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Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Image data augmentation constitutes a critical methodology in modern computer vision tasks, since it can facilitate towards enhancing the diversity and quality of training datasets; thereby, improving the performance and robustness of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Panagiotis Alimisis , Ioannis Mademlis , Panagiotis Radoglou-Grammatikis , Panagiotis Sarigiannidis , Georgios Th. Papadopoulos

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Multiple Instance Learning (MIL) is a popular weakly-supervised method for various applications, with a particular interest in histological whole slide image (WSI) classification. Due to the gigapixel resolution of WSI, applications of MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Zhangsihao Yang , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Joint Embedding Architecture-based self-supervised learning methods have attributed the composition of data augmentations as a crucial factor for their strong representation learning capabilities. While regional dropout strategies have…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Arjon Das , Xin Zhong

Deep learning has been widely applied in neuroimaging, including predicting brain-phenotype relationships from magnetic resonance imaging (MRI) volumes. MRI data usually requires extensive preprocessing prior to modeling, but variation…

Machine Learning · Computer Science 2023-10-17 Xinhui Li , Alex Fedorov , Mrinal Mathur , Anees Abrol , Gregory Kiar , Sergey Plis , Vince Calhoun

Few-shot class incremental learning implies the model to learn new classes while retaining knowledge of previously learned classes with a small number of training instances. Existing frameworks typically freeze the parameters of the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Parinita Nema , Vinod K Kurmi

Convolutional neural networks for visual recognition require large amounts of training samples and usually benefit from data augmentation. This paper proposes PatchMix, a data augmentation method that creates new samples by composing…

Computer Vision and Pattern Recognition · Computer Science 2022-04-04 Paola Cascante-Bonilla , Arshdeep Sekhon , Yanjun Qi , Vicente Ordonez

Physics-guided deep learning (PG-DL) via algorithm unrolling has received significant interest for improved image reconstruction, including MRI applications. These methods unroll an iterative optimization algorithm into a series of…

Image and Video Processing · Electrical Eng. & Systems 2021-05-17 Burhaneddin Yaman , Seyed Amir Hossein Hosseini , Steen Moeller , Mehmet Akçakaya

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Whole Slide Image (WSI) classification relies on Multiple Instance Learning (MIL) with spatial patch features, yet existing methods struggle to capture global dependencies due to the immense size of WSIs and the local nature of patch…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anthony Bilic , Guangyu Sun , Ming Li , Md Sanzid Bin Hossain , Yu Tian , Wei Zhang , Laura Brattain , Dexter Hadley , Chen Chen

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

As data requirements continue to grow, efficient learning increasingly depends on the curation and distillation of high-value data rather than brute-force scaling of model sizes. In the case of a hyperspectral image (HSI), the challenge is…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Abhiroop Chatterjee , Susmita Ghosh

Data augmentations are widely used in training medical image deep learning models to increase the diversity and size of sparse datasets. However, commonly used augmentation techniques can result in loss of clinically relevant information…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Adrit Rao , Andrea Fisher , Ken Chang , John Christopher Panagides , Katherine McNamara , Joon-Young Lee , Oliver Aalami

Convolutional Neural Network (CNN) models have become the state-of-the-art for most computer vision tasks with natural images. However, these are not best suited for multi-gigapixel resolution Whole Slide Images (WSIs) of histology slides…

Computer Vision and Pattern Recognition · Computer Science 2017-07-28 Abhinav Agarwalla , Muhammad Shaban , Nasir M. Rajpoot