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Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right…

Tissues and Organs · Quantitative Biology 2019-12-11 Amanda L. Colunga , Karam G. Kim , N. Payton Woodall , Todd F. Dardas , John H. Gennari , Mette S. Olufsen , Brian E. Carlson

We propose inferential tools for functional linear quantile regression where the conditional quantile of a scalar response is assumed to be a linear functional of a functional covariate. In contrast to conventional approaches, we employ…

Statistics Theory · Mathematics 2022-02-25 Peijun Sang , Zuofeng Shang , Pang Du

Objective: When patients develop acute respiratory failure, accurately identifying the underlying etiology is essential for determining the best treatment. However, differentiating between common medical diagnoses can be challenging in…

Machine Learning · Computer Science 2022-04-21 Sarah Jabbour , David Fouhey , Ella Kazerooni , Jenna Wiens , Michael W Sjoding

In this paper we propose a multivariate ordinal regression model which allows the joint modeling of three-dimensional panel data containing both repeated and multiple measurements for a collection of subjects. This is achieved by a…

Methodology · Statistics 2024-02-02 Laura Vana-Gür

As medical devices become more complex, they routinely collect extensive and complicated data. While classical regressions typically examine the relationship between an outcome and a vector of predictors, it becomes imperative to identify…

Methodology · Statistics 2024-05-16 Huaqing Jin , Fei Jiang

In this study, we propose a function-on-function linear quantile regression model that allows for more than one functional predictor to establish a more flexible and robust approach. The proposed model is first transformed into a…

Methodology · Statistics 2021-11-11 Ufuk Beyaztas , Han Lin Shang

Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models…

Accurate characterisation of visual attributes such as spiculation, lobulation, and calcification of lung nodules is critical in cancer management. The characterisation of these attributes is often subjective, which may lead to high inter-…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

COVID-19 image analysis has mostly focused on diagnostic tasks using single timepoint scans acquired upon disease presentation or admission. We present a deep learning-based approach to predict lung infiltrate progression from serial chest…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Aishik Konwer , Joseph Bae , Gagandeep Singh , Rishabh Gattu , Syed Ali , Jeremy Green , Tej Phatak , Prateek Prasanna

Radiation therapy of thoracic and abdominal tumors requires incorporating the respiratory motion into treatments. To precisely account for the patient respiratory motions and predict the respiratory signals, a generalized model for…

Medical Physics · Physics 2019-05-22 Hui Lin , Chengyu Shi , Brian Wang , Maria F. Chan , Xiaoli Tang , Wei Ji

Robust quantification of pulmonary emphysema on computed tomography (CT) remains challenging for large-scale research studies that involve scans from different scanner types and for translation to clinical scans. Existing studies have…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Xuzhe Zhang , Elsa D. Angelini , Eric A. Hoffman , Karol E. Watson , Benjamin M. Smith , R. Graham Barr , Andrew F. Laine

This paper addresses estimation in a longitudinal regression model for association between a scalar outcome and a set of longitudinally-collected functional covariates or predictor curves. The framework consists of estimating a time-varying…

Applications · Statistics 2020-06-30 Madan G. Kundu , Jaroslaw Harezlak , Timothy W. Randolph

Hypothesis testing procedures are developed to assess linear operator constraints in function-on-scalar regression when incomplete functional responses are observed. The approach enables statistical inferences about the shape and other…

Methodology · Statistics 2022-12-06 Yeonjoo Park , Kyunghee Han , Douglas G. Simpson

Acute respiratory distress syndrome (ARDS) is a severe condition characterized by lung inflammation and respiratory failure, with a high mortality rate of approximately 40%. Traditional imaging methods, such as chest X-rays, provide only…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Siyeop Yoon , Yujin Oh , Xiang Li , Yi Xin , Maurizio Cereda , Quanzheng Li

This paper is motivated by medical studies in which the same patients with multiple sclerosis are examined at several successive visits and described by fractional anisotropy tract profiles, which can be represented as functions. Since the…

Methodology · Statistics 2023-06-07 Katarzyna Kuryło , Łukasz Smaga

The linear regression model is widely used in the biomedical and social sciences as well as in policy and business research to adjust for covariates and estimate the average effects of treatments. Behind every causal inference endeavor…

Methodology · Statistics 2024-04-23 Ambarish Chattopadhyay , Noah Greifer , Jose R. Zubizarreta

Lung infections, particularly pneumonia, pose serious health risks that can escalate rapidly, especially during pandemics. Accurate AI-based severity prediction from medical imaging is essential to support timely clinical decisions and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Bouthaina Slika , Fadi Dornaika , Fares Bougourzi , Karim Hammoudi

This paper develops a novel spatial quantile function-on-scalar regression model, which studies the conditional spatial distribution of a high-dimensional functional response given scalar predictors. With the strength of both quantile…

Methodology · Statistics 2020-12-22 Zhengwu Zhang , Xiao Wang , Linglong Kong , Hongtu Zhu

The 3D simulation model of the lung was established by using the reconstruction method. A computer aided pulmonary nodule detection model was constructed. The process iterates over the images to refine the lung nodule recognition model…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yutian Yang , Hongjie Qiu , Yulu Gong , Xiaoyi Liu , Yang Lin , Muqing Li

We demonstrate a simple strategy to cope with missing data in sequential inputs, addressing the task of multilabel classification of diagnoses given clinical time series. Collected from the pediatric intensive care unit (PICU) at Children's…

Machine Learning · Computer Science 2016-11-14 Zachary C. Lipton , David C. Kale , Randall Wetzel