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Related papers: ProtCLIP: Function-Informed Protein Multi-Modal Le…

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Despite the recent progress in incremental learning, addressing catastrophic forgetting under distributional drift is still an open and important problem. Indeed, while state-of-the-art domain incremental learning (DIL) methods perform…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Julien Nicolas , Florent Chiaroni , Imtiaz Ziko , Ola Ahmad , Christian Desrosiers , Jose Dolz

Multimodal fake news detection has attracted many research interests in social forensics. Many existing approaches introduce tailored attention mechanisms to guide the fusion of unimodal features. However, how the similarity of these…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Yangming Zhou , Qichao Ying , Zhenxing Qian , Sheng Li , Xinpeng Zhang

A large number of protein sequences are becoming available through the application of novel high-throughput sequencing technologies. Experimental functional characterization of these proteins is time-consuming and expensive, and is often…

Genomics · Quantitative Biology 2017-09-28 Maxat Kulmanov , Mohammed Asif Khan , Robert Hoehndorf

Contrastive Language-Image Pretraining (CLIP) has achieved remarkable success, leading to rapid advancements in multimodal studies. However, CLIP faces a notable challenge in terms of inefficient data utilization. It relies on a single…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Yu Zhang , Qi Zhang , Zixuan Gong , Yiwei Shi , Yepeng Liu , Duoqian Miao , Yang Liu , Ke Liu , Kun Yi , Wei Fan , Liang Hu , Changwei Wang

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Protein language models are a powerful tool for learning protein representations through pre-training on vast protein sequence datasets. However, traditional protein language models lack explicit structural supervision, despite its…

Biomolecules · Quantitative Biology 2024-02-09 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Integrating pretrained vision-language foundation models like CLIP into federated learning has attracted significant attention for enhancing generalization across diverse tasks. Typically, federated learning of vision-language models…

Machine Learning · Computer Science 2024-10-01 Bikang Pan , Wei Huang , Ye Shi

Predicting protein properties, functions and localizations are important tasks in bioinformatics. Recent progress in machine learning offers an opportunities for improving existing methods. We developed a new approach called ProtBoost,…

Quantitative Methods · Quantitative Biology 2024-12-09 Alexander Chervov , Anton Vakhrushev , Sergei Fironov , Loredana Martignetti

Human motion generation is essential for fields such as animation, robotics, and virtual reality, requiring models that effectively capture motion dynamics from text descriptions. Existing approaches often rely on Contrastive Language-Image…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Gabriel Maldonado , Armin Danesh Pazho , Ghazal Alinezhad Noghre , Vinit Katariya , Hamed Tabkhi

Protein language models often take into consideration the alignment between a protein sequence and its textual description. However, they do not take structural information into consideration. Traditional methods treat sequence and…

Machine Learning · Computer Science 2026-03-10 Aditya Ranganath , Hasin Us Sami , Kowshik Thopalli , Bhavya Kailkhura , Wesam Sakla

The diverse nature of protein prediction tasks has traditionally necessitated specialized models, hindering the development of broadly applicable and computationally efficient Protein Language Models (PLMs). In this work, we introduce…

Contrastive Language-Image Pre-training (CLIP) represents the latest incarnation of pre-trained vision-language models. Although CLIP has recently shown its superior power on a wide range of downstream vision-language tasks like Visual…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Sinuo Deng , Lifang Wu , Ge Shi , Lehao Xing , Meng Jian , Ye Xiang

Protein-protein interactions (PPIs) are essentials for many biological processes where two or more proteins physically bind together to achieve their functions. Modeling PPIs is useful for many biomedical applications, such as vaccine…

Biomolecules · Quantitative Biology 2021-12-10 Yang Xue , Zijing Liu , Xiaomin Fang , Fan Wang

Fashion vision-language pre-training models have shown efficacy for a wide range of downstream tasks. However, general vision-language pre-training models pay less attention to fine-grained domain features, while these features are…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Yunpeng Han , Lisai Zhang , Qingcai Chen , Zhijian Chen , Zhonghua Li , Jianxin Yang , Zhao Cao

Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

Cross-modal pre-training has shown impressive performance on a wide range of downstream tasks, benefiting from massive image-text pairs collected from the Internet. In practice, online data are growing constantly, highlighting the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Xinchi Deng , Han Shi , Runhui Huang , Changlin Li , Hang Xu , Jianhua Han , James Kwok , Shen Zhao , Wei Zhang , Xiaodan Liang

Contrastive Language-Image Pre-training (CLIP)~\citep{radford2021learning} has emerged as a pivotal model in computer vision and multimodal learning, achieving state-of-the-art performance at aligning visual and textual representations…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shaoan Xie , Lingjing Kong , Yujia Zheng , Yu Yao , Zeyu Tang , Eric P. Xing , Guangyi Chen , Kun Zhang

Effective protein representation learning is crucial for predicting protein functions. Traditional methods often pretrain protein language models on large, unlabeled amino acid sequences, followed by finetuning on labeled data. While…

Biomolecules · Quantitative Biology 2024-09-05 Jiangbin Zheng , Stan Z. Li

Protein language models have shown remarkable success in learning biological information from protein sequences. However, most existing models are limited by either autoencoding or autoregressive pre-training objectives, which makes them…

Quantitative Methods · Quantitative Biology 2024-12-10 Bo Chen , Xingyi Cheng , Pan Li , Yangli-ao Geng , Jing Gong , Shen Li , Zhilei Bei , Xu Tan , Boyan Wang , Xin Zeng , Chiming Liu , Aohan Zeng , Yuxiao Dong , Jie Tang , Le Song

While multi-modal Visual Language Models (VLMs) have demonstrated significant success across various domains, the integration of VLMs into recommendation and retrieval systems remains a challenge, due to issues like training objective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Josh Beal , Eric Kim , Jinfeng Rao , Rex Wu , Dmitry Kislyuk , Charles Rosenberg