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Longitudinal studies with binary or ordinal responses are widely encountered in various disciplines, where the primary focus is on the temporal evolution of the probability of each response category. Traditional approaches build from the…

Methodology · Statistics 2024-09-04 Jizhou Kang , Athanasios Kottas

The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

Machine Learning · Statistics 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

We propose efficient computational methods to fit multivariate Gaussian additive models, where the mean vector and the covariance matrix are allowed to vary with covariates, in an empirical Bayes framework. To guarantee the…

Computation · Statistics 2025-04-07 Vincenzo Gioia , Matteo Fasiolo , Ruggero Bellio , Simon N. Wood

In various applications with large spatial regions, the relationship between the response variable and the covariates is expected to exhibit complex spatial patterns. We propose a spatially clustered varying coefficient model, where the…

Methodology · Statistics 2020-07-21 Fangzheng Lin , Yanlin Tang , Huichen Zhu , Zhongyi Zhu

We consider the inference problem for high-dimensional linear models, when covariates have an underlying spatial organization reflected in their correlation. A typical example of such a setting is high-resolution imaging, in which…

Methodology · Statistics 2021-06-07 Jérôme-Alexis Chevalier , Tuan-Binh Nguyen , Bertrand Thirion , Joseph Salmon

Given $n$ i.i.d. observations of a random vector $(X,Z)$, where $X$ is a high-dimensional vector and $Z$ is a low-dimensional index variable, we study the problem of estimating the conditional inverse covariance matrix $\Omega(z) =…

Machine Learning · Statistics 2014-12-25 Jialei Wang , Mladen Kolar

Statistical modelling of covariate distributions allows to generate virtual populations or to impute missing values in a covariate dataset. Covariate distributions typically have non-Gaussian margins and show nonlinear correlation…

Applications · Statistics 2025-03-20 Niklas Hartung , Aleksandra Khatova

This work develops a multivariate extension of the Fixed Rank Kriging (FRK) framework for spatial prediction in settings where multiple spatial processes may provide complementary information. The goal is to preserve the computational…

Methodology · Statistics 2026-03-24 Gaia Caringi , Piercesare Secchi

Machine learning can benefit from causal discovery for interpretation and from causal inference for generalization. In this line of research, a few invariant learning algorithms for out-of-distribution (OOD) generalization have been…

Machine Learning · Computer Science 2023-04-06 Borja Guerrero Santillan

Standard models assign disease progression to discrete categories or stages based on well-characterized clinical markers. However, such a system is potentially at odds with our understanding of the underlying biology, which in highly…

Machine Learning · Statistics 2017-01-11 Kieran R. Campbell , Christopher Yau

Key challenges in the analysis of highly multivariate large-scale spatial stochastic processes, where both the number of components (p) and spatial locations (n) can be large, include achieving maximal sparsity in the joint precision…

Methodology · Statistics 2026-01-27 Xiaoqing Chen , Peter Diggle , James V. Zidek , Gavin Shaddick

Multi-view data provides complementary information on the same set of observations, with multi-omics and multimodal sensor data being common examples. Analyzing such data typically requires distinguishing between shared (joint) and unique…

Machine Learning · Statistics 2025-08-14 Renat Sergazinov , Armeen Taeb , Irina Gaynanova

In this paper, we focus on the variable selection techniques for a class of semiparametric spatial regression models which allow one to study the effects of explanatory variables in the presence of the spatial information. The spatial…

Methodology · Statistics 2021-06-03 Guannan Wang , Jue Wang

Spatio-temporal prediction of levels of an environmental exposure is an important problem in environmental epidemiology. Our work is motivated by multiple studies on the spatio-temporal distribution of mobile source, or traffic related,…

Applications · Statistics 2014-11-14 Nikolay Bliznyuk , Christopher J. Paciorek , Joel Schwartz , Brent Coull

The modeling of high-dimensional spatio-temporal processes presents a fundamental dichotomy between the probabilistic rigor of classical geostatistics and the flexible, high-capacity representations of deep learning. While Gaussian…

Machine Learning · Computer Science 2025-12-22 Yuri Calleo

This paper proposes a new robust smooth-threshold estimating equation to select important variables and automatically estimate parameters for high dimensional longitudinal data. A novel working correlation matrix is proposed to capture…

Methodology · Statistics 2021-11-30 Liya Fu , Jiaqi Li , You-Gan Wang

In this paper, we propose a novel variable selection approach in the framework of multivariate linear models taking into account the dependence that may exist between the responses. It consists in estimating beforehand the covariance matrix…

Statistics Theory · Mathematics 2017-07-14 Marie Perrot-Dockès , Céline Lévy-Leduc , Laure Sansonnet , Julien Chiquet

Covariate-shift generalization, a typical case in out-of-distribution (OOD) generalization, requires a good performance on the unknown test distribution, which varies from the accessible training distribution in the form of covariate shift.…

Machine Learning · Computer Science 2023-10-18 Renzhe Xu , Xingxuan Zhang , Zheyan Shen , Tong Zhang , Peng Cui

We generalize fast Gaussian process leave-one-out formulae to multiple-fold cross-validation, highlighting in turn the covariance structure of cross-validation residuals in both Simple and Universal Kriging frameworks. We illustrate how…

Methodology · Statistics 2023-06-06 David Ginsbourger , Cedric Schärer

Designing a covariance function that represents the underlying correlation is a crucial step in modeling complex natural systems, such as climate models. Geospatial datasets at a global scale usually suffer from non-stationarity and…

Machine Learning · Statistics 2015-07-10 Chintan A. Dalal , Vladimir Pavlovic , Robert E. Kopp