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Cortical circuits are characterized by exquisitely complex connectivity patterns that emerge during development from undifferentiated networks. The development of these circuits is governed by a combination of precise molecular cues that…

Neurons and Cognition · Quantitative Biology 2020-09-15 Joseph Olson , Gabriel Kreiman

Neural oscillations have long been considered important markers of interaction across brain regions, yet identifying coordinated oscillatory activity from high-dimensional multiple-electrode recordings remains challenging. We sought to…

Methodology · Statistics 2025-12-30 Heejong Bong , Valérie Ventura , Eric A. Yttri , Matthew A. Smith , Robert E. Kass

It is well known that synchronization patterns and coherence have a major role in the functioning of brain networks, both in pathological and in healthy states. In particular, in the perception of sound, one can observe an increase in…

Adaptation and Self-Organizing Systems · Physics 2024-02-01 Jakub Sawicki , Eckehard Schöll

Canonical Correlation Analysis (CCA) is a method for analyzing pairs of random vectors; it learns a sequence of paired linear transformations such that the resultant canonical variates are maximally correlated within pairs while…

Methodology · Statistics 2023-08-23 Daniel Kessler , Elizaveta Levina

Functional connectivity of cognitive tasks allows researchers to analyse the interaction mapping occurring between different regions of the brain using electroencephalography (EEG) signals. Standard practice in functional connectivity…

Human-Computer Interaction · Computer Science 2019-07-23 Saugat Bhattacharyya , Mitsuhiro Hayashibe

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

Statistics Theory · Mathematics 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen

Comparing different neural network representations and determining how representations evolve over time remain challenging open questions in our understanding of the function of neural networks. Comparing representations in neural networks…

Machine Learning · Statistics 2018-10-25 Ari S. Morcos , Maithra Raghu , Samy Bengio

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Canonical correlation analysis (CCA) is a state-of-the-art method for frequency recognition in steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems. Various extended methods have been developed, and…

Neurons and Cognition · Quantitative Biology 2018-07-03 Yangsong Zhang , Erwei Yin , Fali Li , Yu Zhang , Toshihisa Tanaka , Qibin Zhao , Yan Cui , Peng Xu , Dezhong Yao , Daqing Guo

Traditional Topological Data Analysis (TDA) methods, such as Persistent Homology (PH), rely on distance measures (e.g., cross-correlation, partial correlation, coherence, and partial coherence) that are symmetric by definition. While useful…

Neurons and Cognition · Quantitative Biology 2024-07-19 Anass B. El-Yaagoubi , Moo K. Chung , Hernando Ombao

Electrocorticography (ECoG) provides direct measurements of synchronized postsynaptic potentials at the exposed cortical surface. Patterns of signal covariance across ECoG sensors have been associated with diverse cognitive functions and…

Neurons and Cognition · Quantitative Biology 2017-06-20 Richard F. Betzel , John D. Medaglia , Ari E. Kahn , Jonathan Soffer , Daniel R. Schonhaut , Danielle S. Bassett

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

We propose a geometric model-free causality measurebased on multivariate delay embedding that can efficiently detect linear and nonlinear causal interactions between time series with no prior information. We then exploit the proposed causal…

Neural and Evolutionary Computing · Computer Science 2016-07-26 Saba Emrani , Hamid Krim

Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…

Neurons and Cognition · Quantitative Biology 2022-11-28 Qiang Li , Greg Ver Steeg , Shujian Yu , Jesus Malo

Coherence and phase synchronization between time series corresponding to different spatial locations are usually interpreted as indicators of the connectivity between locations. In neurophysiology, time series of electric neuronal activity…

Methodology · Statistics 2007-07-12 Roberto D. Pascual-Marqui

This work is concerned with the limiting spectral distribution of rank-based dependency measures in high dimensions. We provide distribution-free results for multivariate empirical versions of Kendall's $\tau$ and Spearman's $\rho$ in a…

Statistics Theory · Mathematics 2025-08-22 Nina Dörnemann , Michael Fleermann , Johannes Heiny

The cortico-spinal neural pathway is fundamental for motor control and movement execution, and in humans it is typically studied using concurrent electroencephalography (EEG) and electromyography (EMG) recordings. However, current…

Neurons and Cognition · Quantitative Biology 2024-12-23 Shihan Ma , Bo Hu , Tianyu Jia , Alexander Kenneth Clarke , Blanka Zicher , Arnault H. Caillet , Dario Farina , Jose C. Principe

The brain's structural connectome supports signal propagation between neuronal elements, shaping diverse coactivation patterns that can be captured as functional connectivity. While the link between structure and function remains an ongoing…

Neurons and Cognition · Quantitative Biology 2022-07-11 Yaqian Yang , Zhiming Zheng , Longzhao Liu , Hongwei Zheng , Yi Zhen , Yi Zheng , Xin Wang , Shaoting Tang

Alterations in functional brain connectivity characterize neurodegenerative disorders such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). As a non-invasive and cost-effective technique, electroencephalography (EEG) is…

Applications · Statistics 2025-11-19 Paolo Victor Redondo , Raphaël Huser , Hernando Ombao