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Recent advances in multimodal large language models have enabled unified processing of visual and textual inputs, offering promising applications in general-purpose medical AI. However, their ability to generalize compositionally across…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Pooja Singh , Siddhant Ujjain , Tapan Kumar Gandhi , Sandeep Kumar

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

3D medical image analysis is of great importance in disease diagnosis and treatment. Recently, multimodal large language models (MLLMs) have exhibited robust perceptual capacity, strong cross-modal alignment, and promising generalizability.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yang Yu , Dunyuan Xu , Yaoqian Li , Xiaomeng Li , Jinpeng Li , Pheng-Ann Heng

Neural networks can be powerful function approximators, which are able to model high-dimensional feature distributions from a subset of examples drawn from the target distribution. Naturally, they perform well at generalizing within the…

Machine Learning · Computer Science 2021-08-06 Aaron Eisermann , Jae Hee Lee , Cornelius Weber , Stefan Wermter

We explore Multimodal Large Language Models (MLLMs), which integrate LLMs like GPT-4 to handle multimodal data, including text, images, audio, and more. MLLMs demonstrate capabilities such as generating image captions and answering…

Computation and Language · Computer Science 2025-01-09 Shezheng Song , Xiaopeng Li , Shasha Li , Shan Zhao , Jie Yu , Jun Ma , Xiaoguang Mao , Weimin Zhang

Compositional generalization is the ability of a model to generalize to complex, previously unseen types of combinations of entities from just having seen the primitives. This type of generalization is particularly relevant to the semantic…

Computation and Language · Computer Science 2024-04-23 Amogh Mannekote

While mainstream machine learning methods are known to have limited ability to compositionally generalize, new architectures and techniques continue to be proposed to address this limitation. We investigate state-of-the-art techniques and…

Computation and Language · Computer Science 2021-09-23 Daniel Furrer , Marc van Zee , Nathan Scales , Nathanael Schärli

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

MLLMs have recently become a focal point in the field of artificial intelligence research. Building on the strong capabilities of LLMs, MLLMs are adept at addressing complex multi-modal tasks. With the release of GPT-4, MLLMs have gained…

Machine Learning · Computer Science 2025-05-01 Jiarui Ye , Hao Tang

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Multi-modal large language models (MLLMs) have shown impressive capabilities as a general-purpose interface for various visual and linguistic tasks. However, building a unified MLLM for multi-task learning in the medical field remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Xun Zhu , Ying Hu , Fanbin Mo , Miao Li , Ji Wu

While LLMs have emerged as performant architectures for reasoning tasks, their compositional generalization capabilities have been questioned. In this work, we introduce a Compositional Generalization Challenge for Graph-based Commonsense…

Computation and Language · Computer Science 2024-10-10 Xiyan Fu , Anette Frank

Medicine is inherently multimodal and multitask, with diverse data modalities spanning text, imaging. However, most models in medical field are unimodal single tasks and lack good generalizability and explainability. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Lijian Xu , Hao Sun , Ziyu Ni , Hongsheng Li , Shaoting Zhang

Systematic generalization refers to the capacity to understand and generate novel combinations from known components. Despite recent progress by large language models (LLMs) across various domains, these models often fail to extend their…

Artificial Intelligence · Computer Science 2026-02-27 Philipp Mondorf , Shijia Zhou , Monica Riedler , Barbara Plank

Skill composition is the ability to combine previously learned skills to solve new tasks. As neural networks acquire increasingly complex skills during their pretraining, it is not clear how successfully they can compose them. In this…

Computation and Language · Computer Science 2026-03-10 Paula Ontalvilla , Aitor Ormazabal , Gorka Azkune

Multimodal large language models (MLLMs) enhance the capabilities of standard large language models by integrating and processing data from multiple modalities, including text, vision, audio, video, and 3D environments. Data plays a pivotal…

Artificial Intelligence · Computer Science 2024-07-19 Tianyi Bai , Hao Liang , Binwang Wan , Yanran Xu , Xi Li , Shiyu Li , Ling Yang , Bozhou Li , Yifan Wang , Bin Cui , Ping Huang , Jiulong Shan , Conghui He , Binhang Yuan , Wentao Zhang

Multimodal large language models (MLLMs) have made impressive progress in many applications in recent years. However, chemical MLLMs that can handle cross-modal understanding and generation remain underexplored. To fill this gap, we propose…

Machine Learning · Computer Science 2025-08-05 Qian Tan , Dongzhan Zhou , Peng Xia , Wanhao Liu , Wanli Ouyang , Lei Bai , Yuqiang Li , Tianfan Fu

Generalist multimodal large language models (MLLMs) have achieved impressive performance across a wide range of vision-language tasks. However, their performance on medical tasks, particularly in zero-shot settings where generalization is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guimeng Liu , Tianze Yu , Somayeh Ebrahimkhani , Lin Zhi Zheng Shawn , Kok Pin Ng , Ngai-Man Cheung
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