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In observational studies, adjusting for confounders is required if a treatment comparison is planned. A crude comparison of the primary endpoint without covariate adjustment will suffer from biases, and the addition of regression models…

Methodology · Statistics 2026-02-11 Shiyu Shu , Toshimitsu Hamasaki , Scott Evans , Lauren Komarow , David van Duin , Guoqing Diao

In regression models fitted to data from complex survey designs, sampling weights often incorporate non-essential variation, inflating variance estimates. Stabilized weights mitigate this issue by adjusting sampling weights to account for…

Methodology · Statistics 2026-05-18 Tong Chen , Joshua Slone , Gustavo Amorim , Pamela A. Shaw , Bryan E. Shepherd , Thomas Lumley

Widely used methods and software for group sequential tests of a null hypothesis of no treatment difference that allow for early stopping of a clinical trial depend primarily on the fact that sequentially-computed test statistics have the…

Methodology · Statistics 2025-06-19 Anastasios A. Tsiatis , Marie Davidian

Robust tests of general composite hypothesis under non-identically distributed observations is always a challenge. Ghosh and Basu (2018, Statistica Sinica, 28, 1133--1155) have proposed a new class of test statistics for such problems based…

Statistics Theory · Mathematics 2019-01-08 Abhik Ghosh , Ayanendranath Basu

A formal likelihood ratio hypothesis test for the validity of a parametric regression function is proposed, using a large-dimensional, nonparametric double cone alternative. For example, the test against a constant function uses the…

Methodology · Statistics 2014-06-30 Bodhisattva Sen , Mary Meyer

In multigroup data settings with small within-group sample sizes, standard $F$-tests of group-specific linear hypotheses can have low power, particularly if the within-group sample sizes are not large relative to the number of explanatory…

Methodology · Statistics 2022-03-25 Andrew McCormack , Peter Hoff

In the field of NLP, Large Language Models (LLMs) have markedly enhanced performance across a variety of tasks. However, the comprehensive evaluation of LLMs remains an inevitable challenge for the community. Recently, the adoption of…

Computation and Language · Computer Science 2024-12-09 Haochun Wang , Sendong Zhao , Zewen Qiang , Nuwa Xi , Bing Qin , Ting Liu

In variable or graph selection problems, finding a right-sized model or controlling the number of false positives is notoriously difficult. Recently, a meta-algorithm called Stability Selection was proposed that can provide reliable…

Machine Learning · Statistics 2017-12-14 George Philipp , Seunghak Lee , Eric P. Xing

Low-rank matrix recovery problems arise naturally as mathematical formulations of various inverse problems, such as matrix completion, blind deconvolution, and phase retrieval. Over the last two decades, a number of works have rigorously…

Information Theory · Computer Science 2021-06-09 Tim Fuchs , David Gross , Peter Jung , Felix Krahmer , Richard Kueng , Dominik Stöger

Rare and Weak models for multiple hypothesis testing assume that only a small proportion of the tested hypotheses concern non-null effects and the individual effects are only moderately large, so they generally do not stand out…

Statistics Theory · Mathematics 2025-02-20 Alon Kipnis

Many testing problems are readily amenable to randomised tests such as those employing data splitting. However despite their usefulness in principle, randomised tests have obvious drawbacks. Firstly, two analyses of the same dataset may…

Methodology · Statistics 2024-09-05 F. Richard Guo , Rajen D. Shah

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in…

Methodology · Statistics 2021-05-27 Siyun Yang , Fan Li , Laine E. Thomas , Fan Li

It is well known that the conventional cumulative sum (CUSUM) test suffers from low power and large detection delay. In order to improve the power of the test, we propose two alternative statistics. The backward CUSUM detector considers the…

Econometrics · Economics 2022-04-13 Sven Otto , Jörg Breitung

The comparison of different medical treatments from observational studies or across different clinical studies is often biased by confounding factors such as systematic differences in patient demographics or in the inclusion criteria for…

Methodology · Statistics 2025-05-15 Ekkehard Glimm , Lillian Yau

In radiation therapy (RT) treatment planning, multi-criteria optimization (MCO) supports efficient plan selection but is usually solved for population-based dosimetric criteria and ignores patient-specific biological risk, potentially…

Medical Physics · Physics 2026-01-09 Mara Schubert , Katrin Teichert , Zhongxing Liao , Thomas Bortfeld , Ali Ajdari

Reinforcement Learning with Verifiable Rewards (RLVR) has emerged as a promising approach to improve the reasoning abilities of Large Language Models (LLMs). Among RLVR algorithms, Group Relative Policy Optimization (GRPO) and its variants…

Artificial Intelligence · Computer Science 2026-04-21 Zhaokang Liao , Yingguo Gao , Yi Yang , Yongheng Hu , Jingting Ding

This paper proposes an overidentifying restriction test for high-dimensional linear instrumental variable models. The novelty of the proposed test is that it allows the number of covariates and instruments to be larger than the sample size.…

Econometrics · Economics 2024-05-08 Qingliang Fan , Zijian Guo , Ziwei Mei

Over the past decades, various methods for comparing the means of two log-normal have been proposed. Some of them are differing in terms of how the statistic test adjust to accept or to reject the null hypothesis. In this study, a new…

Statistics Theory · Mathematics 2014-05-20 Kamel Abdollahnezhad , M. Babanezhad , Ali Akbar Jafari

Large language models (LLMs) excel on multiple-choice clinical diagnosis benchmarks, yet it is unclear how much of this performance reflects underlying probabilistic reasoning. We study this through questions from MedQA, where the task is…

Computation and Language · Computer Science 2025-12-16 Furong Jia , Yuan Pu , Finn Guo , Monica Agrawal

Mean-based estimators of causal effects in randomized experiments may behave poorly if the potential outcomes have a heavy tail or contain outliers. An alternative estimator proposed by Rosenbaum (1993) estimates a constant additive…

Methodology · Statistics 2026-02-09 Aditya Ghosh , Nabarun Deb , Bikram Karmakar , Bodhisattva Sen