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Large Language Models (LLMs) hold significant promise for electrocardiogram (ECG) analysis, yet challenges remain regarding transferability, time-scale information learning, and interpretability. Current methods suffer from model-specific…

Artificial Intelligence · Computer Science 2025-09-17 Yong Xia , Jingxuan Li , YeTeng Sun , Jiarui Bu

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

Electrocardiogram (ECG) analysis is crucial for diagnosing heart disease, but most self-supervised learning methods treat ECG as a generic time series, overlooking physiologic semantics and rhythm-level structure. Existing contrastive…

Machine Learning · Computer Science 2026-02-27 Xin Wang , Burcu Ozek , Aruna Mohan , Amirhossein Ravari , Or Zilbershot , Fatemeh Afghah

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

A language is made up of an infinite/finite number of sentences, which in turn is composed of a number of words. The Electrocardiogram (ECG) is the most popular noninvasive medical tool for studying heart function and diagnosing various…

Signal Processing · Electrical Eng. & Systems 2024-07-17 Prapti Ganguly , Wazib Ansar , Amlan Chakrabarti

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Text generating capabilities have undergone a substantial transformation with the introduction of large language models (LLMs). Electroencephalography (EEG)-based text production is still difficult, though, because it requires a lot of data…

Human-Computer Interaction · Computer Science 2025-11-18 Khushiyant

Electrocardiogram (ECG) is essential for the clinical diagnosis of arrhythmias and other heart diseases, but deep learning methods based on ECG often face limitations due to the need for high-quality annotations. Although previous ECG…

Machine Learning · Computer Science 2025-02-18 Jiarui Jin , Haoyu Wang , Hongyan Li , Jun Li , Jiahui Pan , Shenda Hong

Decoding linguistic information from non-invasive brain signals using EEG has gained increasing research attention due to its vast applicational potential. Recently, a number of works have adopted a generative-based framework to decode…

Computation and Language · Computer Science 2024-08-12 Jinzhao Zhou , Yiqun Duan , Ziyi Zhao , Yu-Cheng Chang , Yu-Kai Wang , Thomas Do , Chin-Teng Lin

Large language models (LLMs) have achieved remarkable success across various natural language processing tasks. However, most LLM models use traditional tokenizers like BPE and SentencePiece, which fail to capture the finer nuances of a…

Computation and Language · Computer Science 2025-05-26 Pramit Bhattacharyya , Arnab Bhattacharya

The prevalent use of Byte Pair Encoding (BPE) in Large Language Models (LLMs) facilitates robust handling of subword units and avoids issues of out-of-vocabulary words. Despite its success, a critical challenge persists: long tokens, rich…

Computation and Language · Computer Science 2024-11-11 Haoran Lian , Yizhe Xiong , Zijia Lin , Jianwei Niu , Shasha Mo , Hui Chen , Peng Liu , Guiguang Ding

A language is constructed of a finite/infinite set of sentences composing of words. Similar to natural languages, Electrocardiogram (ECG) signal, the most common noninvasive tool to study the functionality of the heart and diagnose several…

Signal Processing · Electrical Eng. & Systems 2020-06-17 Sajad Mousavi , Fatemeh Afghah , Fatemeh Khadem , U. Rajendra Acharya

Electrocardiogram (ECG) synthesis is the area of research focused on generating realistic synthetic ECG signals for medical use without concerns over annotation costs or clinical data privacy restrictions. Traditional ECG generation models…

Computation and Language · Computer Science 2023-03-17 Hyunseung Chung , Jiho Kim , Joon-myoung Kwon , Ki-Hyun Jeon , Min Sung Lee , Edward Choi

Subword tokenization methods, such as Byte-Pair Encoding (BPE), significantly impact the performance and efficiency of large language models (LLMs). The standard approach involves training a general-purpose tokenizer that uniformly…

Computation and Language · Computer Science 2026-01-30 Vijini Liyanage , François Yvon

Automating analog circuit design remains a longstanding challenge in Electronic Design Automation (EDA). While Transformer-based Large Language Models (LLMs) have revolutionized software code generation, their application to analog hardware…

Artificial Intelligence · Computer Science 2026-05-08 Md Touhidul Islam , Sujan Kumar Saha , Farimah Farahmandi , Mark Tehranipoor

Tokenization is associated with many poorly understood shortcomings in language models (LMs), yet remains an important component for long sequence scaling purposes. This work studies how tokenization impacts model performance by analyzing…

Computation and Language · Computer Science 2025-04-15 Buu Phan , Brandon Amos , Itai Gat , Marton Havasi , Matthew Muckley , Karen Ullrich

Tokenization is a foundational step in natural language processing (NLP) tasks, bridging raw text and language models. Existing tokenization approaches like Byte-Pair Encoding (BPE) originate from the field of data compression, and it has…

Computation and Language · Computer Science 2024-10-08 Craig W. Schmidt , Varshini Reddy , Haoran Zhang , Alec Alameddine , Omri Uzan , Yuval Pinter , Chris Tanner

The success of pretrained transformer language models (LMs) in natural language processing has led to a wide range of pretraining setups. In particular, these models employ a variety of subword tokenization methods, most notably byte-pair…

Computation and Language · Computer Science 2020-10-06 Kaj Bostrom , Greg Durrett

The advent of multimodal large language models (MLLMs) has sparked interest in their application to electrocardiogram (ECG) analysis. However, existing ECG-focused MLLMs primarily focus on report generation tasks, often limited to single…

Computation and Language · Computer Science 2025-11-13 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

Bytes form the basis of the digital world and thus are a promising building block for multimodal foundation models. Recently, Byte Language Models (BLMs) have emerged to overcome tokenization, yet the excessive length of bytestreams…

Computation and Language · Computer Science 2025-02-21 Eric Egli , Matteo Manica , Jannis Born
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