09 Sebastian Anita , Vincenzo Capasso

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

Populations and Evolution · Quantitative Biology 2012-08-17 Joel C. Miller

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

We propose the deep demixing (DDmix) model, a graph autoencoder that can reconstruct epidemics evolving over networks from partial or aggregated temporal information. Assuming knowledge of the network topology but not of the epidemic model,…

Social and Information Networks · Computer Science 2023-06-14 Boning Li , Gojko Čutura , Ananthram Swami , Santiago Segarra

In this work we demonstrate how to automate parts of the infectious disease-control policy-making process via performing inference in existing epidemiological models. The kind of inference tasks undertaken include computing the posterior…

We investigate the use of hybrid techniques in complex processes of infectious diseases. Since predictive disease models in biomedicine require a multiscale approach for understanding the molecule-cell-tissue-organ-body interactions,…

Logic in Computer Science · Computer Science 2012-08-21 Pietro Liò , Emanuela Merelli , Nicola Paoletti

In this paper, a unified susceptible-exposed-infected-susceptible-aware (SEIS-A) framework is proposed to combine epidemic spreading with individuals' on-line self-consultation behaviors. An epidemic spreading prediction model is…

Computational Engineering, Finance, and Science · Computer Science 2019-12-02 Yun Feng , Bing-Chuan Wang

Understanding the impact of collective social phenomena in epidemic dynamics is a crucial task to effectively contain the disease spread. In this work we build a mathematical description for assessing the interplay between opinion…

Physics and Society · Physics 2023-03-10 Mattia Zanella

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Infectious disease forecasting for ongoing epidemics has been traditionally performed, communicated, and evaluated as numerical targets - 1, 2, 3, and 4 week ahead cases, deaths, and hospitalizations. While there is great value in…

Applications · Statistics 2022-11-15 Ajitesh Srivastava , Satwant Singh , Fiona Lee

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

In science, we are interested not only in forecasting but also in understanding how predictions are made, specifically what the interpretable underlying model looks like. Data-driven machine learning technology can significantly streamline…

Symbolic Computation · Computer Science 2025-05-29 Weiting Liu , Jiaxu Cui , Jiao Hu , En Wang , Bo Yang

The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Anja C. Slim , Erik M. Volz

Epidemic modeling is essential for public health planning, yet traditional approaches rely on fixed model classes that require manual redesign as pathogens, policies, and scenario assumptions evolve. We introduce EPIAGENT, an agentic…

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

Machine Learning · Computer Science 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

We propose an integral model describing an epidemic of an infectious disease. The model is behavioural in the sense that the constitutive law for the force of infection includes a distributed delay, called "information index", that…

Dynamical Systems · Mathematics 2024-05-31 Bruno Buonomo , Eleonora Messina , Claudia Panico , Antonia Vecchio

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

Applications · Statistics 2024-03-07 Giacomo Lancia , Meri Varkila , Olaf Cremer , Cristian Spitoni

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

Epidemic decision-making can effectively help the government to comprehensively consider public security and economic development to respond to public health and safety emergencies. Epidemic decision-making can effectively help the…

Machine Learning · Computer Science 2023-11-06 Yangxi Zhou , Junping Du , Zhe Xue , Zhenhui Pan , Weikang Chen

Drug resistance and strong contacts actually play crucial roles in epidemic spread in complex systems. Nevertheless, neither theoretical model or methodology is proposed to address this. We thus consider an edge-based epidemic spread model…

Physics and Society · Physics 2017-09-13 Peng-Bi Cui , Lei Gao , Wei Wang