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Understanding the dynamic behavior of proteins is critical to elucidating their functional mechanisms, yet generating realistic, temporally coherent trajectories of protein ensembles remains a significant challenge. In this work, we…

Biomolecules · Quantitative Biology 2025-11-11 Yaoyao Xu , Di Wang , Zihan Zhou , Tianshu Yu , Mingchen Chen

The characterization of cattle demographics and especially movements is an essential component in the modeling of dynamics in cattle systems, yet for cattle systems of the United States (US), this is missing. Through a large-scale maximum…

Applications · Statistics 2014-08-20 Phillip Schumm , Caterina Scoglio , H Morgan Scott

Autonomous agents require the capability to identify dynamic objects in their environment for safe planning and navigation. Incomplete and erroneous dynamic detections jeopardize the agent's ability to accomplish its task. Dynamic detection…

Robotics · Computer Science 2024-10-25 Vedant Bhandari , Jasmin James , Tyson Phillips , P. Ross McAree

One of the issues of e-learning web based application is to understand how the learner interacts with an e-learning application to perform a given task. This study proposes a methodology to analyze learner mouse movement in order to infer…

Human-Computer Interaction · Computer Science 2014-05-22 Elbahi Anis , Mohamed Ali Mahjoub , Mohamed Nazih Omri

Understanding disease dynamics is crucial for managing wildlife populations and assessing spillover risk to domestic animals and humans, but infection data on free-ranging animals are difficult to obtain. Because pathogen and parasite…

Quantitative Methods · Quantitative Biology 2025-09-26 Dongmin Kim , Théo Michelot , Katherine Mertes , Jared A. Stabach , John Fieberg

Active learning seeks to reduce the amount of data required to fit the parameters of a model, thus forming an important class of techniques in modern machine learning. However, past work on active learning has largely overlooked latent…

Machine Learning · Computer Science 2024-02-20 Aditi Jha , Zoe C. Ashwood , Jonathan W. Pillow

The objective of transfer learning is to enhance estimation and inference in a target data by leveraging knowledge gained from additional sources. Recent studies have explored transfer learning for independent observations in complex,…

Machine Learning · Statistics 2025-04-23 Mingliang Ma Abolfazl Safikhani

The conformational kinetics of enzymes can be reliably revealed when they are governed by Markovian dynamics. Hidden Markov Models (HMMs) are appropriate especially in the case of conformational states that are hardly distinguishable.…

Quantitative Methods · Quantitative Biology 2009-02-05 A. Kovalev , N. Zarrabi , F. Werz , M. Boersch , Z. Ristic , H. Lill , D. Bald , C. Tietz , J. Wrachtrup

Trajectory prediction is crucial to advance autonomous driving, improving safety, and efficiency. Although end-to-end models based on deep learning have great potential, they often do not consider vehicle dynamic limitations, leading to…

Robotics · Computer Science 2025-08-20 Alexander Fertig , Lakshman Balasubramanian , Michael Botsch

Markerless motion capture has become an active field of research in computer vision in recent years. Its extensive applications are known in a great variety of fields, including computer animation, human motion analysis, biomedical…

Computer Vision and Pattern Recognition · Computer Science 2022-01-10 Doan Duy Vo , Russell Butler

A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is…

Machine Learning · Computer Science 2022-07-26 Taha Ceritli , Andrew P. Creagh , David A. Clifton

Hidden Markov Models (HMMs) are powerful tools for modeling sequential data, where the underlying states evolve in a stochastic manner and are only indirectly observable. Traditional HMM approaches are well-established for linear sequences,…

Machine Learning · Statistics 2024-06-05 Farzan Vafa , Sahand Hormoz

We propose a unified framework that extends the inference methods for classical hidden Markov models to continuous settings, where both the hidden states and observations occur in continuous time. Two different settings are analyzed: hidden…

Methodology · Statistics 2021-06-18 Qingcan Wang , Weinan E

Human motion plays an important role in many fields. Large databases exist that store and make available recordings of human motions. However, annotating each motion with multiple labels is a cumbersome and error-prone process. This…

Machine Learning · Computer Science 2016-05-06 Matthias Plappert

Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying…

Due to the unparallelizable nature of the autoregressive factorization, AutoRegressive Translation (ART) models have to generate tokens sequentially during decoding and thus suffer from high inference latency. Non-AutoRegressive Translation…

Computation and Language · Computer Science 2019-09-17 Zhuohan Li , Zi Lin , Di He , Fei Tian , Tao Qin , Liwei Wang , Tie-Yan Liu

Unsupervised learning aims at the discovery of hidden structure that drives the observations in the real world. It is essential for success in modern machine learning. Latent variable models are versatile in unsupervised learning and have…

Machine Learning · Computer Science 2016-06-13 Furong Huang

Traditional hidden Markov models have been a useful tool to understand and model stochastic dynamic data; in the case of non-Gaussian data, models such as mixture of Gaussian hidden Markov models can be used. However, these suffer from the…

Machine Learning · Statistics 2023-05-16 Carlos Puerto-Santana , Concha Bielza , Pedro Larrañaga , Gustav Eje Henter

Understanding species-habitat associations is fundamental to ecological sciences and for species conservation. Consequently, various statistical approaches have been designed to infer species-habitat associations. Due to their conceptual…

Scientists often use observational time series data to study complex natural processes, but regression analyses often assume simplistic dynamics. Recent advances in deep learning have yielded startling improvements to the performance of…

Machine Learning · Computer Science 2023-04-21 Cory Shain , William Schuler