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Diffusion generative models unlock new possibilities for inverse problems as they allow for the incorporation of strong empirical priors in scientific inference. Recently, diffusion models are repurposed for solving inverse problems using…

Diffusion probabilistic models have made their way into a number of high-profile applications since their inception. In particular, there has been a wave of research into using diffusion models in the prediction and design of biomolecular…

Biomolecules · Quantitative Biology 2024-06-05 Trevor Norton , Debswapna Bhattacharya

Blind face restoration methods have shown remarkable performance, particularly when trained on large-scale synthetic datasets with supervised learning. These datasets are often generated by simulating low-quality face images with a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Tianshu Kuai , Sina Honari , Igor Gilitschenski , Alex Levinshtein

Diffusion models recently proved to be remarkable priors for Bayesian inverse problems. However, training these models typically requires access to large amounts of clean data, which could prove difficult in some settings. In this work, we…

Machine Learning · Computer Science 2025-11-04 François Rozet , Gérôme Andry , François Lanusse , Gilles Louppe

This paper addresses the issue of inversion in cases where (1) the observation system is modeled by a linear transformation and additive noise, (2) the problem is ill-posed and regularization is introduced in a Bayesian framework by an a…

Machine Learning · Statistics 2026-02-12 Jean-François Giovannelli

Generative diffusion models can provide powerful prior probability models for inverse problems in imaging, but existing implementations suffer from two key limitations: $(i)$ the prior density is represented implicitly, and $(ii)$ they rely…

Machine Learning · Computer Science 2026-05-19 Nicolas Zilberstein , Santiago Segarra , Eero Simoncelli , Florentin Guth

Diffusion models are a class of generative models that have demonstrated remarkable success in tasks such as image generation. However, one of the bottlenecks of these models is slow sampling due to the delay before the onset of trajectory…

Machine Learning · Statistics 2025-12-25 Li Cunzhi , Louis Kang , Hideaki Shimazaki

Bayesian inference for inverse problems hinges critically on the choice of priors. In the absence of specific prior information, population-level distributions can serve as effective priors for parameters of interest. With the advent of…

Instrumentation and Methods for Astrophysics · Physics 2025-02-11 Gabriel Missael Barco , Alexandre Adam , Connor Stone , Yashar Hezaveh , Laurence Perreault-Levasseur

Electron microscopy (EM) images exhibit anisotropic axial resolution due to the characteristics inherent to the imaging modality, presenting challenges in analysis and downstream tasks.In this paper, we propose a diffusion-model-based…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Kyungryun Lee , Won-Ki Jeong

The remarkable achievements of both generative models of 2D images and neural field representations for 3D scenes present a compelling opportunity to integrate the strengths of both approaches. In this work, we propose a methodology that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Azmi Haider , Dan Rosenbaum

Diffusion models demonstrate remarkable capabilities in capturing complex data distributions and have achieved compelling results in many generative tasks. While they have recently been extended to dense prediction tasks such as depth…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Haorui Ji , Taojun Lin , Hongdong Li

Inverse design problems are common in engineering and materials science. The forward direction, i.e., computing output quantities from design parameters, typically requires running a numerical simulation, such as a FEM, as an intermediate…

Machine Learning · Computer Science 2026-02-18 Jens U. Kreber , Christian Weißenfels , Joerg Stueckler

We present a framework that adapts 2D diffusion models for 3D shape completion from incomplete point clouds. While text-to-image diffusion models have achieved remarkable success with abundant 2D data, 3D diffusion models lag due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yao He , Youngjoong Kwon , Tiange Xiang , Wenxiao Cai , Ehsan Adeli

Note: The final version of this article was published in Computers and Geosciences, Volume 206, January 2026, 106038. DOI: 10.1016/j.cageo.2025.106038. Readers should refer to the published version for the most up-to-date content.…

In this paper, we propose an approach combining diffusion models and inverse problems for the reconstruction of circumstellar disk images. Our method builds upon the Rhapsodie framework for polarimetric imaging, substituting its classical…

Instrumentation and Methods for Astrophysics · Physics 2025-10-17 Quentin Villegas , Laurence Denneulin , Simon Prunet , André Ferrari , Nelly Pustelnik , Éric Thiébaut , Julian Tachella , Maud Langlois

While many unsupervised learning models focus on one family of tasks, either generative or discriminative, we explore the possibility of a unified representation learner: a model which uses a single pre-training stage to address both…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Soumik Mukhopadhyay , Matthew Gwilliam , Vatsal Agarwal , Namitha Padmanabhan , Archana Swaminathan , Srinidhi Hegde , Tianyi Zhou , Abhinav Shrivastava

The Gaussian diffusion model, initially designed for image generation, has recently been adapted for 3D point cloud generation. However, these adaptations have not fully considered the intrinsic geometric characteristics of 3D shapes,…

Graphics · Computer Science 2024-08-01 Dengsheng Chen , Jie Hu , Xiaoming Wei , Enhua Wu

Used as priors for Bayesian inverse problems, diffusion models have recently attracted considerable attention in the literature. Their flexibility and high variance enable them to generate multiple solutions for a given task, such as…

Machine Learning · Computer Science 2025-07-10 Emile Pierret , Bruno Galerne

Recent diffusion-based Single-image 3D portrait generation methods typically employ 2D diffusion models to provide multi-view knowledge, which is then distilled into 3D representations. However, these methods usually struggle to produce…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Haoran Wei , Wencheng Han , Xingping Dong , Jianbing Shen

A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual…

Machine Learning · Computer Science 2025-10-08 Sebastian Wagner-Carena , Aizhan Akhmetzhanova , Sydney Erickson