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Variational autoencoders (VAEs), as an important aspect of generative models, have received a lot of research interests and reached many successful applications. However, it is always a challenge to achieve the consistency between the…

Machine Learning · Computer Science 2022-05-10 Xiaoyu Chen , Chen Gong , Qiang He , Xinwen Hou , Yu Liu

3D shape analysis is an important research topic in computer vision and graphics. While existing methods have generalized image-based deep learning to meshes using graph-based convolutions, the lack of an effective pooling operation…

Graphics · Computer Science 2019-08-08 Yu-Jie Yuan , Yu-Kun Lai , Jie Yang , Hongbo Fu , Lin Gao

Distributed learning and Edge AI necessitate efficient data processing, low-latency communication, decentralized model training, and stringent data privacy to facilitate real-time intelligence on edge devices while reducing dependency on…

Machine Learning · Computer Science 2025-07-08 Lucas Heublein , Simon Kocher , Tobias Feigl , Alexander Rügamer , Christopher Mutschler , Felix Ott

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

Genomics · Quantitative Biology 2017-11-15 Gregory P. Way , Casey S. Greene

We introduce a method combining variational autoencoders (VAEs) and deep metric learning to perform Bayesian optimisation (BO) over high-dimensional and structured input spaces. By adapting ideas from deep metric learning, we use label…

Diffusion models show promise for 3D molecular generation, but face a fundamental trade-off between sampling efficiency and conformational accuracy. While flow-based models are fast, they often produce geometrically inaccurate structures,…

Chemical Physics · Physics 2025-12-05 Peining Zhang , Jinbo Bi , Minghu Song

3D molecule generation is crucial for drug discovery and material science, requiring models to process complex multi-modalities, including atom types, chemical bonds, and 3D coordinates. A key challenge is integrating these modalities of…

Machine Learning · Computer Science 2025-10-14 Yanchen Luo , Zhiyuan Liu , Yi Zhao , Sihang Li , Hengxing Cai , Kenji Kawaguchi , Tat-Seng Chua , Yang Zhang , Xiang Wang

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based auto encoders have shown great potential in detecting anomalies in medical images. However, state-of-the-art…

Machine Learning · Computer Science 2018-12-17 David Zimmerer , Simon A. A. Kohl , Jens Petersen , Fabian Isensee , Klaus H. Maier-Hein

Recent work leverages Vision Foundation Models as image encoders to boost the generative performance of latent diffusion models (LDMs), as their semantic feature distributions are easy to learn. However, such semantic features often lack…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Siyu Liu , Chujie Qin , Hubery Yin , Qixin Yan , Zheng-Peng Duan , Chen Li , Jing Lyu , Chun-Le Guo , Chongyi Li

Visual generative models (e.g., diffusion models) typically operate in compressed latent spaces to balance training efficiency and sample quality. In parallel, there has been growing interest in leveraging high-quality pre-trained visual…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yuan Gao , Chen Chen , Tianrong Chen , Jiatao Gu

Recent video generation models largely rely on video autoencoders that compress pixel-space videos into latent representations. However, existing video autoencoders suffer from three major limitations: (1) fixed-rate compression that wastes…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Yao Teng , Minxuan Lin , Xian Liu , Shuai Wang , Xiao Yang , Xihui Liu

We propose an out-of-distribution detection method that combines density and restoration-based approaches using Vector-Quantized Variational Auto-Encoders (VQ-VAEs). The VQ-VAE model learns to encode images in a categorical latent space.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Sergio Naval Marimont , Giacomo Tarroni

We investigate the ability of Diffusion Variational Autoencoder ($\Delta$VAE) with unit sphere $\mathcal{S}^2$ as latent space to capture topological and geometrical structure and disentangle latent factors in datasets. For this, we…

Machine Learning · Computer Science 2024-09-04 Mahefa Ratsisetraina Ravelonanosy , Vlado Menkovski , Jacobus W. Portegies

The extraction of blood vessels has recently experienced a widespread interest in medical image analysis. Automatic vessel segmentation is highly desirable to guide clinicians in computer-assisted diagnosis, therapy or surgical planning.…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Amine Sadikine , Bogdan Badic , Jean-Pierre Tasu , Vincent Noblet , Dimitris Visvikis , Pierre-Henri Conze

VAEs, or variational autoencoders, are autoencoders that explicitly learn the distribution of the input image space rather than assuming no prior information about the distribution. This allows it to classify similar samples close to each…

Machine Learning · Computer Science 2023-02-08 Fareed Sheriff , Sameer Pai

Unsupervised representation learning via generative modeling is a staple to many computer vision applications in the absence of labeled data. Variational Autoencoders (VAEs) are powerful generative models that learn representations useful…

Machine Learning · Computer Science 2020-03-24 Riddhish Bhalodia , Iain Lee , Shireen Elhabian

Variational autoencoders (VAEs) are one class of generative probabilistic latent-variable models designed for inference based on known data. We develop three variations on VAEs by introducing a second parameterized encoder/decoder pair and,…

Machine Learning · Computer Science 2023-04-06 R. I. Cukier

The ability to extract generative parameters from high-dimensional fields of data in an unsupervised manner is a highly desirable yet unrealized goal in computational physics. This work explores the use of variational autoencoders (VAEs)…

Computational Physics · Physics 2021-11-16 Christian Jacobsen , Karthik Duraisamy

Learning latent representations that are simultaneously expressive, geometrically well-structured, and reliably calibrated remains a central challenge for Variational Autoencoders (VAEs). Standard VAEs typically assume a diagonal Gaussian…

Machine Learning · Computer Science 2025-12-02 Mehmet Can Yavuz

Despite recent successes in synthesizing faces and bedrooms, existing generative models struggle to capture more complex image types, potentially due to the oversimplification of their latent space constructions. To tackle this issue,…

Machine Learning · Computer Science 2018-03-13 Wenling Shang , Kihyuk Sohn , Yuandong Tian