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Motivation: Automatic Anatomical Therapeutic Chemical (ATC) classification is a critical and highly competitive area of research in bioinformatics because of its potential for expediting drug develop-ment and research. Predicting an unknown…

Quantitative Methods · Quantitative Biology 2021-08-09 Loris Nanni , Alessandra Lumini , Sheryl Brahnam

The versatility of multimodal deep learning holds tremendous promise for advancing scientific research and practical applications. As this field continues to evolve, the collective power of cross-modal analysis promises to drive…

Machine Learning · Computer Science 2025-05-15 Yifei Wang , Yunrui Li , Lin Liu , Pengyu Hong , Hao Xu

Accurate and efficient network traffic classification is important for many network management tasks, from traffic prioritization to anomaly detection. Although classifiers using pre-computed flow statistics (e.g., packet sizes,…

Networking and Internet Architecture · Computer Science 2023-02-24 Xi Jiang , Shinan Liu , Saloua Naama , Francesco Bronzino , Paul Schmitt , Nick Feamster

Prediction of new drug-target interactions is extremely important as it can lead the researchers to find new uses for old drugs and to realize the therapeutic profiles or side effects thereof. However, experimental prediction of drug-target…

Computational Engineering, Finance, and Science · Computer Science 2017-07-05 Farshid Rayhan , Sajid Ahmed , Swakkhar Shatabda , Dewan Md Farid , Zaynab Mousavian , Abdollah Dehzangi , M Sohel Rahman

Machine learning and deep learning advancements have boosted Brain-Computer Interface (BCI) performance, but their wide-scale applicability is limited due to factors like individual health, hardware variations, and cultural differences…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Christian Flores , Marcelo Contreras , Ichiro Macedo , Javier Andreu-Perez

Neuro-developmental disorders are manifested as dysfunctions in cognition, communication, behaviour and adaptability, and deep learning-based computer-aided diagnosis (CAD) can alleviate the increasingly strained healthcare resources on…

Machine Learning · Computer Science 2026-04-17 Xin Wen , Shijie Guo , Wenbo Ning , Rui Cao , Jie Xiang , Xiaobo Liu , Jintai Chen

Transfer learning represents a recent paradigm shift in the way we build artificial intelligence (AI) systems. In contrast to training task-specific models, transfer learning involves pre-training deep learning models on a large corpus of…

The 3D point cloud (3DPC) has significantly evolved and benefited from the advance of deep learning (DL). However, the latter faces various issues, including the lack of data or annotated data, the existence of a significant gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Shahab Saquib Sohail , Yassine Himeur , Hamza Kheddar , Abbes Amira , Fodil Fadli , Shadi Atalla , Abigail Copiaco , Wathiq Mansoor

Accurate prediction of molecular properties underpins drug discovery and material design, yet even state-of-the-art models remain vulnerable to localized failure modes that aggregate metrics cannot detect. The places where molecular…

Machine Learning · Computer Science 2026-05-19 Di Hu , Kun Li , Haojie Rao , Longtao Hu , Jiameng Chen , Wenbin Hu , Yizhen Zheng , Jiajun Yu , Duanhua Cao

Drug-target interaction prediction (DTI) is essential in various applications including drug discovery and clinical application. There are two perspectives of input data widely used in DTI prediction: Intrinsic data represents how drugs or…

Machine Learning · Computer Science 2025-03-21 Xinlong Zhai , Chunchen Wang , Ruijia Wang , Jiazheng Kang , Shujie Li , Boyu Chen , Tengfei Ma , Zikai Zhou , Cheng Yang , Chuan Shi

Exploring methods and techniques of machine learning (ML) to address specific challenges in various fields is essential. In this work, we tackle a problem in the domain of Cheminformatics; that is, providing a suitable solution to aid in…

Biomolecules · Quantitative Biology 2024-01-03 Do Hoang Tu , Tran Van Lang , Pham Cong Xuyen , Le Mau Long

In the domain of causal inference research, the prevalent potential outcomes framework, notably the Rubin Causal Model (RCM), often overlooks individual interference and assumes independent treatment effects. This assumption, however, is…

Methodology · Statistics 2024-02-21 Hongtao Zhu , Sizhe Zhang , Yang Su , Zhenyu Zhao , Nan Chen

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning has been a subject of intense research in recent years. Recent success of deep learning in computer vision has progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Naimul Mefraz Khan , Marcia Hon , Nabila Abraham

One important desideratum of lifelong learning aims to discover novel classes from unlabelled data in a continuous manner. The central challenge is twofold: discovering and learning novel classes while mitigating the issue of catastrophic…

Artificial Intelligence · Computer Science 2024-03-07 Guangyao Chen , Peixi Peng , Yangru Huang , Mengyue Geng , Yonghong Tian

Alzheimer's disease (AD) is a common neurodegenerative disease among the elderly. Early prediction and timely intervention of its prodromal stage, mild cognitive impairment (MCI), can decrease the risk of advancing to AD. Combining…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Xiangyang Hu , Xiangyu Shen , Yifei Sun , Xuhao Shan , Wenwen Min , Liyilei Su , Xiaomao Fan , Ahmed Elazab , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan

The needs for precisely estimating a student's academic performance have been emphasized with an increasing amount of attention paid to Intelligent Tutoring System (ITS). However, since labels for academic performance, such as test scores,…

Computers and Society · Computer Science 2021-07-13 Byungsoo Kim , Hangyeol Yu , Dongmin Shin , Youngduck Choi

To enable personalized cancer treatment, machine learning models have been developed to predict drug response as a function of tumor and drug features. However, most algorithm development efforts have relied on cross validation within a…

Drug combinations can cause adverse drug-drug interactions(DDIs). Identifying specific effects is crucial for developing safer therapies. Previous works on DDI event prediction have typically been limited to using labels of specific events…

Biomolecules · Quantitative Biology 2024-11-05 Yingying Wang , Yun Xiong , Xixi Wu , Xiangguo Sun , Jiawei Zhang

Team adaptation to new cooperative tasks is a hallmark of human intelligence, which has yet to be fully realized in learning agents. Previous work on multi-agent transfer learning accommodate teams of different sizes, heavily relying on the…

Artificial Intelligence · Computer Science 2022-03-10 Rongjun Qin , Feng Chen , Tonghan Wang , Lei Yuan , Xiaoran Wu , Zongzhang Zhang , Chongjie Zhang , Yang Yu

Click-through rate (CTR) prediction is a critical task in online advertising and recommender systems, relying on effective modeling of feature interactions. Explicit interactions capture predefined relationships, such as inner products, but…

Information Retrieval · Computer Science 2025-05-27 Kefan Wang , Hao Wang , Wei Guo , Yong Liu , Jianghao Lin , Defu Lian , Enhong Chen