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Decoding visual-semantic information from brain signals, such as functional MRI (fMRI), across different subjects poses significant challenges, including low signal-to-noise ratio, limited data availability, and cross-subject variability.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Ruizhe Zheng , Lichao Sun

Decoding functional magnetic resonance imaging (fMRI) signals into text has been a key challenge in the neuroscience community, with the potential to advance brain-computer interfaces and uncover deeper insights into brain mechanisms.…

Neurons and Cognition · Quantitative Biology 2025-06-10 Weikang Qiu , Zheng Huang , Haoyu Hu , Aosong Feng , Yujun Yan , Rex Ying

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Cross-subject generalization in biomedical time-series refers to training on data from some subjects and testing on unseen subjects.The key challenge is to suppress subject specific variability in BTS representations.Most existing methods…

Machine Learning · Computer Science 2026-05-27 Guikang Du , Haoran Li , Xinyu Liu , Zhibo Zhang , Xiaoli Gong , Jin Zhang

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Decoding brain states from functional magnetic resonance imaging (fMRI) data is vital for advancing neuroscience and clinical applications. While traditional machine learning and deep learning approaches have made strides in leveraging the…

Machine Learning · Computer Science 2025-12-10 Danial Jafarzadeh Jazi , Maryam Hajiesmaeili

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

Neurons and Cognition · Quantitative Biology 2025-10-17 Roy Urbach , Elad Schneidman

Reconstructing the viewed images from human brain activity bridges human and computer vision through the Brain-Computer Interface. The inherent variability in brain function between individuals leads existing literature to focus on…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Ruijie Quan , Wenguan Wang , Zhibo Tian , Fan Ma , Yi Yang

Recent advances in MRI have led to the creation of large datasets. With the increase in data volume, it has become difficult to locate previous scans of the same patient within these datasets (a process known as re-identification). To…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Lemuel Puglisi , Frederik Barkhof , Daniel C. Alexander , Geoffrey JM Parker , Arman Eshaghi , Daniele Ravì

Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Contemporary computational neuroscience features two prominent modeling traditions. Bottom-up whole-brain modeling (WBM) builds biophysically detailed simulations of brain structure and dynamics, whereas top-down neuroconnectionism…

Neurons and Cognition · Quantitative Biology 2026-05-19 Mario Senden , Leonardo Dalla Porta , Jan Fousek , Jorge F. Mejias , Gorka Zamora-López

Current large speech language models are mainly based on semantic tokens from discretization of self-supervised learned representations and acoustic tokens from a neural codec, following a semantic-modeling and acoustic-synthesis paradigm.…

Sound · Computer Science 2025-10-16 Xue Jiang , Xiulian Peng , Yuan Zhang , Yan Lu

Reconstructing visual stimuli from human brain activity (e.g., fMRI) bridges neuroscience and computer vision by decoding neural representations. However, existing methods often overlook critical brain structure-function relationships,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Sijin Yu , Zijiao Chen , Wenxuan Wu , Shengxian Chen , Zhongliang Liu , Jingxin Nie , Xiaofen Xing , Xiangmin Xu , Xin Zhang

Decoding visual experiences from fMRI offers a powerful avenue to understand human perception and develop advanced brain-computer interfaces. However, current progress often prioritizes maximizing reconstruction fidelity while overlooking…

Machine Learning · Computer Science 2025-10-09 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

Decoding inner speech from the brain signal via hybridisation of fMRI and EEG data is explored to investigate the performance benefits over unimodal models. Two different bimodal fusion approaches are examined: concatenation of probability…

The past few years have seen remarkable progress in the decoding of speech from brain activity, primarily driven by large single-subject datasets. However, due to individual variation, such as anatomy, and differences in task design and…

Machine Learning · Computer Science 2025-06-03 Dulhan Jayalath , Gilad Landau , Brendan Shillingford , Mark Woolrich , Oiwi Parker Jones

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

We investigate optimal strategies for decoding perceived natural speech from fMRI data acquired from a limited number of participants. Leveraging Lebel et al. (2023)'s dataset of 8 participants, we first demonstrate the effectiveness of…

Neurons and Cognition · Quantitative Biology 2025-05-28 Louis Jalouzot , Alexis Thual , Yair Lakretz , Christophe Pallier , Bertrand Thirion

Recent work has demonstrated that complex visual stimuli can be decoded from human brain activity using deep generative models, offering new ways to probe how the brain represents real-world scenes. However, many existing approaches first…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Pinyuan Feng , Hossein Adeli , Wenxuan Guo , Fan Cheng , Ethan Hwang , Nikolaus Kriegeskorte
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