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In this work we address the task of semantic image segmentation with Deep Learning and make three main contributions that are experimentally shown to have substantial practical merit. First, we highlight convolution with upsampled filters,…

Computer Vision and Pattern Recognition · Computer Science 2017-05-15 Liang-Chieh Chen , George Papandreou , Iasonas Kokkinos , Kevin Murphy , Alan L. Yuille

Accurate segmentation of retinal vessels is crucial for the clinical diagnosis of numerous ophthalmic and systemic diseases. However, traditional Convolutional Neural Network (CNN) methods exhibit inherent limitations, struggling to capture…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Hongyu Xu , Panpan Meng , Meng Wang , Dayu Hu , Liming Liang , Xiaoqi Sheng

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Tariq M Khan , Shahzaib Iqbal , Syed S. Naqvi , Imran Razzak , Erik Meijering

Automated segmentation of the optic cup and disk on retinal fundus images is fundamental for the automated detection / analysis of glaucoma. Traditional segmentation approaches depend heavily upon hand-crafted features and a priori…

Computer Vision and Pattern Recognition · Computer Science 2019-02-14 Lei Bi , Yuyu Guo , Qian Wang , Dagan Feng , Michael Fulham , Jinman Kim

Retinal fundus images provide valuable insights into the human eye's interior structure and crucial features, such as blood vessels, optic disk, macula, and fovea. However, accurate segmentation of retinal blood vessels can be challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Atifa Kalsoom , M. A. Iftikhar , Amjad Ali , Zubair Shah , Shidin Balakrishnan , Hazrat Ali

Accurate vessel segmentation is critical for clinical applications such as disease diagnosis and surgical planning, yet remains challenging due to thin, branching structures and low texture contrast. While foundation models like the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Suzhong Fu , Rui Sun , Xuan Ding , Jingqi Dong , Yiming Yang , Yao Zhu , Min Chang Jordan Ren , Delin Deng , Angelica Aviles-Rivero , Shuguang Cui , Zhen Li

Over recent years, increasingly complex approaches based on sophisticated convolutional neural network architectures have been slowly pushing performance on well-established benchmark datasets. In this paper, we take a step back to examine…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Tariq M Khan , Antonio Robles-Kelly , Syed S. Naqvi

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

We propose a novel deep-learning-based system for vessel segmentation. Existing methods using CNNs have mostly relied on local appearances learned on the regular image grid, without considering the graphical structure of vessel shape. To…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Seung Yeon Shin , Soochahn Lee , Il Dong Yun , Kyoung Mu Lee

Segmenting specific targets or biomarkers is necessary to analyze optical coherence tomography angiography (OCTA) images. Previous methods typically segment all the targets in an OCTA sample, such as retinal vessels (RVs). Although these…

Machine Learning · Computer Science 2024-03-21 Xinrun Chen , Chengliang Wang , Haojian Ning , Shiying Li , Mei Shen

The change of retinal vasculature is an early sign of many vascular and systematic diseases, such as diabetes and hypertension. Different behaviors of retinal arterioles and venules form an important metric to measure the disease severity.…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Meng Li , Yan Zhang , Haicheng She , Jinqiong Zhou , Jia Jia , Danmei He , Li Zhang

Domain-generalized retinal vessel segmentation is critical for automated ophthalmic diagnosis, yet faces significant challenges from domain shift induced by non-uniform illumination and varying contrast, compounded by the difficulty of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Chanchan Wang , Yuanfang Wang , Qing Xu , Guanxin Chen

Deep learning has been shown to produce state of the art results in many tasks in biomedical imaging, especially in segmentation. Moreover, segmentation of the cerebrovascular structure from magnetic resonance angiography is a challenging…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Pedro Sanches , Cyril Meyer , Vincent Vigon , Benoît Naegel

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have significantly impacted medical image segmentation, especially in retinal imaging, where precise segmentation is vital for diagnosis. Despite this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Shahrooz Faghihroohi , Kai Huang , Nassir Navab , M. Ali Nasseri

Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Julian Lo , Morgan Heisler , Vinicius Vanzan , Sonja Karst , Ivana Zadro Matovinovic , Sven Loncaric , Eduardo V. Navajas , Mirza Faisal Beg , Marinko V. Sarunic

Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Tariq M. Khan , Syed S. Naqvi , Antonio Robles-Kelly , Imran Razzak

Accurate cerebrovascular segmentation from Magnetic Resonance Angiography (MRA) and Computed Tomography Angiography (CTA) is of great significance in diagnosis and treatment of cerebrovascular pathology. Due to the complexity and topology…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Zhanqiang Guo , Yao Luan , Jianjiang Feng , Wangsheng Lu , Yin Yin , Guangming Yang , Jie Zhou

Vision impairment due to pathological damage of the retina can largely be prevented through periodic screening using fundus color imaging. However the challenge with large scale screening is the inability to exhaustively detect fine blood…

Machine Learning · Computer Science 2016-03-16 Debapriya Maji , Anirban Santara , Pabitra Mitra , Debdoot Sheet

Accurate segmentation of lesion regions is crucial for clinical diagnosis and treatment across various diseases. While deep convolutional networks have achieved satisfactory results in medical image segmentation, they face challenges such…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yulin Chen , Guoheng Huang , Kai Huang , Zijin Lin , Guo Zhong , Shenghong Luo , Jie Deng , Jian Zhou

Open-vocabulary semantic segmentation aims to segment images into distinct semantic regions for both seen and unseen categories at the pixel level. Current methods utilize text embeddings from pre-trained vision-language models like CLIP…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Ziyu Zhao , Xiaoguang Li , Linjia Shi , Nasrin Imanpour , Song Wang