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Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Mathematical reasoning continues to be a critical challenge in large language model (LLM) development with significant interest. However, most of the cutting-edge progress in mathematical reasoning with LLMs has become \emph{closed-source}…

Computation and Language · Computer Science 2024-10-08 Shubham Toshniwal , Wei Du , Ivan Moshkov , Branislav Kisacanin , Alexan Ayrapetyan , Igor Gitman

This survey explores the transformative impact of foundation models (FMs) in artificial intelligence, focusing on their integration with federated learning (FL) for advancing biomedical research. Foundation models such as ChatGPT, LLaMa,…

Machine Learning · Computer Science 2024-05-14 Xingyu Li , Lu Peng , Yuping Wang , Weihua Zhang

The growing disparity between the exponential scaling of computational resources and the finite growth of high-quality text data now constrains conventional scaling approaches for large language models (LLMs). To address this challenge, we…

Recent advances in Large Language Models (LLMs) have significantly enhanced their capabilities, highlighting the need for comprehensive evaluation frameworks that extend beyond task-specific benchmarks. However, existing benchmarks often…

Computation and Language · Computer Science 2025-09-30 Haosi Mo , Xinyu Ma , Xuebo Liu , Derek F. Wong , Yu Li , Jie Liu , Min Zhang

The rapid advancement of Artificial Intelligence has resulted in the advent of Large Language Models (LLMs) with the capacity to produce text that closely resembles human communication. These models have been seamlessly integrated into…

Machine Learning · Computer Science 2025-02-04 Zenon Lamprou , Yashar Moshfeghi

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

Computation and Language · Computer Science 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Computation and Language · Computer Science 2021-12-16 Robert Tinn , Hao Cheng , Yu Gu , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Large language models (LLMs) are increasingly used to create content in regulated domains such as pharmaceuticals, where outputs must be scientifically accurate and legally compliant. Manual quality control (QC) is slow, error prone, and…

Machine Learning · Computer Science 2026-02-13 Suyash Mishra , Qiang Li , Anubhav Girdhar

Large language models (LLMs) show increasing promise in medical applications, but their ability to detect and correct errors in clinical texts -- a prerequisite for safe deployment -- remains under-evaluated, particularly beyond English. We…

Computation and Language · Computer Science 2025-11-04 Naoto Iwase , Hiroki Okuyama , Junichiro Iwasawa

Adapting pretrained language models to novel domains, such as clinical applications, traditionally involves retraining their entire set of parameters. Parameter-Efficient Fine-Tuning (PEFT) techniques for fine-tuning language models…

Computation and Language · Computer Science 2024-06-11 Aryo Pradipta Gema , Pasquale Minervini , Luke Daines , Tom Hope , Beatrice Alex

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters. LLMs have stirred up much interest among…

Computation and Language · Computer Science 2023-08-01 Hanyao Huang , Ou Zheng , Dongdong Wang , Jiayi Yin , Zijin Wang , Shengxuan Ding , Heng Yin , Chuan Xu , Renjie Yang , Qian Zheng , Bing Shi

This paper presents a comprehensive survey of ChatGPT-related (GPT-3.5 and GPT-4) research, state-of-the-art large language models (LLM) from the GPT series, and their prospective applications across diverse domains. Indeed, key innovations…

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Adapting large language models (LLMs) to new languages typically involves continual pre-training (CT) followed by supervised fine-tuning (SFT). However, this CT-then-SFT approach struggles with limited data in the context of low-resource…

Computation and Language · Computer Science 2025-02-10 Mingxu Tao , Chen Zhang , Quzhe Huang , Tianyao Ma , Songfang Huang , Dongyan Zhao , Yansong Feng

Large Language Models (LLMs) have transformed software development by enabling code generation, automated debugging, and complex reasoning. However, their continued advancement is constrained by the scarcity of high-quality, publicly…

Software Engineering · Computer Science 2025-08-11 Wasi Uddin Ahmad , Aleksander Ficek , Mehrzad Samadi , Jocelyn Huang , Vahid Noroozi , Somshubra Majumdar , Boris Ginsburg

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Recently, data-driven task-oriented dialogue systems have achieved promising performance in English. However, developing dialogue systems that support low-resource languages remains a long-standing challenge due to the absence of…

Computation and Language · Computer Science 2019-11-22 Zihan Liu , Genta Indra Winata , Zhaojiang Lin , Peng Xu , Pascale Fung
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