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Related papers: A Fluid-Structure Interaction Model of the Zebrafi…

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Fluid-structure interaction (FSI) modeling, a technique widely used to enhance imaging modalities for adult and pediatric heart diseases, has been underutilized in the context of fetal circulation because of limited data on flow conditions…

Medical Physics · Physics 2024-10-29 Zhenglun Alan Wei , Guihong Chen , Biao Si , Liqun Sun , Mike Seed , Shuping Ge

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Zebrafish is a powerful and widely-used model system for a host of biological investigations including cardiovascular studies and genetic screening. Zebrafish are readily assessable during developmental stages; however, the current methods…

In this work, we present a computational fluid-structure interaction (FSI) study for a healthy patient-specific pulmonary arterial tree using the unified continuum and variational multiscale (VMS) formulation we previously developed. The…

Computational Physics · Physics 2020-08-19 Ju Liu , Weiguang Yang , Ingrid S. Lan , Alison L. Marsden

Quantifying cardiovascular parameters like ejection fraction in zebrafish as a host of biological investigations has been extensively studied. Since current manual monitoring techniques are time-consuming and fallible, several image…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Amir Mohammad Naderi , Jennifer G. Casey , Mao-Hsiang Huang , Rachelle Victorio , David Y. Chiang , Calum MacRae , Hung Cao , Vandana A. Gupta

The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves…

This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with…

Tissues and Organs · Quantitative Biology 2021-10-15 Alexander D. Kaiser , Rohan Shad , William Hiesinger , Alison L. Marsden

Fluid-structure interaction in the developing heart is an active area of research in developmental biology. However, investigation of heart dynamics is mostly limited to computational fluid dynamics simulations using heart wall structure…

Quantitative Methods · Quantitative Biology 2018-03-01 Vytautas Zickus , Jonathan M. Taylor

The present paper is concerned with numerical investigation of the performance of a pilot-operated control valve based on shape memory alloy actuation control. The valve under investigation can be integrated into miniaturized hydraulic…

Fluid Dynamics · Physics 2024-04-30 Ahmed Aissa Berraies , E. Harald van Brummelen , Ferdinando Auricchio

To accurately simulate all phases of the cardiac cycle, computational models of hemodynamics in heart chambers need to include a sufficiently faithful model of cardiac valves. This can be achieved efficiently through resistive methods, and…

Numerical Analysis · Mathematics 2025-06-05 Michele Bucelli , Luca Dede'

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

Computational Physics · Physics 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

A fluid-structure-interaction (FSI) experiment was designed and executed with a focus on producing low-frequency (~10 Hz), high-amplitude ($\pm$3.5% of the span) fin motion. This was achieved by placing a backward facing swept fin at…

Fluid-structure interaction (FSI) simulation of biological systems presents significant computational challenges, particularly for applications involving large structural deformations and contact mechanics, such as heart valve dynamics.…

Quantitative Methods · Quantitative Biology 2026-02-13 Ryan T. Black , Steve A. Maas , Wensi Wu , Jalaj Maheshwari , Tzanio Kolev , Jeffrey A. Weiss , Matthew A. Jolley

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

Medical Physics · Physics 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

We report a novel physics-informed neural framework for reconstructing unsteady fluid-structure interactions (FSI) from sparse, single-phase observations of the flow. Our approach combines a modal surface model with coordinate neural…

Fluid Dynamics · Physics 2026-04-07 Rui Tang , Ke Zhou , Jifu Tan , Samuel J. Grauer

Prosthetic heart valve interventions such as TAVR have surged over the past decade, but the associated complication of long-term, life-threatening thrombotic events continues to undermine patient outcomes. Thus, improving thrombogenic risk…

Computational Engineering, Finance, and Science · Computer Science 2024-06-19 Kyle Baylous , Brandon Kovarovic , Salwa Anam , Ryan Helbock , Marvin Slepian , Danny Bluestein

Passive flow control via fluid-structure interaction (FSI) is a promising paradigm for unmanned aerial vehicles operating in vortex-dominated low Reynolds number regimes. A flexible structure has the potential to passively alter key…

Fluid Dynamics · Physics 2024-11-07 Srikumar Balasubramanian , Andres Goza

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

Computational Engineering, Finance, and Science · Computer Science 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu
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