Related papers: VirusT5: Harnessing Large Language Models to Predi…
The rapid evolution and global impact of coronaviruses, notably SARS-CoV-1 and SARS-CoV-2, underscore the importance of understanding their molecular mechanisms in detail. This study focuses on the receptor-binding motif (RBM) within the…
Recent advancements in large language models (LLMs) have demonstrated their remarkable capabilities across various language tasks. Inspired by the success of text-to-text translation refinement, this paper investigates how LLMs can improve…
Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic…
The transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of paramount importance to the controlling and combating of coronavirus disease 2019 (COVID-19) pandemic. Currently, near 15,000 SARS-CoV-2…
Software languages evolve over time for various reasons, such as the addition of new features. When the language's grammar definition evolves, textual instances that originally conformed to the grammar become outdated. For DSLs in a…
The importance of understanding SARS-CoV-2 evolution cannot be overemphasized. Recent studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 evolution, which favors mutations that strengthen viral infectivity. We…
The interpretation of multi-temporal remote sensing imagery is critical for monitoring Earth's dynamic processes-yet previous change detection methods, which produce binary or semantic masks, fall short of providing human-readable insights…
Evolution, the engine behind the survival and growth of life on Earth, operates through the population-based process of reproduction. Inspired by this principle, this paper formally defines a newly emerging problem -- the population-based…
Recent advancements in large language models (LLMs) have revolutionized various domains, bringing significant progress and new opportunities. Despite progress in speech-related tasks, LLMs have not been sufficiently explored in multi-talker…
In this work, we derive a system of Boltzmann-type equations to describe the spread of SARS-CoV-2 virus at the microscopic scale, that is by modeling the human-to-human mechanisms of transmission. To this end, we consider two populations,…
We systematically study how three large language models with code capabilities - CodeT5, Codex, and ChatGPT - generalize to out-of-domain data. We consider two fundamental applications - code summarization, and code generation. We split…
Forecasting the change in the distribution of viral variants is crucial for therapeutic design and disease surveillance. This task poses significant modeling challenges due to the sharp differences in virus distributions across…
The impressive performance of large language models (LLMs) has led to their consideration as models of human language processing. Instead, we suggest that the success of LLMs arises from the flexibility of the transformer learning…
The rapid spread of the COVID-19 pandemic has resulted in an unprecedented amount of sequence data of the SARS-CoV-2 genome -- millions of sequences and counting. This amount of data, while being orders of magnitude beyond the capacity of…
Large Language Models (LLMs) exhibit world knowledge and inference capabilities, making them powerful tools for various applications. This paper proposes a feedback loop mechanism that leverages these capabilities to tune Evolution…
Large language models (LLMs), known for their exceptional reasoning capabilities, generalizability, and fluency across diverse domains, present a promising avenue for enhancing speech-related tasks. In this paper, we focus on integrating…
Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…
Given the great success of large language models (LLMs) across various tasks, in this paper, we introduce LLM-ST, a novel and effective speech translation model constructed upon a pre-trained LLM. By integrating the large language model…
Machine Translation (MT) has greatly advanced over the years due to the developments in deep neural networks. However, the emergence of Large Language Models (LLMs) like GPT-4 and ChatGPT is introducing a new phase in the MT domain. In this…
Large language models (LLMs) have significantly advanced various natural language processing (NLP) tasks. Recent research indicates that moderately-sized LLMs often outperform larger ones after task-specific fine-tuning. This study focuses…