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Related papers: Velocity Jumps for Molecular Dynamics

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In this article, we present the potential benefits of incorporating jumps into the dynamics of digital memcomputing machines (DMMs), which have been developed to address complex optimization problems. We illustrate the potential speed…

Emerging Technologies · Computer Science 2026-02-03 Yuriy V. Pershin

A new Langevin-Verlet thermostat that preserves the fluctuation-dissipation relationship for discrete time steps, is applied to molecular modeling and tested against several popular suites (AMBER, GROMACS, LAMMPS) using a small molecule as…

Materials Science · Physics 2013-12-17 Niels Grønbech-Jensen , Natha Robert Hayre , Oded Farago

To accelerate the thermal equilibrium sampling of multi-level quantum systems, the infinite swapping limit of a recently proposed multi-level ring polymer representation is investigated. In the infinite swapping limit, the ring polymer…

Chemical Physics · Physics 2018-03-14 Jianfeng Lu , Zhennan Zhou

Langevin and Brownian simulations play a prominent role in computational research, and state of the art integration algorithms provide trajectories with different stability ranges and accuracy in reproducing statistical averages. The…

Computational Physics · Physics 2025-01-03 Bogdan Tanygin , Simone Melchionna

Molecular dynamics (MD) simulation is a widely used technique to simulate molecular systems, most commonly at the all-atom resolution where equations of motion are integrated with timesteps on the order of femtoseconds…

Simulating the long-timescale dynamics of biomolecules is a central challenge in computational science. While enhanced sampling methods can accelerate these simulations, they rely on pre-defined collective variables that are often difficult…

Biomolecules · Quantitative Biology 2025-12-01 Aditya Sengar , Jiying Zhang , Pierre Vandergheynst , Patrick Barth

Multi-depot vehicle routing problems (MDVRPs) are prevalent in a variety of practical applications. However, they are computationally challenging to solve due to their inherent complexity. This paper proposes an effective hybrid algorithm…

Robotics · Computer Science 2026-05-08 Zhenyu Lei , Jin-Kao Hao

As intelligent systems become increasingly important in our daily lives, new ways of interaction are needed. Classical user interfaces pose issues for the physically impaired and are partially not practical or convenient. Gesture…

Robotics · Computer Science 2024-01-31 Lea Steffen , Thomas Trapp , Arne Roennau , Rüdiger Dillmann

Quantum nuclear dynamics with wavepacket time-evolution is classically intractable and viewed as a promising avenue for quantum information processing. Here, we use an IonQ 11-qubit trapped-ion quantum computer, Harmony, to study the…

Quantum Physics · Physics 2024-12-05 Anurag Dwivedi , A. J. Rasmusson , Philip Richerme , Srinivasan S. Iyengar

There exist several methods for simulating biological and physical systems as represented by chemical reaction networks. Systems with low numbers of particles are frequently modelled as discrete-state Markov jump processes and are typically…

Quantitative Methods · Quantitative Biology 2022-10-24 Joshua C. Kynaston , Christian A Yates , Anna Hekkink , Chris Guiver

Modern graphics processing units (GPUs) provide impressive computing resources, which can be accessed conveniently through the CUDA programming interface. We describe how GPUs can be used to considerably speed up molecular dynamics (MD)…

Computational Physics · Physics 2011-04-08 Peter H. Colberg , Felix Höfling

We prove that a denoising diffusion sampler equipped with a sequential bias across the batch dimension is exactly an Euler-Maruyama integrator for overdamped Langevin dynamics. Each reverse denoising step, with its associated spring…

Machine Learning · Computer Science 2025-12-01 Justin Diamond , Markus Lill

Langevin diffusion is a powerful method for nonconvex optimization, which enables the escape from local minima by injecting noise into the gradient. In particular, the temperature parameter controlling the noise level gives rise to a…

Machine Learning · Statistics 2020-07-07 Yi Chen , Jinglin Chen , Jing Dong , Jian Peng , Zhaoran Wang

The Rouse model with harmonic springs and the Langevin equation (Langevin-Rouse model) is widely used to describe the linear viscoelasticity of unentangled polymer melts. A similar model, in which the Langevin equation is replaced by…

Soft Condensed Matter · Physics 2024-03-19 Takashi Uneyama

We present a quantum-assisted generative algorithm for synthetic tracks of Lagrangian tracer particles in a turbulent shear flow. The parallelism and sampling properties of quantum algorithms are used to build and optimize a parametric…

Fluid Dynamics · Physics 2025-08-28 Julia Ingelmann , Fabian Schindler , Jörg Schumacher

Machine learning potentials have emerged as a means to enhance the accuracy of biomolecular simulations. However, their application is constrained by the significant computational cost arising from the vast number of parameters compared to…

Mixture-of-Experts (MoE) has been adopted by many leading large models to reduce computational requirements. However, frequent inter-GPU communication in MoE expert parallelism (EP) becomes a performance challenge. We observe substantial…

Hardware Architecture · Computer Science 2026-05-08 Qijun Zhang , Chen Zhang , Zhuoshan Zhou , Haibo Wang , Zhe Zhou , Zhipeng Tu , Guangyu Sun , Zhiyao Xie , Yijia Diao , Zhigang Ji , Jingwen Leng , Guanghui He , Minyi Guo

Piecewise-deterministic Markov processes (PDMPs) offer a powerful stochastic modeling framework that combines deterministic trajectories with random perturbations at random times. Estimating their local characteristics (particularly the…

Methodology · Statistics 2025-12-29 Romain Azaïs , Solune Denis

Molecular dynamics (MD) simulation based on Langevin equation has been widely used in the study of structural, thermal properties of matters in difference phases. Normally, the atomic dynamics are described by classical equations of motion…

Mesoscale and Nanoscale Physics · Physics 2018-02-06 Jing-Tao Lü , Bing-Zhong Hu , Per Hedegård , Mads Brandbyge

Despite the fact that visuomotor-based policies obtained via imitation learning demonstrate good performances in complex manipulation tasks, they usually struggle to achieve the same accuracy and speed as traditional control based methods.…

Robotics · Computer Science 2025-12-05 Jonne Van Haastregt , Bastian Orthmann , Michael C. Welle , Yuchong Zhang , Danica Kragic