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Related papers: Diffusion-Based Approaches in Medical Image Genera…

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Generative latent diffusion models have been established as state-of-the-art in data generation. One promising application is generation of realistic synthetic medical imaging data for open data sharing without compromising patient privacy.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Salman Ul Hassan Dar , Arman Ghanaat , Jannik Kahmann , Isabelle Ayx , Theano Papavassiliu , Stefan O. Schoenberg , Sandy Engelhardt

Machine learning has significantly advanced healthcare by aiding in disease prevention and treatment identification. However, accessing patient data can be challenging due to privacy concerns and strict regulations. Generating synthetic,…

Diffusion models were initially developed for text-to-image generation and are now being utilized to generate high quality synthetic images. Preceded by GANs, diffusion models have shown impressive results using various evaluation metrics.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Muhammad Usman Akbar , Wuhao Wang , Anders Eklund

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

As a new emerging and promising type of generative models, diffusion models have proven to outperform Generative Adversarial Networks (GANs) in multiple tasks, including image synthesis. In this work, we explore semantic image synthesis for…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Yan Zhuang , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Boah Kim , Ronald M. Summers

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

This study explores the utilization of Dermatoscopic synthetic data generated through stable diffusion models as a strategy for enhancing the robustness of machine learning model training. Synthetic data generation plays a pivotal role in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Muhammad Ali Farooq , Wang Yao , Michael Schukat , Mark A Little , Peter Corcoran

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Recent advances in synthetic imaging open up opportunities for obtaining additional data in the field of surgical imaging. This data can provide reliable supplements supporting surgical applications and decision-making through computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Simeon Allmendinger , Patrick Hemmer , Moritz Queisner , Igor Sauer , Leopold Müller , Johannes Jakubik , Michael Vössing , Niklas Kühl

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Generative image models have achieved remarkable progress in both natural and medical imaging. In the medical context, these techniques offer a potential solution to data scarcity-especially for low-prevalence anomalies that impair the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Gregory Schuit , Denis Parra , Cecilia Besa

Accurate single cell detection in brightfield microscopy is crucial for biological research, yet data scarcity and annotation bottlenecks limit the progress of deep learning methods. We investigate the use of unconditional models to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mario de Jesus da Graca , Jörg Dahlkemper , Peer Stelldinger

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Medical image analysis has become a prominent area where machine learning has been applied. However, high quality, publicly available data is limited either due to patient privacy laws or the time and cost required for experts to annotate…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Daniel Saragih , Atsuhiro Hibi , Pascal Tyrrell