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Chemotherapy appointment scheduling is a challenging problem due to the uncertainty in pre-medication and infusion durations. In this paper, we formulate a two-stage stochastic mixed integer programming model for the chemotherapy…

Optimization and Control · Mathematics 2021-01-20 Nur Banu Demir , Serhat Gul , Melih Celik

Scientific and data science applications are becoming increasingly complex, with growing computational and memory demands. Modern high performance computing (HPC) systems provide high parallelism and heterogeneity across nodes, devices, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-29 Jonas H. Müller Korndörfer , Ali Mohammed , Ahmed Eleliemy , Quentin Guilloteau , Reto Krummenacher , Florina M. Ciorba

Radiotherapy (RT) patient scheduling is a complex operational problem. Current scheduling often relies on manual coordination and can be difficult to adapt to changing clinical demands. This study evaluated the feasibility of using a large…

High-Performance Computing (HPC) job scheduling involves balancing conflicting objectives such as minimizing makespan, reducing wait times, optimizing resource use, and ensuring fairness. Traditional methods, including heuristic-based,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-05 Prachi Jadhav , Hongwei Jin , Ewa Deelman , Prasanna Balaprakash

With the growing use of Large Language Model (LLM)-based tools like ChatGPT, Perplexity, and Gemini across industries, there is a rising need for efficient LLM inference systems. These systems handle requests with a unique two-phase…

Machine Learning · Computer Science 2025-12-02 Agrim Bari , Parikshit Hegde , Gustavo de Veciana

We consider so-called $N$-fold integer programs (IPs) of the form $\max\{c^T x : Ax = b, \ell \leq x \leq u, x \in \mathbb Z^{nt}\}, where $A \in \mathbb Z^{(r+sn)\times nt} consists of $n$ arbitrary matrices $A^{(i)} \in \mathbb Z^{r\times…

Data Structures and Algorithms · Computer Science 2024-07-11 David Fischer , Julian Golak , Matthias Mnich

The significance of last-mile logistics in the healthcare supply chain is growing steadily, especially in pharmacies where the growing prevalence of medication delivery to patients' homes is remarkable. This paper proposes a novel…

Optimization and Control · Mathematics 2024-04-10 Elise Potters , Behzad Mosalla Nezhad , Viktor Huiskes , Erwin Hans , Amin Asadi

We study the problem of optimizing Large Language Model (LLM) inference scheduling to minimize total latency. LLM inference is an online and multi-task service process and also heavily energy consuming by which a pre-trained LLM processes…

Machine Learning · Computer Science 2025-09-03 Zixi Chen , Yinyu Ye , Zijie Zhou

We consider the flow network model to solve the multiprocessor real-time task scheduling problems. Using the flow network model or its generic form, linear programming (LP) formulation, for the problems is not new. However, the previous…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-22 Hyeonjoong Cho , Arvind Easwaran

This paper addresses the challenges of low scheduling efficiency, unbalanced resource allocation, and poor adaptability in ETL (Extract-Transform-Load) processes under heterogeneous data environments by proposing an intelligent scheduling…

Machine Learning · Computer Science 2025-12-16 Kangning Gao , Yi Hu , Cong Nie , Wei Li

Mobility-on-demand systems are transforming the way we think about the transportation of people and goods. Most research effort has been placed on scalability issues for systems with a large number of agents and simple pick-up/drop-off…

Formal Languages and Automata Theory · Computer Science 2022-08-15 Kaier Liang , Cristian-Ioan Vasile

There hardly exists a general solver that is efficient for scheduling problems due to their diversity and complexity. In this study, we develop a two-stage framework, in which reinforcement learning (RL) and traditional operations research…

Artificial Intelligence · Computer Science 2021-03-11 Yongming He , Guohua Wu , Yingwu Chen , Witold Pedrycz

Modern deployment of large language models (LLMs) frequently involves both inference serving and continuous retraining to stay aligned with evolving data and user feedback. Common practices separate these workloads onto distinct servers in…

Artificial Intelligence · Computer Science 2025-07-30 Yufei Li , Zexin Li , Yinglun Zhu , Cong Liu

Finding optimal join orders is among the most crucial steps to be performed by query optimisers. Though extensively studied in data management research, the problem remains far from solved: While query optimisers rely on exhaustive search…

Databases · Computer Science 2025-10-24 Manuel Schönberger , Immanuel Trummer , Wolfgang Mauerer

Mixed integer bilinear programs (MIBLPs) offer tools to resolve robotics motion planning problems with orthogonal rotation matrices or static moment balance, but require long solving times. Recent work utilizing data-driven methods has…

Robotics · Computer Science 2024-08-02 Xuan Lin , Gabriel Ikaika Fernandez , Dennis Hong

Planning in public transportation is traditionally done in a sequential process: After the network design process, the lines and their frequencies are planned. When these are fixed, a timetable is determined and based on the timetable, the…

Optimization and Control · Mathematics 2021-12-07 Philine Schiewe , Anita Schöbel

Mixed-integer optimization is at the core of many online decision-making systems that demand frequent updates of decisions in real time. However, due to their combinatorial nature, mixed-integer linear programs (MILPs) can be difficult to…

Optimization and Control · Mathematics 2026-04-21 Shivi Dixit , Rishabh Gupta , Qi Zhang

With the current high levels of energy consumption of data centers, reducing power consumption by even a small percentage is beneficial. We propose a framework for thermal-aware workload distribution in a data center to reduce cooling power…

Systems and Control · Electrical Eng. & Systems 2023-04-11 Somayye Rostami , Douglas G. Down , George Karakostas

A natural optimization model that formulates many online resource allocation and revenue management problems is the online linear program (LP) in which the constraint matrix is revealed column by column along with the corresponding…

Data Structures and Algorithms · Computer Science 2014-04-10 Shipra Agrawal , Zizhuo Wang , Yinyu Ye

In this work, the online printing shop scheduling problem is considered. This challenging real problem, that appears in the nowadays printing industry, can be seen as a flexible job shop scheduling problem with sequence flexibility in which…

Optimization and Control · Mathematics 2022-02-22 Willian T. Lunardi , Ernesto G. Birgin , Philippe Laborie , Débora P. Ronconi , Holger Voos