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Nuclei segmentation is one of the important tasks for whole slide image analysis in digital pathology. With the drastic advance of deep learning, recent deep networks have demonstrated successful performance of the nuclei segmentation task.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Inwan Yoo , Donggeun Yoo , Kyunghyun Paeng

We propose a novel semi-supervised image segmentation method that simultaneously optimizes a supervised segmentation and an unsupervised reconstruction objectives. The reconstruction objective uses an attention mechanism that separates the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Shuai Chen , Gerda Bortsova , Antonio Garcia-Uceda Juarez , Gijs van Tulder , Marleen de Bruijne

We propose a method for effectively utilizing weakly annotated image data in an object detection tasks of breast ultrasound images. Given the problem setting where a small, strongly annotated dataset and a large, weakly annotated dataset…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 JooYeol Yun , JungWoo Oh , IlDong Yun

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Accurate segmentation of organelle instances, e.g., mitochondria, is essential for electron microscopy analysis. Despite the outstanding performance of fully supervised methods, they highly rely on sufficient per-pixel annotated data and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Dafei Qiu , Jiajin Yi , Jialin Peng

Deep neural networks are highly effective when a large number of labeled samples are available but fail with few-shot classification tasks. Recently, meta-learning methods have received much attention, which train a meta-learner on massive…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Yucan Zhou , Yu Wang , Jianfei Cai , Yu Zhou , Qinghua Hu , Weiping Wang

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

The expansion of artificial intelligence (AI) in pathology tasks has intensified the demand for doctors' annotations in AI development. However, collecting high-quality annotations from doctors is costly and time-consuming, creating a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Hongyan Gu , Zihan Yan , Ayesha Alvi , Brandon Day , Chunxu Yang , Zida Wu , Shino Magaki , Mohammad Haeri , Xiang 'Anthony' Chen

Deep learning highly relies on the amount of annotated data. However, annotating medical images is extremely laborious and expensive. To this end, self-supervised learning (SSL), as a potential solution for deficient annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Jiuwen Zhu , Yuexiang Li , Yifan Hu , S. Kevin Zhou

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

A large labeled dataset is a key to the success of supervised deep learning, but for medical image segmentation, it is highly challenging to obtain sufficient annotated images for model training. In many scenarios, unannotated images are…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Hao Zheng , Jun Han , Hongxiao Wang , Lin Yang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Medical image segmentation has been significantly advanced by deep learning (DL) techniques, though the data scarcity inherent in medical applications poses a great challenge to DL-based segmentation methods. Self-supervised learning offers…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Binyan Hu , A. K. Qin

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

Digital pathology tasks have benefited greatly from modern deep learning algorithms. However, their need for large quantities of annotated data has been identified as a key challenge. This need for data can be countered by using…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Jacob Carse , Frank Carey , Stephen McKenna

Weakly supervised LiDAR semantic segmentation has made significant strides with limited labeled data. However, most existing methods focus on the network training under weak supervision, while efficient annotation strategies remain largely…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Yilong Chen , Zongyi Xu , xiaoshui Huang , Ruicheng Zhang , Xinqi Jiang , Xinbo Gao