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In the field of chemistry, the objective is to create novel molecules with desired properties, facilitating accurate property predictions for applications such as material design and drug screening. However, existing graph deep learning…

Machine Learning · Computer Science 2024-08-28 Sakhinana Sagar Srinivas , Venkataramana Runkana

Atomistic simulations of electrochemical interfaces remain challenging due to the long time scales required to adequately sample the structure of the electric double layer. The emergence of efficient, short-range machine learning…

Free energy profiles serve as a fundamental bridge between microscopic atomic fluctuations and macroscopic thermodynamic observables. Estimating the free energy profile along a reaction coordinate, referred to as the potential of mean force…

This paper surveys benchmarking principles, machine learning devices including GPUs, FPGAs, and ASICs, and deep learning software frameworks. It also reviews these technologies with respect to benchmarking from the perspectives of a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-02-19 Wei Dai , Daniel Berleant

Alumina and aluminum oxyhydroxides underpin chemical-engineering technologies from heterogeneous catalysis, corrosion protection, functional coatings, energy-storage devices, to biomedical components. Yet molecular models that predictively…

Machine learning (ML) can facilitate efficient thermoelectric (TE) material discovery essential to address the environmental crisis. However, ML models often suffer from poor experimental generalizability despite high metrics. This study…

Materials Science · Physics 2026-02-03 Shoeb Athar , Adrien Mecibah , Philippe Jund

With the growing availability of machine-learned interatomic potential (MLIP) models for materials simulations, there is an increasing demand for robust, automated, and chemically insightful benchmarking methodologies. In response, we here…

Materials Science · Physics 2025-11-21 Natascia L. Fragapane , Volker L. Deringer

The particle-flow (PF) algorithm, which infers particles based on tracks and calorimeter clusters, is of central importance to event reconstruction in the CMS experiment at the CERN LHC, and has been a focus of development in light of…

Data Analysis, Statistics and Probability · Physics 2023-04-03 Farouk Mokhtar , Joosep Pata , Javier Duarte , Eric Wulff , Maurizio Pierini , Jean-Roch Vlimant

Machine-learned interatomic potentials (MLIPs) and force fields (i.e. interaction laws for atoms and molecules) are typically trained on limited data-sets that cover only a very small section of the full space of possible input structures.…

Numerical Analysis · Mathematics 2022-09-13 Christoph Ortner , Yangshuai Wang

Predicting polymer glass transition temperatures (Tg) with first-principles fidelity has long remained out of reach, as cooling multi-thousand-atom systems over a broad temperature range at acceptable rates exceeds the computational limits…

Materials Science · Physics 2026-01-27 Ashutosh Srivastava , Sakshi Agarwal , Shivank Shukla , Harikrishna Sahu , Rampi Ramprasad

The development of reliable and extensible molecular mechanics (MM) force fields -- fast, empirical models characterizing the potential energy surface of molecular systems -- is indispensable for biomolecular simulation and computer-aided…

Universal Machine Learning Interactomic Potentials (MLIPs) enable accelerated simulations for materials discovery. However, current research efforts fail to impactfully utilize MLIPs due to: 1. Overreliance on Density Functional Theory…

Materials Science · Physics 2025-02-07 Santiago Miret , Kin Long Kelvin Lee , Carmelo Gonzales , Sajid Mannan , N. M. Anoop Krishnan

Machine-learning interatomic potentials have revolutionized materials modeling at the atomic scale. Thanks to these, it is now indeed possible to perform simulations of \abinitio quality over very large time and length scales. More…

Materials Science · Physics 2024-07-23 Haochen Yu , Matteo Giantomassi , Giuliana Materzanini , Junjie Wang , Gian-Marco Rignanese

In general-purpose particle detectors, the particle-flow algorithm may be used to reconstruct a comprehensive particle-level view of the event by combining information from the calorimeters and the trackers, significantly improving the…

Data Analysis, Statistics and Probability · Physics 2021-06-10 Joosep Pata , Javier Duarte , Jean-Roch Vlimant , Maurizio Pierini , Maria Spiropulu

AI for science (AI4S) is an emerging research field that aims to enhance the accuracy and speed of scientific computing tasks using machine learning methods. Traditional AI benchmarking methods struggle to adapt to the unique challenges…

Machine Learning · Computer Science 2023-08-14 Yatao Li , Wanling Gao , Lei Wang , Lixin Sun , Zun Wang , Jianfeng Zhan

Machine learning force fields possess unprecedented potential in achieving both accuracy and efficiency in molecular simulations. Nevertheless, their application in organic systems is often hindered by structural collapse during simulation…

Computational Physics · Physics 2026-02-03 Junbao Hu , Dingyu Hou , Jian Jiang

Machine learning interatomic potentials (MLIPs) have revolutionized molecular and materials modeling, but existing benchmarks suffer from data leakage, limited transferability, and an over-reliance on error-based metrics tied to specific…

Rapid adoption of machine learning (ML) technologies has led to a surge in power consumption across diverse systems, from tiny IoT devices to massive datacenter clusters. Benchmarking the energy efficiency of these systems is crucial for…

Universal machine-learning interatomic potentials (uMLIPs) enable reactive molecular simulations with near-DFT accuracy, yet applying them efficiently to large, realistic condensed-phase systems remains computationally demanding. Here we…

Materials Science · Physics 2026-03-25 Yu Miyazaki , Atsuhiro Tomita , Akihide Hayashi , So Takamoto , Mizuki Takemoto , Hodaka Mori

The potential to utilize metal-organic frameworks as a replacement for rare earth materials as well as in technological applications has prompted increased interested in this material class. The simulation of organic materials, including…

Materials Science · Physics 2026-05-01 Alexander C. Tyner , Avinash Pathapati , Alexander V. Balatsky
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