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Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagnosis of coronary artery disease. Current clinical protocols…

Medical Physics · Physics 2024-03-27 Nu Ri Choi , Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

Computed Tomography (CT) scans are the standard-of-care for the visualization and diagnosis of many clinical ailments, and are needed for the treatment planning of external beam radiotherapy. Unfortunately, the availability of CT scanners…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Yiran Sun , Hana Baroudi , Tucker Netherton , Laurence Court , Osama Mawlawi , Ashok Veeraraghavan , Guha Balakrishnan

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zezhang Yang , Zitong Yu , Nuri Choi , Janice Tania , Wenxuan Xue , Barry A. Siegel , Abhinav K. Jha

Deep-learning (DL)-based methods have shown significant promise in denoising myocardial perfusion SPECT images acquired at low dose. For clinical application of these methods, evaluation on clinical tasks is crucial. Typically, these…

Image and Video Processing · Electrical Eng. & Systems 2023-03-02 Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However, the lengthy scanning time in this imaging procedure can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Zezhang Yang , Zitong Yu , Nuri Choi , Abhinav K. Jha

Cardiovascular disease (CVD) is the leading cause of death worldwide, and myocardial perfusion imaging using SPECT has been widely used in the diagnosis of CVDs. The GE 530/570c dedicated cardiac SPECT scanners adopt a stationary geometry…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Huidong Xie , Bo Zhou , Xiongchao Chen , Xueqi Guo , Stephanie Thorn , Yi-Hwa Liu , Ge Wang , Albert Sinusas , Chi Liu

Low-field (LF) MRI scanners (<1T) are still prevalent in settings with limited resources or unreliable power supply. However, they often yield images with lower spatial resolution and contrast than high-field (HF) scanners. This quality…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Seunghoi Kim , Henry F. J. Tregidgo , Ahmed K. Eldaly , Matteo Figini , Daniel C. Alexander

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Kangbo Ma

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

Three-dimensional (3D) medical image enhancement, including denoising and super-resolution, is critical for clinical diagnosis in CT, PET, and MRI. Although diffusion models have shown remarkable success in 2D medical imaging, scaling them…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hongxu Jiang , Fei Li , Boxiao Yu , Ying Zhang , Kaleb Smith , Kuang Gong , Wei Shao

Attenuation artifacts remain a significant challenge in cardiac Myocardial Perfusion Imaging (MPI) using Single-Photon Emission Computed Tomography (SPECT), often compromising diagnostic accuracy and reducing clinical interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Trung Kien Pham , Hoang Minh Vu , Anh Duc Chu , Dac Thai Nguyen , Trung Thanh Nguyen , Thao Nguyen Truong , Mai Hong Son , Thanh Trung Nguyen , Phi Le Nguyen

The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Haoshen Wang , Zhentao Liu , Kaicong Sun , Xiaodong Wang , Dinggang Shen , Zhiming Cui

Accurate spatial correspondence between medical images is essential for longitudinal analysis, lesion tracking, and image-guided interventions. Medical image registration methods rely on local intensity-based similarity measures, which fail…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Xingyu Zhang , Anna Reithmeir , Fryderyk Kögl , Rickmer Braren , Julia A. Schnabel , Daniel M. Lang

We present DiffPortrait3D, a conditional diffusion model that is capable of synthesizing 3D-consistent photo-realistic novel views from as few as a single in-the-wild portrait. Specifically, given a single RGB input, we aim to synthesize…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Yuming Gu , You Xie , Hongyi Xu , Guoxian Song , Yichun Shi , Di Chang , Jing Yang , Linjie Luo

Diffusion-based sparse-view CT (SVCT) imaging has achieved remarkable advancements in recent years, thanks to its more stable generative capability. However, recovering reliable image content and visually consistent textures is still a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Tianqi Wang , Wenchao Du , Hongyu Yang
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