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We describe a new open-source Python-based package for high accuracy correlated electron calculations using quantum Monte Carlo (QMC) in real space: PyQMC. PyQMC implements modern versions of QMC algorithms in an accessible format, enabling…

In structure-based virtual screening, it is often necessary to evaluate the binding free energy of protein-ligand complexes by considering not only molecular conformations but also how these structures shift and rotate in space. The number…

Quantum Physics · Physics 2025-07-25 Pei-Kun Yang

State-of-the-art language models like T5 have revolutionized the NLP landscape, but their computational demands hinder a large portion of the research community. To address this challenge, we present nanoT5, a specially-optimized PyTorch…

Computation and Language · Computer Science 2023-10-25 Piotr Nawrot

Quantum machine learning (QML) requires significant quantum resources to address practical real-world problems. When the underlying quantum information exhibits hierarchical structures in the data, limitations persist in training complexity…

Quantum Physics · Physics 2026-03-24 Quoc Hoan Tran , Yasuhiro Endo , Hirotaka Oshima

Manipulating quantum computing hardware in the presence of imperfect devices and control systems is a central challenge in realizing useful quantum computers. Susceptibility to noise limits the performance and capabilities of noisy…

I show that a software framework intended primarily for training of neural networks, PyTorch, is easily applied to a general function minimisation problem in science. The qualities of PyTorch of ease-of-use and very high efficiency are…

Instrumentation and Methods for Astrophysics · Physics 2018-11-20 Bojan Nikolic

Given the impending timeline of developing good-quality quantum processing units, it is time to rethink the approach to advance quantum computing research. Rather than waiting for quantum hardware technologies to mature, we need to start…

Quantum Physics · Physics 2024-05-12 Koen Bertels , Emma Turki , Tamara Sarac , Aritra Sarkar , Imran Ashraf

Over the last few decades, quantum chemistry has progressed through the development of computational methods based on modern digital computers. However, these methods can hardly fulfill the exponentially-growing resource requirements when…

Quantum Physics · Physics 2014-01-08 M. -H. Yung , J. Casanova , A. Mezzacapo , J. McClean , L. Lamata , A. Aspuru-Guzik , E. Solano

Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbitrary PyTorch models…

Scientific progress is tightly coupled to the emergence of new research tools. Today, machine learning (ML)-especially deep learning (DL)-has become a transformative instrument for quantum science and technology. Owing to the intrinsic…

Quantum Physics · Physics 2025-08-15 Timothy Heightman , Marcin Płodzień

Manipulate and control of the complex quantum system with high precision are essential for achieving universal fault tolerant quantum computing. For a physical system with restricted control resources, it is a challenge to control the…

Quantum Physics · Physics 2021-01-20 Zheng An , Qi-Kai He , Hai-Jing Song , D. L. Zhou

The synthesis of high-performance computing (particularly graphics processing units), cloud computing services (like Google Colab), and high-level deep learning frameworks (such as PyTorch) has powered the burgeoning field of artificial…

Computational Physics · Physics 2020-03-23 Vaibhav Vavilala

We present QuantumToolbox$.$jl, an open-source Julia package for simulating open quantum systems. Designed with a syntax familiar to users of QuTiP (Quantum Toolbox in Python), it harnesses Julia's high-performance ecosystem to deliver fast…

Quantum Physics · Physics 2025-10-06 Alberto Mercurio , Yi-Te Huang , Li-Xun Cai , Yueh-Nan Chen , Vincenzo Savona , Franco Nori

We introduce ProjectQ, an open source software effort for quantum computing. The first release features a compiler framework capable of targeting various types of hardware, a high-performance simulator with emulation capabilities, and…

Quantum Physics · Physics 2018-02-01 Damian S. Steiger , Thomas Häner , Matthias Troyer

The training, testing, and deployment, of autonomous vehicles requires realistic and efficient simulators. Moreover, because of the high variability between different problems presented in different autonomous systems, these simulators need…

The PySCF package has emerged as a powerful and flexible open-source platform for quantum chemistry simulations. However, the efficiency of electronic structure calculations can vary significantly depending on the choice of computational…

Chemical Physics · Physics 2025-06-10 Zhichen Pu , Qiming Sun

We present TensorCircuit-NG, a next-generation quantum software platform designed to bridge the gap between quantum physics, artificial intelligence, and high-performance computing. Moving beyond the scope of traditional circuit simulators,…

Local execution of AI on edge devices is important for low latency and offline operation. However, deploying models on diverse hardware remains fragmented, often requiring model conversion or complete reimplementation outside the PyTorch…

Quantum machine learning is a rapidly growing field at the intersection of quantum technology and artificial intelligence. This review provides a two-fold overview of several key approaches that can offer advancements in both the…

Quantum Physics · Physics 2023-03-07 Alexey Melnikov , Mohammad Kordzanganeh , Alexander Alodjants , Ray-Kuang Lee

PyTorch \texttt{2.x} introduces a compiler designed to accelerate deep learning programs. However, for machine learning researchers, adapting to the PyTorch compiler to full potential can be challenging. The compiler operates at the Python…

Machine Learning · Computer Science 2024-03-22 Kaichao You , Runsheng Bai , Meng Cao , Jianmin Wang , Ion Stoica , Mingsheng Long