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Synthetic Biology is the new engineering-based approach to biology that includes applications of designing complex biological devices. At present, it is not yet clear what will emerge as the defining principles of Synthetic Biology. One…

Quantitative Methods · Quantitative Biology 2011-03-30 A. X. C. N. Valente , Stephen S. Fong

The development of artificial intelligence (AI) and robotics are both based on the tenet of "science and technology are people-oriented", and both need to achieve efficient communication with the human brain. Based on multi-disciplinary…

Neurons and Cognition · Quantitative Biology 2024-06-27 Shengjie Zheng , Ling Liu , Junjie Yang , Jianwei Zhang , Tao Su , Bin Yue , Xiaojian Li

The human brain has immense learning capabilities at extreme energy efficiencies and scale that no artificial system has been able to match. For decades, reverse engineering the brain has been one of the top priorities of science and…

At present, artificial intelligence in the form of machine learning is making impressive progress, especially the field of deep learning (DL) [1]. Deep learning algorithms have been inspired from the beginning by nature, specifically by the…

Artificial Intelligence · Computer Science 2020-04-07 Gordana Dodig-Crnkovic

The independent evolution of intelligence in biological and artificial systems offers a unique opportunity to identify its fundamental computational principles. Here we show that large language models spontaneously develop synergistic cores…

Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this…

Neurons and Cognition · Quantitative Biology 2018-11-01 David G. T. Barrett , Ari S. Morcos , Jakob H. Macke

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

Machine Learning · Computer Science 2025-04-07 Yingzhou Lu , Lulu Chen , Yuanyuan Zhang , Minjie Shen , Huazheng Wang , Xiao Wang , Capucine van Rechem , Tianfan Fu , Wenqi Wei

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

The convergence of artificial intelligence (AI) and synthetic biology is rapidly accelerating the pace of biological discovery and engineering. AI techniques, such as large language models and biological design tools, are enabling the…

Other Quantitative Biology · Quantitative Biology 2024-05-01 Cindy Vindman , Benjamin Trump , Christopher Cummings , Madison Smith , Alexander J. Titus , Ken Oye , Valentina Prado , Eyup Turmus , Igor Linkov

Deep learning has achieved transformative performance across diverse domains, largely driven by large-scale and high-quality training data. In contrast, the development of brain-computer interfaces (BCIs) is fundamentally constrained by…

Machine Learning · Computer Science 2026-05-20 Ziwei Wang , Zhentao He , Xingyi He , Hongbin Wang , Tianwang Jia , Jingwei Luo , Siyang Li , Xiaoqing Chen , Dongrui Wu

Computational intelligence is broadly defined as biologically-inspired computing. Usually, inspiration is drawn from neural systems. This article shows how to analyze neural systems using information theory to obtain constraints that help…

Neurons and Cognition · Quantitative Biology 2018-05-11 Michael Wibral , Joseph T. Lizier , Viola Priesemann

The potential of synthetic biology techniques for designing complex cellular circuits able to solve complicated computations opens a whole domain of exploration, beyond experiments and theory. Such cellular circuits could be used to carry…

Neurons and Cognition · Quantitative Biology 2013-10-21 Luís F. Seoane , Ricard V. Solé

The underlying physiological mechanisms of generating conscious states are still unknown. To make progress on the problem of consciousness, we will need to experimentally design a system that evolves in a similar way our brains do. Recent…

Emerging Technologies · Computer Science 2014-11-20 Dorian Aur

Catastrophic forgetting has been the leading issue in the domain of lifelong learning in artificial systems. Current artificial systems are reasonably good at learning domains they have seen before; however, as soon as they encounter…

Machine Learning · Computer Science 2024-12-02 Ram Zaveri

Biological intelligence is inherently adaptive -- animals continually adjust their actions based on environmental feedback. However, creating adaptive artificial intelligence (AI) remains a major challenge. The next frontier is to go beyond…

Neurons and Cognition · Quantitative Biology 2026-01-06 Mackenzie Weygandt Mathis

Biomedical research centers can empower basic discovery and novel therapeutic strategies by leveraging their large-scale datasets from experiments and patients. This data, together with new technologies to create and analyze it, has ushered…

In nature, biological organisms jointly evolve both their morphology and their neurological capabilities to improve their chances for survival. Consequently, task information is encoded in both their brains and their bodies. In robotics,…

Robotics · Computer Science 2020-06-15 Ana Pervan , Todd D. Murphey

In recent years, several studies have provided insight on the functioning of the brain which consists of neurons and form networks via interconnection among them by synapses. Neural networks are formed by interconnected systems of neurons,…

Neurons and Cognition · Quantitative Biology 2021-01-22 Martin C. Nwadiugwu

Biology has changed radically in the last two decades, transitioning from a descriptive science into a design science. Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or…

Quantitative Methods · Quantitative Biology 2021-01-27 Tijana Radivojević , Zak Costello , Kenneth Workman , Hector Garcia Martin

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo