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Spatially resolved transcriptomics (ST) measures gene expression along with the spatial coordinates of the measurements. The analysis of ST data involves significant computation complexity. In this work, we propose gene expression…

Genomics · Quantitative Biology 2022-05-24 Zhuoyan Xu , Kris Sankaran

Metasurfaces have been proposed as a new paradigm to manipulate light and improve light-matter interactions. Conventional metasurfaces are restricted to the loss of materials, limiting their performance ceiling. Here, the loss of metallic…

Optics · Physics 2023-11-02 Yisheng Gao

In wavelet shrinkage and thresholding, most of the standard techniques do not consider information that wavelet coefficients might be bounded, although information about bounded energy in signals can be readily available. To address this,…

Methodology · Statistics 2020-11-12 Alex Rodrigo dos Santos Sousa , Nancy Lopes Garcia , Branislav Vidakovic

Sparse Autoencoders (SAEs) have emerged as a predominant tool in mechanistic interpretability, aiming to identify interpretable monosemantic features. However, how does sparse encoding organize the representations of activation vector from…

Machine Learning · Computer Science 2025-05-29 Wenjie Sun , Bingzhe Wu , Zhile Yang , Chengke Wu

A new approach to the solution of boundary value problems within the so-called fictitious domain methods philosophy is proposed which avoids well known shortcomings of other fictitious domain methods, including the need to generate…

Numerical Analysis · Mathematics 2019-01-17 Daniel Agress , Patrick Guidotti

The standard theory of stochastic approximation (SA) is extended to the case when the constraint set is a Riemannian manifold. Specifically, the standard ODE method for analyzing SA schemes is extended to iterations constrained to stay on a…

Optimization and Control · Mathematics 2017-11-30 Suhail M. Shah

Parameter prediction is essential for many applications, facilitating insightful interpretation and decision-making. However, in many real life domains, such as power systems, medicine, and engineering, it can be very expensive to acquire…

Machine Learning · Computer Science 2024-02-16 Zimeng Lyu , Alexander Ororbia , Rui Li , Travis Desell

We study the estimation of quadratic Sobolev-type integral functionals of an unknown density on the unit sphere. The functional is defined through fractional powers of the Laplace--Beltrami operator and provides a global measure of…

Statistics Theory · Mathematics 2026-02-05 Claudio Durastanti

We implement a shape optimization algorithm for body-assisted light-matter interactions described by the formalism of macroscopic quantum electrodynamics. The approach uses the level-set method to represent and incrementally evolve…

Quantum Physics · Physics 2022-09-09 Jonas Matuszak , Stefan Yoshi Buhmann , Robert Bennett

Three different methods to quantize the spherically symmetric sector of electromagnetism are presented: First, it is shown that this sector is equivalent to Abelian BF-theory in four spacetime dimensions with suitable boundary conditions.…

High Energy Physics - Theory · Physics 2010-11-19 Martin Bojowald

Methodologies for reducing the design-space dimensionality in shape optimization have been recently developed based on unsupervised machine learning methods. These methods provide reduced dimensionality representations of the design space,…

Optimization and Control · Mathematics 2022-12-21 Andrea Serani , Matteo Diez

In this paper, we propose a unified energy minimization model for the segmentation of non-smooth image structures. The energy of piecewise linear patch reconstruction is considered as an objective measure of the quality of the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2014-04-08 Junyan Wang , Kap Luk Chan

The area renormalization procedure gives an invariant of even-dimensional closed submanifolds in a conformal manifold, which we call the Graham-Witten energy, and it is a generalization of the classical Willmore energy. In this paper, we…

Differential Geometry · Mathematics 2020-01-22 Yuya Takeuchi

In this work, we investigate a skew-symmetric parameterization for energy-preserving quadratic operators. Earlier, [Goyal et al., 2023] proposed this parameterization to enforce energy-preservation for quadratic terms in the context of…

Numerical Analysis · Mathematics 2025-03-17 Leonidas Gkimisis , Igor Pontes Duff , Pawan Goyal , Peter Benner

In this paper, we introduce Segmentation-Driven Deformation Multi-View Stereo (SD-MVS), a method that can effectively tackle challenges in 3D reconstruction of textureless areas. We are the first to adopt the Segment Anything Model (SAM) to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Zhenlong Yuan , Jiakai Cao , Zhaoxin Li , Hao Jiang , Zhaoqi Wang

We consider a two-dimensional sharp-interface model for solid-state dewetting of thin films with anisotropic surface energies on curved substrates, where the film/vapor interface and substrate surface are represented by an evolving and a…

Numerical Analysis · Mathematics 2024-10-02 Weizhu Bao , Yifei Li , Quan Zhao

In this paper, we propose a new approach -- the Tempered Finite Element Method (TFEM) -- that extends the Finite Element Method (FEM) to classes of meshes that include zero-measure or nearly degenerate elements for which standard FEM…

Numerical Analysis · Mathematics 2024-11-27 Antoine Quiriny , Václav Kučera , Jonathan Lambrechts , Nicolas Moës , Jean-François Remacle

Beampattern synthesis seeks to optimize array weights to shape radiation patterns, playing a critical role in various wireless applications. In addition to theoretical advancements, recent hardware innovations have facilitated new avenues…

Signal Processing · Electrical Eng. & Systems 2025-03-07 Pinjun Zheng , Md. Jahangir Hossain , Anas Chaaban

We use the general framework of summation-by-parts operators to construct conservative, energy-stable, and well-balanced semidiscretizations of two different nonlinear systems of dispersive shallow water equations with varying bathymetry:…

Numerical Analysis · Mathematics 2025-11-12 Joshua Lampert , Hendrik Ranocha

A widely used strategy to reduce the computational cost in quantum-chemical calculations is to partition the system into an active subsystem, which is the focus of the computational efforts and an environment that is treated at a lower…

Chemical Physics · Physics 2023-06-19 Elena Kolodzeiski , Christopher J. Stein
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