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We introduce HyperMorph, a framework that facilitates efficient hyperparameter tuning in learning-based deformable image registration. Classical registration algorithms perform an iterative pair-wise optimization to compute a deformation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Andrew Hoopes , Malte Hoffmann , Douglas N. Greve , Bruce Fischl , John Guttag , Adrian V. Dalca

In current biological and medical research, statistical shape modeling (SSM) provides an essential framework for the characterization of anatomy/morphology. Such analysis is often driven by the identification of a relatively small number of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Riddhish Bhalodia , Shireen Elhabian , Ladislav Kavan , Ross Whitaker

Deformable medical image registration is a crucial aspect of medical image analysis. In recent years, researchers have begun leveraging auxiliary tasks (such as supervised segmentation) to provide anatomical structure information for the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hongchao Zhou , Shunbo Hu

Deformable medical image registration is traditionally formulated as an optimization problem. While classical methods solve this problem iteratively, recent learning-based approaches use recurrent neural networks (RNNs) to mimic this…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Yi Zhang , Yidong Zhao , Qian Tao

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

We revisit Deep Linear Discriminant Analysis (Deep LDA) from a likelihood-based perspective. While classical LDA is a simple Gaussian model with linear decision boundaries, attaching an LDA head to a neural encoder raises the question of…

Machine Learning · Statistics 2026-02-23 Maxat Tezekbayev , Arman Bolatov , Zhenisbek Assylbekov

We study the problem of registration for medical CT images from a novel perspective -- the sensitivity to degree of deformations in CT images. Although some learning-based methods have shown success in terms of average accuracy, their…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Xinyu Zhao , Sa Huang , Wei Pang , You Zhou

Anomaly detection (AD) plays a vital role across a wide range of domains, but its performance might deteriorate when applied to target domains with limited data. Domain Adaptation (DA) offers a solution by transferring knowledge from a…

Machine Learning · Statistics 2025-08-12 Tran Tuan Kiet , Nguyen Thang Loi , Vo Nguyen Le Duy

Ultrasound Elastography aims to determine the mechanical properties of the tissue by monitoring tissue deformation due to internal or external forces. Tissue deformations are estimated from ultrasound radio frequency (RF) signals and are…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Abdelrahman Zayed , Hassan Rivaz

Recent successes in deep learning based deformable image registration (DIR) methods have demonstrated that complex deformation can be learnt directly from data while reducing computation time when compared to traditional methods. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Sharib Ali , Jens Rittscher

This paper proposes a novel deep subspace clustering approach which uses convolutional autoencoders to transform input images into new representations lying on a union of linear subspaces. The first contribution of our work is to insert…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Mohsen Kheirandishfard , Fariba Zohrizadeh , Farhad Kamangar

Degenerative spinal pathologies are highly prevalent among the elderly population. Timely diagnosis of osteoporotic fractures and other degenerative deformities facilitates proactive measures to mitigate the risk of severe back pain and…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Hellena Hempe , Alexander Bigalke , Mattias P. Heinrich

Most existing deep learning-based registration methods are trained on single-type images to address same-domain tasks.However, cross-domain deformable registration remains challenging.We argue that the tailor-made matching criteria in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Zhuoyuan Wang , Haiqiao Wang , Yi Wang

Low-rank adaptation (LoRA) has been widely adopted as a parameter-efficient technique for fine-tuning large-scale pre-trained models. However, it still lags behind full fine-tuning in performance, partly due to its insufficient exploitation…

Machine Learning · Computer Science 2026-04-03 Zhizhong Li , Sina Sajadmanesh , Jingtao Li , Lingjuan Lyu

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Deformable image registration (alignment) is highly sought after in numerous clinical applications, such as computer aided diagnosis and disease progression analysis. Deep Convolutional Neural Network (DCNN)-based image registration methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Christian Wagner , Xin Chen

Document layout analysis (DLA) is crucial for understanding the physical layout and logical structure of documents, serving information retrieval, document summarization, knowledge extraction, etc. However, previous studies have typically…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Jiawei Wang , Kai Hu , Qiang Huo

We present a postprocessing layer for deformable image registration to make a registration field more diffeomorphic by encouraging Jacobians of the transformation to be positive. Diffeomorphic image registration is important for medical…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Soumyadeep Pal , Matthew Tennant , Nilanjan Ray

Proper segmentation of organs-at-risk is important for radiation therapy, surgical planning, and diagnostic decision-making in medical image analysis. While deep learning-based segmentation architectures have made significant progress, they…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Riad Hassan , M. Rubaiyat Hossain Mondal , Sheikh Iqbal Ahamed , Fahad Mostafa , Md Mostafijur Rahman

Medical images are acquired at high resolutions with large fields of view in order to capture fine-grained features necessary for clinical decision-making. Consequently, training deep learning models on medical images can incur large…