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Preference alignment is an essential step in adapting large language models (LLMs) to human values, but existing approaches typically depend on costly human annotations or large-scale API-based models. We explore whether a weak LLM can…

Computation and Language · Computer Science 2026-03-06 Amirabbas Afzali , Myeongho Jeon , Maria Brbic

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Machine Learning · Computer Science 2025-09-29 Ziqing Wang , Yibo Wen , William Pattie , Xiao Luo , Weimin Wu , Jerry Yao-Chieh Hu , Abhishek Pandey , Han Liu , Kaize Ding

The remarkable performance of Large Language Models (LLMs) highly relies on crafted prompts. However, manual prompt engineering is a laborious process, creating a core bottleneck for practical application of LLMs. This phenomenon has led to…

Computation and Language · Computer Science 2025-11-21 Qing Zhang , Bing Xu , Xudong Zhang , Yifan Shi , Yang Li , Chen Zhang , Yik Chung Wu , Ngai Wong , Yijie Chen , Hong Dai , Xiansen Chen , Mian Zhang

The last year has witnessed the rapid progress of large language models (LLMs) across diverse domains. Among them, CodeLLMs have garnered particular attention because they can not only assist in completing various programming tasks but also…

Artificial Intelligence · Computer Science 2024-10-25 Yibo Miao , Bofei Gao , Shanghaoran Quan , Junyang Lin , Daoguang Zan , Jiaheng Liu , Jian Yang , Tianyu Liu , Zhijie Deng

Aligning large language models (LLMs) is a central objective of post-training, often achieved through reward modeling and reinforcement learning methods. Among these, direct preference optimization (DPO) has emerged as a widely adopted…

Computation and Language · Computer Science 2026-03-03 Aladin Djuhera , Farhan Ahmed , Swanand Ravindra Kadhe , Syed Zawad , Heiko Ludwig , Holger Boche

Multi-objective preference alignment of large language models (LLMs) is critical for developing AI systems that are more configurable, personalizable, helpful, and safe. However, optimizing model outputs to satisfy diverse objectives with…

Computation and Language · Computer Science 2025-03-04 Raghav Gupta , Ryan Sullivan , Yunxuan Li , Samrat Phatale , Abhinav Rastogi

Preference optimization (PO) is indispensable for large language models (LLMs), with methods such as direct preference optimization (DPO) and proximal policy optimization (PPO) achieving great success. A common belief is that DPO is…

Machine Learning · Computer Science 2026-05-18 Yue Wang , Qizhou Wang , Zizhuo Zhang , Gang Niu , Bo Han , Masashi Sugiyama

While astonishingly capable, large Language Models (LLM) can sometimes produce outputs that deviate from human expectations. Such deviations necessitate an alignment phase to prevent disseminating untruthful, toxic, or biased information.…

Artificial Intelligence · Computer Science 2024-10-30 Long Tan Le , Han Shu , Tung-Anh Nguyen , Choong Seon Hong , Nguyen H. Tran

Aligning large language models (LLMs) with human values and intentions is crucial for their utility, honesty, and safety. Reinforcement learning from human feedback (RLHF) is a popular approach to achieve this alignment, but it faces…

Machine Learning · Computer Science 2025-07-22 Junkang Wu , Xue Wang , Zhengyi Yang , Jiancan Wu , Jinyang Gao , Bolin Ding , Xiang Wang , Xiangnan He

A common technique for aligning large language models (LLMs) relies on acquiring human preferences by comparing multiple generations conditioned on a fixed context. This method, however, relies solely on pairwise comparisons, where the…

Computation and Language · Computer Science 2025-01-09 Hritik Bansal , Ashima Suvarna , Gantavya Bhatt , Nanyun Peng , Kai-Wei Chang , Aditya Grover

The rapidly increasing capabilities of large language models (LLMs) raise an urgent need to align AI systems with diverse human preferences to simultaneously enhance their usefulness and safety, despite the often conflicting nature of these…

Machine Learning · Computer Science 2024-03-06 Zixuan Liu , Xiaolin Sun , Zizhan Zheng

As large language models (LLMs) are increasingly applied across various domains, enhancing safety while maintaining the helpfulness of LLMs has become a critical challenge. Recent studies solve this problem through safety-constrained online…

Computation and Language · Computer Science 2025-06-04 Yupeng Qi , Ziyu Lyu , Min Yang , Yanlin Wang , Lu Bai , Lixin Cui

The recent success in using human preferences to align large language models (LLMs) has significantly improved their performance in various downstream tasks, such as question answering, mathematical reasoning, and code generation. However,…

Machine Learning · Computer Science 2026-05-18 Xiaoqiang Lin , Arun Verma , Zhongxiang Dai , Daniela Rus , See-Kiong Ng , Bryan Kian Hsiang Low

Direct Preference Optimization (DPO) has emerged as a prominent algorithm for the direct and robust alignment of Large Language Models (LLMs) with human preferences, offering a more straightforward alternative to the complex Reinforcement…

Computation and Language · Computer Science 2024-12-10 Junru Lu , Jiazheng Li , Siyu An , Meng Zhao , Yulan He , Di Yin , Xing Sun

This paper presents Perceptual Preference Optimization (PerPO), a perception alignment method aimed at addressing the visual discrimination challenges in generative pre-trained multimodal large language models (MLLMs). To align MLLMs with…

Artificial Intelligence · Computer Science 2025-02-10 Zining Zhu , Liang Zhao , Kangheng Lin , Jinze Yang , En Yu , Chenglong Liu , Haoran Wei , Jianjian Sun , Zheng Ge , Xiangyu Zhang

Large language models (LLMs) have recently gained much attention in building autonomous agents. However, the performance of current LLM-based web agents in long-horizon tasks is far from optimal, often yielding errors such as repeatedly…

Computation and Language · Computer Science 2025-04-01 Hyungjoo Chae , Namyoung Kim , Kai Tzu-iunn Ong , Minju Gwak , Gwanwoo Song , Jihoon Kim , Sunghwan Kim , Dongha Lee , Jinyoung Yeo

Direct Preference Optimization (DPO) improves the alignment of large language models (LLMs) with human values by training directly on human preference datasets, eliminating the need for reward models. However, due to the presence of…

Artificial Intelligence · Computer Science 2024-06-11 Biqing Qi , Pengfei Li , Fangyuan Li , Junqi Gao , Kaiyan Zhang , Bowen Zhou

Preference learning extends the performance of Code LLMs beyond traditional supervised fine-tuning by leveraging relative quality comparisons. In existing approaches, a set of n candidate solutions is evaluated based on test case success…

Computation and Language · Computer Science 2025-10-10 Jie Wu , Haoling Li , Xin Zhang , Xiao Liu , Yangyu Huang , Jianwen Luo , Yizhen Zhang , Zuchao Li , Ruihang Chu , Yujiu Yang , Scarlett Li

Aligning large language models (LLMs) with human preferences is a critical challenge in AI research. While methods like Reinforcement Learning from Human Feedback (RLHF) and Direct Preference Optimization (DPO) are widely used, they often…

Computation and Language · Computer Science 2026-05-19 Xuan Qi , Rongwu Xu , Zhijing Jin

Recent advances in large language models (LLMs) have greatly improved their reasoning and decision-making abilities when deployed as agents. Richer reasoning, however, often comes at the cost of longer chain of thought (CoT), hampering…

Computation and Language · Computer Science 2025-11-20 Sirui Chen , Mengshi Zhao , Lei Xu , Yuying Zhao , Beier Zhu , Hanwang Zhang , Shengjie Zhao , Chaochao Lu