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Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong

The rapid advancements of computing technology facilitate the development of diverse deep learning applications. Unfortunately, the efficiency of parallel computing infrastructures varies widely with neural network models, which hinders the…

Machine Learning · Computer Science 2020-12-04 Chuan-Chi Wang , Ying-Chiao Liao , Chia-Heng Tu , Ming-Chang Kao , Wen-Yew Liang , Shih-Hao Hung

Deep energy-based models are powerful, but pose challenges for learning and inference (Belanger and McCallum, 2016). Tu and Gimpel (2018) developed an efficient framework for energy-based models by training "inference networks" to…

Computation and Language · Computer Science 2020-10-13 Lifu Tu , Richard Yuanzhe Pang , Kevin Gimpel

Recent work explored the potential of large-scale Transformer-based pre-trained models, especially Pre-trained Language Models (PLMs) in natural language processing. This raises many concerns from various perspectives, e.g., financial costs…

Computation and Language · Computer Science 2022-05-23 Yuxin Ren , Benyou Wang , Lifeng Shang , Xin Jiang , Qun Liu

In urban computing, precise and swift forecasting of multivariate time series data from traffic networks is crucial. This data incorporates additional spatial contexts such as sensor placements and road network layouts, and exhibits complex…

Machine Learning · Computer Science 2024-12-19 Tongtong Zhang , Zhiyong Cui , Bingzhang Wang , Yilong Ren , Haiyang Yu , Pan Deng , Yinhai Wang

Network traffic prediction techniques have attracted much attention since they are valuable for network congestion control and user experience improvement. While existing prediction techniques can achieve favorable performance when there is…

Networking and Internet Architecture · Computer Science 2025-05-29 Hui Ma , Kai Yang

Fueled by their remarkable ability to tackle diverse tasks across multiple domains, large language models (LLMs) have grown at an unprecedented rate, with some recent models containing trillions of parameters. This growth is accompanied by…

Machine Learning · Computer Science 2025-05-30 Athanasios Glentis , Jiaxiang Li , Qiulin Shang , Andi Han , Ioannis Tsaknakis , Quan Wei , Mingyi Hong

One very important hyperparameter for training deep neural networks is the learning rate schedule of the optimizer. The choice of learning rate schedule determines the computational cost of getting close to a minima, how close you actually…

Machine Learning · Computer Science 2021-06-01 Nikhil Iyer , V Thejas , Nipun Kwatra , Ramachandran Ramjee , Muthian Sivathanu

In this work we explore the application of deep neural networks to the optimization of atomic layer deposition processes based on thickness values obtained at different points of an ALD reactor. We introduce a dataset designed to train…

Machine Learning · Computer Science 2024-06-19 Angel Yanguas-Gil , Jeffrey W. Elam

In semi-supervised semantic segmentation, the Mean Teacher- and co-training-based approaches are employed to mitigate confirmation bias and coupling problems. However, despite their high performance, these approaches frequently involve…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Wooseok Shin , Hyun Joon Park , Jin Sob Kim , Juan Yun , Se Hong Park , Sung Won Han

Accurate load forecasting is crucial for maintaining the power balance between generators and consumers,particularly with the increasing integration of renewable energy sources, which introduce significant intermittent volatility. With the…

Systems and Control · Electrical Eng. & Systems 2024-09-04 Mingyang Gao , Suyang Zhou , Wei Gu , Zhi Wu , Haiquan Liu , Aihua Zhou

Recurrent and convolutional neural networks are the most common architectures used for time series forecasting in deep learning literature. These networks use parameter sharing by repeating a set of fixed architectures with fixed parameters…

Machine Learning · Computer Science 2020-11-30 Joel Janek Dabrowski , YiFan Zhang , Ashfaqur Rahman

The fast growing capabilities of large-scale deep learning models, such as Bert, GPT and ViT, are revolutionizing the landscape of NLP, CV and many other domains. Training such models, however, poses an unprecedented demand for computing…

Machine Learning · Computer Science 2024-04-15 Longwei Zou , Han Zhang , Yangdong Deng

Pre-trained Large Language Models (LLMs) encapsulate large amounts of knowledge and take enormous amounts of compute to train. We make use of this resource, together with the observation that LLMs are able to transfer knowledge and…

Machine Learning · Computer Science 2025-01-14 Malcolm L. Wolff , Shenghao Yang , Kari Torkkola , Michael W. Mahoney

The application of TensorFlow pre-trained models in deep learning is explored, with an emphasis on practical guidance for tasks such as image classification and object detection. The study covers modern architectures, including ResNet,…

Language models are increasingly used not only as standalone predictors but also as components in larger inference systems, from test-time reasoning to multi-model collaboration. We study language model networks, where pre-trained language…

Artificial Intelligence · Computer Science 2026-05-14 Shiguang Wu , Yaqing Wang , Quanming Yao

Ensembles of deep neural networks significantly improve generalization accuracy. However, training neural network ensembles requires a large amount of computational resources and time. State-of-the-art approaches either train all networks…

Machine Learning · Computer Science 2020-03-10 Abdul Wasay , Brian Hentschel , Yuze Liao , Sanyuan Chen , Stratos Idreos

We tackle the problem of predicting the number of optimization steps that a pre-trained deep network needs to converge to a given value of the loss function. To do so, we leverage the fact that the training dynamics of a deep network during…

Machine Learning · Computer Science 2020-08-31 Luca Zancato , Alessandro Achille , Avinash Ravichandran , Rahul Bhotika , Stefano Soatto

The process of training a deep neural network is characterized by significant time requirements and associated costs. Although researchers have made considerable progress in this area, further work is still required due to resource…

Machine Learning · Computer Science 2023-12-29 Sahil Nokhwal , Priyanka Chilakalapudi , Preeti Donekal , Suman Nokhwal , Saurabh Pahune , Ankit Chaudhary

Ternary quantization has emerged as a powerful technique for reducing both computational and memory footprint of large language models (LLM), enabling efficient real-time inference deployment without significantly compromising model…

Hardware Architecture · Computer Science 2025-09-18 Zhirui Huang , Rui Ma , Shijie Cao , Ran Shu , Ian Wang , Ting Cao , Chixiao Chen , Yongqiang Xiong
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