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We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…
Graphical LASSO (GLASSO) is a widely used method for estimating sparse precision matrices and learning undirected graphical models in high-dimensional settings. Because GLASSO penalizes entries of the precision matrix directly, however, it…
Semi-supervised semantic segmentation involves assigning pixel-wise labels to unlabeled images at training time. This is useful in a wide range of real-world applications where collecting pixel-wise labels is not feasible in time or cost.…
Semi-supervised semantic segmentation relieves the reliance on large-scale labeled data by leveraging unlabeled data. Recent semi-supervised semantic segmentation approaches mainly resort to pseudo-labeling methods to exploit unlabeled…
Gaussian graphical models typically assume a homogeneous structure across all subjects, which is often restrictive in applications. In this article, we propose a weighted pseudo-likelihood approach for graphical modeling which allows…
The iterations of many sparse estimation algorithms are comprised of a fixed linear filter cascaded with a thresholding nonlinearity, which collectively resemble a typical neural network layer. Consequently, a lengthy sequence of algorithm…
Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…
Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…
We address the problem of estimating causal effects from observational data in the presence of network confounding, a setting where both treatment assignment and observed outcomes of individuals may be influenced by their neighbors within a…
Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it is a challenging task due to low availability of public…
Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…
Semi-supervised multi-organ medical image segmentation aids physicians in improving disease diagnosis and treatment planning and reduces the time and effort required for organ annotation.Existing state-of-the-art methods train the labeled…
Large neural networks pretrained on web-scale corpora are central to modern machine learning. In this paradigm, the distribution of the large, heterogeneous pretraining data rarely matches that of the application domain. This work considers…
Semi-supervised learning has substantially advanced medical image segmentation since it alleviates the heavy burden of acquiring the costly expert-examined annotations. Especially, the consistency-based approaches have attracted more…
Kernel methods have been extensively utilized in machine learning for classification and prediction tasks due to their ability to capture complex non-linear data patterns. However, single kernel approaches are inherently limited, as they…
A novel design procedure for practical hierarchical distribution matchers (HiDMs) in probabilistically shaped constellation systems is presented. The proposed approach enables the determination of optimal parameters for any target…
Flexible estimation of heterogeneous treatment effects lies at the heart of many statistical challenges, such as personalized medicine and optimal resource allocation. In this paper, we develop a general class of two-step algorithms for…
We propose a partially linear additive Gaussian graphical model (PLA-GGM) for the estimation of associations between random variables distorted by observed confounders. Model parameters are estimated using an $L_1$-regularized maximal…
In partial multi-label learning (PML), each data example is equipped with a candidate label set, which consists of multiple ground-truth labels and other false-positive labels. Recently, graph-based methods, which demonstrate a good ability…
We present a probabilistic graphical model formulation for the graph clustering problem. This enables to locally represent uncertainty of image partitions by approximate marginal distributions in a mathematically substantiated way, and to…