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A notion of biologic system or just a system implies a functional wholeness of comprising system components. Positive and negative feedback are the examples of how the idea to unite anatomical elements in the whole functional structure was…

Other Quantitative Biology · Quantitative Biology 2014-06-03 Garri Davydyan

Lots of bio-inspired research works have been conducted in self-adaptive software. They have focused on the external behavior of biological entities without their genetic material that causes this behavior and constitutes the challenge this…

Software Engineering · Computer Science 2019-04-30 Enas Nafar , Said Ghoul

Many features of physical systems, both qualitative and quantitative, become sharply defined or tractable only in some limiting situation. Examples are phase transitions in the thermodynamic limit, the emergence of classical mechanics from…

Mathematical Physics · Physics 2024-02-16 Lauritz van Luijk , Alexander Stottmeister , Reinhard F. Werner

Soft robotics has opened a unique path to flexibility and environmental adaptability, learning from nature and reproducing biological behaviors. Nature implies answers for how to apply robots to real life. To find out how we learn from…

Robotics · Computer Science 2023-02-27 Yang Yang , Zhiguo He , Pengcheng Jiao , Hongliang Ren

Biological systems exhibit two structural features on many levels of organization: sparseness, in which only a small fraction of possible interactions between components actually occur; and modularity - the near decomposability of the…

Molecular Networks · Quantitative Biology 2013-12-25 Tamar Friedlander , Avraham E. Mayo , Tsvi Tlusty , Uri Alon

Many segmentation tasks, such as medical image segmentation or future state prediction, are inherently ambiguous, meaning that multiple predictions are equally correct. Current methods typically rely on generative models to capture this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Sebastian Gerard , Josephine Sullivan

Soft robots are typically approximated as low-dimensional systems, especially when learning-based methods are used. This leads to models that are limited in their capability to predict the large number of deformation modes and interactions…

Robotics · Computer Science 2022-05-10 Thomas George Thuruthel , Fumiya Iida

Biological systems are characterized by the ubiquitous roles of weak, that is, non-covalent molecular interactions, small, often very small, numbers of specific molecules per cell, and Brownian motion. These combine to produce stochastic…

Cell Behavior · Quantitative Biology 2023-04-27 Michael W. Klymkowsky

Noise is a ubiquitous feature of the physical world. As a result, the first prerequisite of life is fault tolerance: maintaining integrity of state despite external bombardment. Recent experimental advances have revealed that biological…

Populations and Evolution · Quantitative Biology 2023-04-14 Trevor McCourt , Ila R. Fiete , Isaac L. Chuang

A central feature of complex systems is the relevance and entanglement of different levels of description. For instance, the dynamics of ecosystems can be alternatively described in terms of large ecological processes and classes of…

Populations and Evolution · Quantitative Biology 2025-10-06 Juan Giral Martínez , Silvia de Monte , Matthieu Barbier

Biological soft tissues exhibit substantial inter-subject variability, making the automation of constitutive material modeling essential for patient-specific analysis and design. Such materials are not only highly nonlinear but also display…

Computational Physics · Physics 2026-04-16 Bahador Bahmani

At low temperatures ultrasoft particle systems develop interesting phases via the self-assembly of particle clusters. In this study we develop a general zero-temperature analysis fully characterizing the ground state of such models in two…

Soft Condensed Matter · Physics 2025-02-25 Matheus de Mello , Rogelio Díaz-Méndez , Alejandro Mendoza-Coto

With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

Molecular Networks · Quantitative Biology 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

Macroscopic dynamical descriptions of complex physical systems are crucial for understanding and controlling material behavior. With the growing availability of data and compute, machine learning has become a promising alternative to…

Computational Physics · Physics 2026-03-24 Mengyi Chen , Pengru Huang , Kostya S. Novoselov , Qianxiao Li

Natural systems are remarkably robust and resilient, maintaining essential functions despite variability, uncertainty, and hostile conditions. Understanding these nonlinear, dynamic behaviours is challenging because such systems involve…

Mathematical Physics · Physics 2025-12-02 Daniele Proverbio , Rami Katz , Giulia Giordano

Despite their widespread utility across domains, basic network models face fundamental limitations when applied to complex biological systems, particularly in neuroscience. This paper critically examines these limitations and explores…

Other Quantitative Biology · Quantitative Biology 2024-11-07 Luiz Pessoa

Biological phenotypes are products of complex evolutionary processes in which selective forces influence multiple biological trait measurements in unknown ways. Phylogenetic factor analysis disentangles these relationships across the…

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Building on the recently derived inhomogeneous mode-coupling theory, we extend the generalised mode-coupling theory of supercooled liquids to inhomogeneous environments. This provides a first-principles-based, systematic and rigorous way of…

Statistical Mechanics · Physics 2023-01-11 Corentin C. L. Laudicina , Chengjie Luo , Kunimasa Miyazaki , Liesbeth M. C. Janssen

Structure, composition and stability of ecological populations are shaped by the inter- and intra-species interactions within these communities. It remains to be fully understood how the interplay of these interactions with other factors,…

Populations and Evolution · Quantitative Biology 2023-01-16 Nava Leibovich , Jeremy Rothschild , Sidhartha Goyal , Anton Zilman
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