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Due to the scarcity of quantitative details about biological phenomena, quantitative modeling in systems biology can be compromised, especially at the subcellular scale. One way to get around this is qualitative modeling because it requires…

Molecular Networks · Quantitative Biology 2019-03-22 Arnaud Poret , Claudio Monteiro Sousa , Jean-Pierre Boissel

Chaos control in Random Boolean networks is implemented by freezing part of the network to drive it from chaotic to ordered phase. However, controlled nodes are only viewed as passive blocks to prevent perturbation spread. This paper…

Cellular Automata and Lattice Gases · Physics 2015-05-20 Nan Jiang , Shijian Chen

This paper explores methods for verifying the properties of Binary Neural Networks (BNNs), focusing on robustness against adversarial attacks. Despite their lower computational and memory needs, BNNs, like their full-precision counterparts,…

Machine Learning · Computer Science 2025-04-16 Jianting Yang , Srećko Ðurašinović , Jean-Bernard Lasserre , Victor Magron , Jun Zhao

Linear dynamical systems are canonical models for learning-based control of plants with uncertain dynamics. The setting consists of a stochastic differential equation that captures the state evolution of the plant understudy, while the true…

Systems and Control · Electrical Eng. & Systems 2022-01-03 Mohamad Kazem Shirani Faradonbeh , Mohamad Sadegh Shirani Faradonbeh

The control of biological systems presents interesting applications such as cell reprogramming or drug target identification. A common type of control strategy consists in a set of interventions that, by fixing the values of some variables,…

Molecular Networks · Quantitative Biology 2021-12-21 Laura Cifuentes Fontanals , Elisa Tonello , Heike Siebert

We consider the set of bimodal linear systems consisting of two linear dynamics acting on each side of a given hyperplane, assuming continuity along the separating hyperplane. Focusing on the unobservable planar ones, we obtain a simple…

Dynamical Systems · Mathematics 2012-01-04 Josep Ferrer , M. Dolors Magret , Juan R. Pacha , Marta Peña

Learning Bayesian networks from raw data can help provide insights into the relationships between variables. While real data often contains a mixture of discrete and continuous-valued variables, many Bayesian network structure learning…

Artificial Intelligence · Computer Science 2018-09-19 Yi-Chun Chen , Tim Allan Wheeler , Mykel John Kochenderfer

Intensive research has been conducted on the verification and validation of deep neural networks (DNNs), aiming to understand if, and how, DNNs can be applied to safety critical applications. However, existing verification and validation…

Machine Learning · Computer Science 2021-03-08 Nicolas Berthier , Amany Alshareef , James Sharp , Sven Schewe , Xiaowei Huang

An approach to stabilization of control systems with ultimately wide ranges of uncertainly disturbed parameters is offered. The method relies on using of nonlinear structurally stable functions from catastrophe theory as controllers.…

Optimization and Control · Mathematics 2009-01-20 Viktor Ten

Symbolic models are abstract descriptions of continuous systems in which symbols represent aggregates of continuous states. In the last few years there has been a growing interest in the use of symbolic models as a tool for mitigating…

Optimization and Control · Mathematics 2007-07-31 Giordano Pola , Paulo Tabuada

We use the implicitization procedure to generate polynomial equality constraints on the set of distributions induced by local interventions on variables governed by a causal Bayesian network with hidden variables. We show how we may reduce…

Artificial Intelligence · Computer Science 2012-06-26 Changsung Kang , Jin Tian

Signed networks have been a topic of recent interest in the network control community as they allow studying antagonistic interactions in multi-agent systems. Although dynamical characteristics of signed networks have been well-studied,…

Optimization and Control · Mathematics 2017-07-13 Siavash Alemzadeh , Mathias Hudoba de Badyn , Mehran Mesbahi

We design observer-based controllers to stabilise abstract linear boundary control systems on Hilbert spaces. Our main results introduce conditions for exponential, strong, and polynomial stability, and establish external well-posedness of…

Optimization and Control · Mathematics 2026-05-28 Mohamed Fkirine , Lassi Paunonen

Both bilevel and robust optimization are established fields of mathematical optimization and operations research. However, only until recently, the similarities in their mathematical structure has neither been studied theoretically nor…

Optimization and Control · Mathematics 2026-02-20 Henri Lefebvre , Martin Schmidt , Simon Stevens , Johannes Thürauf

Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized…

Molecular Networks · Quantitative Biology 2016-09-07 Mohammad Moradi , Sama Goliaei

The study of network structure has uncovered signatures of the organization of complex systems. However, there is also a need to understand how to control them; for example, identifying strategies to revert a diseased cell to a healthy…

Molecular Networks · Quantitative Biology 2016-04-19 Alexander J. Gates , Luis M. Rocha

This paper studies the construction of dynamic symbolic abstractions for nonlinear control systems via dynamic quantization. Since computational complexity is a fundamental problem in the use of discrete abstractions, a dynamic quantizer…

Systems and Control · Electrical Eng. & Systems 2020-11-26 Wei Ren , Dimos V. Dimarogonas

This paper explores Bayesian estimation for categorical data, focusing on simple yet effective models that provide a foundation for applying more advanced methods accurately and reliably in real-world applications. We begin by revisiting…

Methodology · Statistics 2025-09-03 Jan Kalina

Boolean Networks (BNs) are established models to qualitatively describe biological systems. The analysis of BNs might be infeasible for medium to large BNs due to the state-space explosion problem. We propose a novel reduction technique…

Computational Engineering, Finance, and Science · Computer Science 2021-07-01 Georgios Argyris , Alberto Lluch Lafuente , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

This paper studies the problem of selecting a minimum-size set of input nodes to guarantee stability of a networked system in the presence of uncertainties and time delays. Current approaches to input selection in networked dynamical…

Optimization and Control · Mathematics 2017-12-13 Zhipeng Liu , Yao Long , Andrew Clark , Phillip Lee , Linda Bushnell , Daniel Kirschen , Radha Poovendran
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