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Parameter estimation and associated uncertainty quantification is an important problem in dynamical systems characterized by ordinary differential equation (ODE) models that are often nonlinear. Typically, such models have analytically…

Computation · Statistics 2024-03-26 Wai Meng Kwok , Sarat Chandra Dass , George Streftaris

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

Applications · Statistics 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Accurate real-time monitoring systems of influenza outbreaks help public health officials make informed decisions that may help save lives. We show that information extracted from cloud-based electronic health records databases, in…

This study presents a family of stochastic models for the dynamics of influenza in a closed human population. We consider treatment for the disease in the form of vaccination, and incorporate the periods of effectiveness of the vaccine and…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

Background: Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty.…

Influenza is a contagious respiratory illness that causes significant human morbidity and mortality, affecting 5-15% of the population in a typical epidemic season. Human influenza epidemics are caused by types A and B, with roughly 25% of…

Populations and Evolution · Quantitative Biology 2016-10-14 Yidan Pan , Michael W. Deem

We develop various AI models to predict hospitalization on a large (over 110$k$) cohort of COVID-19 positive-tested US patients, sourced from March 2020 to February 2021. Models range from Random Forest to Neural Network (NN) and Time…

On 11 June the World Health Organization officially raised the phase of pandemic alert (with regard to the new H1N1 influenza strain) to level 6. We use a global structured metapopulation model integrating mobility and transportation data…

As the COVID-19 spread over the globe and new variants of COVID-19 keep occurring, reliable real-time forecasts of COVID-19 hospitalizations are critical for public health decision on medical resources allocations such as ICU beds,…

Machine Learning · Computer Science 2022-02-09 Tao Wang , Simin Ma , Soobin Baek , Shihao Yang

The impact of climate conditions on influenza epidemiology has mostly been studied by addressing a singular aspect of transmission and a climate variable correlating to it. As climate change unfolds at an unprecedented rate, we urgently…

Quantitative Methods · Quantitative Biology 2025-01-24 Branislava Lalic , Vladimir Koci , Ana Firanj Sremac , Zorana Jovanovic Andersen

Accurate epidemic forecasting is critical for effective public health interventions. This study compares Bayesian and Frequentist estimation frameworks within deterministic compartmental epidemic models, focusing on nonlinear least squares…

Quantitative Methods · Quantitative Biology 2025-09-09 Hamed Karami , Ruiyan Luo , Pejman Sanaei , Gerardo Chowell

This document is part of a series of near real-time weekly influenza forecasts made during the 2012-2013 influenza season. Here we present results of a forecast initiated following assimilation of observations for Week 51 (i.e. the forecast…

Populations and Evolution · Quantitative Biology 2013-01-01 Jeffrey Shaman , Alicia Karspeck , Marc Lipsitch

This study focuses on the modeling, mathematical analysis, developing theories, and numerical simulation of Influenza virus transmission. We have proved the existence, uniqueness, positivity, and boundedness of the solutions. Also,…

Populations and Evolution · Quantitative Biology 2024-03-19 Kazi Mehedi Mohammad , Asma Akter Akhi , Md. Kamrujjaman

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

Hospitalizations that follow closely on the heels of one or more emergency department visits are often symptoms of missed opportunities to form a proper diagnosis. These diagnostic errors imply a failure to recognize the need for…

Machine Learning · Computer Science 2024-07-02 Dat Hong , Philip M. Polgreen , Alberto Maria Segre

In this work, we aim to determine the main factors driving behavioral change during the seasonal flu. To this end, we analyze a unique dataset comprised of 599 surveys completed by 434 Italian users of Influweb, a Web platform for…

Physics and Society · Physics 2020-07-01 Nicolò Gozzi , Daniela Perrotta , Daniela Paolotti , Nicola Perra

Early detection and modeling of a contagious epidemic can provide important guidance about quelling the contagion, controlling its spread, or the effective design of countermeasures. A topic of recent interest has been to design social…

Social and Information Networks · Computer Science 2016-03-09 Huijuan Shao , K. S. M. Tozammel Hossain , Hao Wu , Maleq Khan , Anil Vullikanti , B. Aditya Prakash , Madhav Marathe , Naren Ramakrishnan

Measles presents a unique and imminent challenge for epidemiologists and public health officials: the disease is highly contagious, yet vaccination rates are declining precipitously in many localities. Consequently, the risk of a measles…

Applications · Statistics 2019-07-02 Daniel R. Kowal

Pandemics have the potential to cause immense disruption and damage to communities and societies. In this paper, we model the Influenza Pandemic of 2009. We propose a hybrid model to determine how the pandemic spreads through the world. The…

Populations and Evolution · Quantitative Biology 2010-06-02 Teruhiko Yoneyama , Mukkai S. Krishnamoorthy

Surveillance data serving for epidemic alert systems are typically fully aggregated in space. However, epidemics may be spatially heterogeneous, undergoing distinct dynamics in distinct regions of the surveillance area. We unveil this in…

Populations and Evolution · Quantitative Biology 2018-03-30 Pavel Polyakov , Cécile Souty , Pierre-Yves Böelle , Romulus Breban
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