Related papers: Transformer-based toxin-protein interaction analys…

Air pollution poses a serious threat to sustainable environmental conditions in the 21st century. Its importance in determining the health and living standards in urban settings is only expected to increase with time. Various factors…

Drug discovery remains time-consuming, labor-intensive, and expensive, often requiring years and substantial investment per drug candidate. Predicting compound-protein interactions (CPIs) is a critical component in this process, enabling…

Air pollution is a crucial issue affecting human health and livelihoods, as well as one of the barriers to economic and social growth. Forecasting air quality has become an increasingly important endeavor with significant social impacts,…

Discovering mutations enhancing protein-protein interactions (PPIs) is critical for advancing biomedical research and developing improved therapeutics. While machine learning approaches have substantially advanced the field, they often…

Air pollution represents a pivotal environmental challenge globally, playing a major role in climate change via greenhouse gas emissions and negatively affecting the health of billions. However predicting the spatial and temporal patterns…

The prediction of protein interactions (CPIs) is crucial for the in-silico screening step in drug discovery. Recently, many end-to-end representation learning methods using deep neural networks have achieved significantly better performance…

The influence of human activity own the earth's atmospheric composition has never been more pronounced. Anthropogenic pollution is in fact the largest effector of the observed evolving atmospheric composition (Wallace, 2006). PM2.5 is a…

Environmental contaminant exposure can pose significant risks to human health. Therefore, evaluating the impact of this exposure is of great importance; however, it is often difficult because both the molecular mechanism of disease and the…

Various machine-learning models, including deep neural network models, have already been developed to predict deleteriousness of missense (non-synonymous) mutations. Potential improvements to the current state of the art, however, may still…

This paper presents an engine able to predict jointly the real-time concentration of the main pollutants harming people's health: nitrogen dioxyde (NO2), ozone (O3) and particulate matter (PM2.5 and PM10, which are respectively the…

Air pollution remains a leading global health threat, with fine particulate matter (PM2.5) contributing to millions of premature deaths annually. Chemical transport models (CTMs) are essential tools for evaluating how emission controls…

Air pollution poses a serious threat to human health as well as economic development around the world. To meet the increasing demand for accurate predictions for air pollutions, we proposed a Deep Inferential Spatial-Temporal Network to…

Determining protein structures at an atomic level remains a significant challenge in structural biology. We introduce $\texttt{RecCrysFormer}$, a hybrid model that exploits the strengths of transformers with the aim of integrating…

Motivation: Identifying the molecular pathways more prone to disruption during a pathological process is a key task in network medicine and, more in general, in systems biology. Results: In this work we propose a pipeline that couples a…

Air pollution is a worldwide public health threat that can cause or exacerbate many illnesses, including respiratory disease, cardiovascular disease, and some cancers. However, epidemiological studies and public health decision-making are…

The spread of PM2.5 pollutants that endanger health is difficult to predict because it involves many atmospheric variables. These micron particles can spread rapidly from their source to residential areas, increasing the risk of respiratory…

The sustainability of urban environments is an increasingly relevant problem. Air pollution plays a key role in the degradation of the environment as well as the health of the citizens exposed to it. In this chapter we provide a review of…

Determining the structure of a protein has been a decades-long open question. A protein's three-dimensional structure often poses nontrivial computation costs, when classical simulation algorithms are utilized. Advances in the transformer…

Evaluating air quality interventions is confronted with the challenge of interference since interventions at a particular pollution source likely impact air quality and health at distant locations and air quality and health at any given…

Machine learning (ML) algorithms, particularly attention-based transformer models, have become indispensable for analyzing the vast data generated by particle physics experiments like ATLAS and CMS at the CERN LHC. Particle Transformer…