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The traffic of molecular motors through open tube-like compartments is studied using lattice models. These models exhibit boundary-induced phase transitions related to those of the asymmetric simple exclusion process (ASEP) in one…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

We study the diffusive motion of a test particle in a two-dimensional comb structure consisting of a main backbone channel with continuously distributed side branches, in the presence of stochastic Markovian resetting to the initial…

Statistical Mechanics · Physics 2021-05-19 R. K. Singh , T. Sandev , A. Iomin , R. Metzler

Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

Biological Physics · Physics 2012-09-28 Bartosz Lisowski , Michał Żabicki

A novel mechanism for the transport of microscale particles in viscous fluids is demonstrated. The mechanism exploits the trapping of such particles by rotational streaming cells established in the vicinity of an oscillating cylinder,…

Fluid Dynamics · Physics 2016-01-13 Kwitae Chong , Scott D. Kelly , Stuart T. Smith , Jeff D. Eldredge

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

We investigate tracer transport on random discrete fracture networks that are characterized by the statistics of the fracture geometry and hydraulic conductivity. While it is well known that tracer transport through fractured media can be…

Fluid Dynamics · Physics 2017-09-13 Peter Kang , Marco Dentz , Tanguy Le Borgne , Seunghak Lee , Ruben Juanes

Fluctuations in the physical properties of biological machines are inextricably linked to their functions. Distributions of run-lengths and velocities of processive molecular motors, like kinesin-1, are accessible through single molecule…

Statistical Mechanics · Physics 2016-08-17 Huong T. Vu , Shaon Chakrabarti , Michael Hinczewski , D. Thirumalai

Analysis with the characteristic functional of stochastic motion is used for the gradient spin echo measurement of restricted motion to clarify details of the diffraction-like effect in a porous structure. It gives the diffusive diffraction…

Materials Science · Physics 2010-10-07 Janez Stepisnik

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

Soft Condensed Matter · Physics 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

Motility is an essential factor for an organism's survival and diversification. With the advent of novel single-cell technologies, analytical frameworks and theoretical methods, we can begin to probe the complex lives of microscopic motile…

Understanding the behavior of complex molecular systems is a fundamental problem in physical chemistry. To describe the long-time dynamics of such systems, which is responsible for their most informative characteristics, we can identify a…

Chemical Physics · Physics 2024-09-11 Jakub Rydzewski

Molecular Dynamics (MD) is a powerful computational microscope for probing protein functions. However, the need for fine-grained integration and the long timescales of biomolecular events make MD computationally expensive. To address this,…

Machine Learning · Computer Science 2026-03-30 Kacper Kapuśniak , Cristian Gabellini , Michael Bronstein , Prudencio Tossou , Francesco Di Giovanni

Motivated by applications in movement ecology, in this paper I propose a new class of integrated continuous-time hidden Markov models in which each observation depends on the underlying state of the process over the whole interval since the…

Methodology · Statistics 2019-10-01 Paul G Blackwell

Intracellular transport of cargoes in the cell is essential for the organization and functioning cells, especially those that are large and elongated. The cytoskeletal networks inside large cells can be highly complex, and this cytoskeletal…

Biological Physics · Physics 2023-08-04 Nimisha Krishnan , Niranjan Sarpangala , Maria Gamez , Ajay Gopinathan , Jennifer L Ross

The diffusive transport of biased Brownian particles in a two-dimensional symmetric channel is investigated numerically considering both the no-flow and the reflection boundary conditions at the channel boundaries. Here, the geometrical…

Soft Condensed Matter · Physics 2019-09-10 Narender Khatri , P. S. Burada

We present a microscopic model of a charge carrier transfer under an action of a constant electric field in a complex medium. Generalizing previous theoretical approaches, we model the dynamical environment hindering the carrier motion by…

Statistical Mechanics · Physics 2009-11-11 O. Benichou , J. Klafter , M. Moreau , G. Oshanin

The transport of bio-particles in viscous flows exhibits a rich variety of dynamical behaviour, such as morphological transitions, complex orientation dynamics or deformations. Characterising such complex behaviour under well controlled…

There is an increasing need to comprehensively characterize the kinematic performances of different Micromobility Vehicles (MMVs). This study aims to: 1) characterize the kinematic behaviors of different MMVs during emergency maneuvers; 2)…

Data Analysis, Statistics and Probability · Physics 2023-12-25 Paolo Terranova , Shu-Yuan Liu , Sparsh Jain , Johan Engstrom , Miguel Perez

Stochastic transitions between discrete microscopic states play an important role in many physical and biological systems. Often, these transitions lead to fluctuations on a macroscopic scale. A classic example from neuroscience is the…

Statistical Mechanics · Physics 2024-02-20 Lukas Ramlow , Benjamin Lindner

Intracellular transport processes driven by molecular motors can be described by stochastic lattice models of self-driven particles. Here we focus on bidirectional transport models excluding the exchange of particles on the same track. We…

Biological Physics · Physics 2015-05-27 M. Ebbinghaus , C. Appert-Rolland , L. Santen
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