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Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

In the modern era, malware is experiencing a significant increase in both its variety and quantity, aligning with the widespread adoption of the digital world. This surge in malware has emerged as a critical challenge in the realm of…

Cryptography and Security · Computer Science 2024-07-16 Amaal F. Alshmarni , Mohammed A. Alliheedi

Neural embedding-based machine learning models have shown promise for predicting novel links in biomedical knowledge graphs. Unfortunately, their practical utility is diminished by their lack of interpretability. Recently, the fully…

Machine Learning · Computer Science 2020-12-11 Simon Ott , Laura Graf , Asan Agibetov , Christian Meilicke , Matthias Samwald

A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

Quantitative Methods · Quantitative Biology 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou

Due to its importance and widespread use in industry, automated testing of REST APIs has attracted major interest from the research community in the last few years. However, most of the work in the literature has been focused on black-box…

Software Engineering · Computer Science 2023-09-18 Andrea Arcuri , Man Zhang , Juan Pablo Galeotti

Making the most use of abundant information in electronic health records (EHR) is rapidly becoming an important topic in the medical domain. Recent work presented a promising framework that embeds entire features in raw EHR data regardless…

Machine Learning · Computer Science 2023-05-11 Eunbyeol Cho , Min Jae Lee , Kyunghoon Hur , Jiyoun Kim , Jinsung Yoon , Edward Choi

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury

Automatic program repair (APR) is crucial to improve software reliability. Recently, neural machine translation (NMT) techniques have been used to fix software bugs automatically. While promising, these approaches have two major…

Software Engineering · Computer Science 2021-09-03 Nan Jiang , Thibaud Lutellier , Lin Tan

Clinical guidelines, typically structured as decision trees, are central to evidence-based medical practice and critical for ensuring safe and accurate diagnostic decision-making. However, it remains unclear whether Large Language Models…

Computation and Language · Computer Science 2025-05-20 Xiaomin Li , Mingye Gao , Yuexing Hao , Taoran Li , Guangya Wan , Zihan Wang , Yijun Wang

Electronic medical records (EMRs) contain the majority of patients' healthcare details. It is an abundant resource for developing an automatic healthcare system. Most of the natural language processing (NLP) studies on EMR processing, such…

Computation and Language · Computer Science 2024-10-01 Hongyi Yuan , Sheng Yu

Mainstream software applications and tools are the configurable platforms with an enormous number of parameters along with their values. Certain settings and possible interactions between these parameters may harden (or soften) the security…

Software Engineering · Computer Science 2020-06-17 Shuvalaxmi Dass , Akbar Siami Namin

Black-box runtime verification methods for cyber-physical systems can be used to discover errors in systems whose inputs and outputs are expressed as signals over time and their correctness requirements are specified in a temporal logic.…

Machine Learning · Computer Science 2024-10-07 Jarkko Peltomäki , Ivan Porres

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

De-identified health data are frequently used in research. As AI advances heighten the risk of re-identification, it is important to respond to concerns about transparency, data privacy, and patient preferences. However, few practical and…

Human-Computer Interaction · Computer Science 2025-11-04 Di Hu , Xi Lu , Yunan Chen , Michelle Keller , An T. Nguyen , Vu Le , Tsung-Ting Kuo , Lucila Ohno-Machado , Kai Zheng

Curriculum learning strategies have been proven to be effective in various applications and have gained significant interest in the field of machine learning. It has the ability to improve the final model's performance and accelerate the…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Asmaa Abbas , Mohamed Gaber , Mohammed M. Abdelsamea

Developing real-time automated test systems for embedded control systems has been a real problem. Some engineers and scientists have used customized software and hardware as a solution, which can be very expensive and time consuming to…

Other Computer Science · Computer Science 2007-05-23 Jon Hawkins , Haung V. Nguyen , Reginald B. Howard

Multimodal artificial intelligence models for endometrial cancer (EC) risk stratification typically optimize aggregate predictive performance but provide limited mechanisms for enforcing mandatory guideline overrides, such as assigning…

Multiagent Systems · Computer Science 2026-04-28 Weiye Dai , Liyun Shi , Zanxiang He , Yuling Ma , Mengyuan Lin , Dianxiang Sun , Liming Nie

Objective: Electronic health records (EHR) represent a rich resource for conducting observational studies, supporting clinical trials, and more. However, much of the relevant information is stored in an unstructured format that makes it…

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