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Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would…

Machine Learning · Computer Science 2022-10-07 Flemming Kondrup , Thomas Jiralerspong , Elaine Lau , Nathan de Lara , Jacob Shkrob , My Duc Tran , Doina Precup , Sumana Basu

The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units. Both prolonged dependence on mechanical…

Artificial Intelligence · Computer Science 2017-04-24 Niranjani Prasad , Li-Fang Cheng , Corey Chivers , Michael Draugelis , Barbara E Engelhardt

Mechanical ventilation (MV) is a life-saving intervention for patients with acute respiratory failure (ARF) in the ICU. However, inappropriate ventilator settings could cause ventilator-induced lung injury (VILI). Also, clinicians workload…

Machine Learning · Computer Science 2026-03-13 Hang Yu , Huidong Liu , Qingchen Zhang , William Joy , Kateryna Nikulina , Andreas A. Schuppert , Sina Saffaran , Declan Bates

In this paper, we adopt conformal prediction, a distribution-free uncertainty quantification (UQ) framework, to obtain confidence prediction intervals with coverage guarantees for Deep Operator Network (DeepONet) regression. Initially, we…

Machine Learning · Computer Science 2024-02-26 Christian Moya , Amirhossein Mollaali , Zecheng Zhang , Lu Lu , Guang Lin

In the intensive care unit, the capability to predict the need for mechanical ventilation (MV) facilitates more timely interventions to improve patient outcomes. Recent works have demonstrated good performance in this task utilizing machine…

Machine Learning · Computer Science 2024-07-24 Anwesh Mohanty , Supreeth P. Shashikumar , Jonathan Y. Lam , Shamim Nemati

The issue of failed weaning is a critical concern in the intensive care unit (ICU) setting. This scenario occurs when a patient experiences difficulty maintaining spontaneous breathing and ensuring a patent airway within the first 48 hours…

Machine Learning · Computer Science 2025-03-05 Hernando Gonzalez , Carlos Julio Arizmendi , Beatriz F. Giraldo

Machine learning methods are increasingly widely used in high-risk settings such as healthcare, transportation, and finance. In these settings, it is important that a model produces calibrated uncertainty to reflect its own confidence and…

Artificial Intelligence · Computer Science 2022-09-09 Sophia Sun

Uncertainty quantification (UQ) is the process of systematically determining and characterizing the degree of confidence in computational model predictions. In the context of systems biology, especially with dynamic models, UQ is crucial…

Machine Learning · Statistics 2024-10-29 Alberto Portela , Julio R. Banga , Marcos Matabuena

Robust uncertainty quantification (UQ) remains a critical barrier to the safe deployment of deep learning in real-time virtual sensing, particularly in high-stakes domains where sparse, noisy, or non-collocated sensor data are the norm. We…

Machine Learning · Computer Science 2025-07-17 Kazuma Kobayashi , Shailesh Garg , Farid Ahmed , Souvik Chakraborty , Syed Bahauddin Alam

Mechanical ventilation is one of the most widely used therapies in the ICU. However, despite broad application from anaesthesia to COVID-related life support, many injurious challenges remain. We frame these as a control problem:…

Clinical decision support systems (CDSS) will play an in-creasing role in improving the quality of medical care for critically ill patients. However, due to limitations in current informatics infrastructure, CDSS do not always have…

Machine Learning · Computer Science 2019-05-01 Gregory B. Rehm , Brooks T. Kuhn , Jimmy Nguyen , Nicholas R. Anderson , Chen-Nee Chuah , Jason Y. Adams

Mechanical ventilation is a critical life support intervention that delivers controlled air and oxygen to a patient's lungs, assisting or replacing spontaneous breathing. While several data-driven approaches have been proposed to optimize…

Machine Learning · Computer Science 2025-01-10 Joo Seung Lee , Malini Mahendra , Anil Aswani

Deep learning has been shown to be highly effective for automatic modulation classification (AMC), which is a pivotal technology for next-generation cognitive communications. Yet, existing deep learning methods for AMC often lack robust…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Huian Yang , Rajeev Sahay

Purpose: To develop a robust deep learning framework for non-contrast-enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological non-stationarity. Methods: We introduce VQ-Wave…

Medical Physics · Physics 2026-05-05 Grzegorz Bauman , Pavlos Panos , Philipp Latzin , Oliver Bieri

Heating, Ventilation, and Air Conditioning (HVAC) is a major electricity end-use with a substantial potential for providing grid services, such as demand response. Harnessing this flexibility requires accurate modeling of the thermal…

Systems and Control · Electrical Eng. & Systems 2025-12-02 Pietro Favaro , Jean-François Toubeau , François Vallée , Yury Dvorkin

Reliable uncertainty quantification is crucial for reinforcement learning (RL) in high-stakes settings. We propose a unified conformal prediction framework for infinite-horizon policy evaluation that constructs distribution-free prediction…

Machine Learning · Statistics 2025-10-31 Feichen Gan , Youcun Lu , Yingying Zhang , Yukun Liu

While deep learning offers tremendous promise for scientific and medical imaging, any failures and hallucinations (predictions that do not coincide with reality) are hard to pinpoint and can have serious downstream consequences. Uncertainty…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Cassandra Tong Ye , Shamus Li , Tyler King , Kristina Monakhova

Meshing is a critical, but user-intensive process necessary for stable and accurate simulations in computational fluid dynamics (CFD). Mesh generation is often a bottleneck in CFD pipelines. Adaptive meshing techniques allow the mesh to be…

Machine Learning · Computer Science 2022-12-06 Cooper Lorsung , Amir Barati Farimani

On top of machine learning models, uncertainty quantification (UQ) functions as an essential layer of safety assurance that could lead to more principled decision making by enabling sound risk assessment and management. The safety and…

Machine Learning · Computer Science 2024-03-28 Venkat Nemani , Luca Biggio , Xun Huan , Zhen Hu , Olga Fink , Anh Tran , Yan Wang , Xiaoge Zhang , Chao Hu

We present a novel statistical approach to incorporating uncertainty awareness in model-free distributional reinforcement learning involving quantile regression-based deep Q networks. The proposed algorithm, $\textit{Calibrated Evidential…

Machine Learning · Computer Science 2024-06-05 Alex Christopher Stutts , Danilo Erricolo , Theja Tulabandhula , Amit Ranjan Trivedi
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