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Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis one, two, and three years prior to diagnosis using routinely collected electronic health record (EHR) data, and to benchmark their…

Machine Learning · Computer Science 2026-01-05 Zhuqi Miao , Sujan Ravi , Abdulaziz Ahmed

Objective: Machine learning (ML) predictive models are often developed without considering downstream value trade-offs and clinical interpretability. This paper introduces a cost-aware prediction (CAP) framework that combines cost-benefit…

Machine Learning · Computer Science 2025-11-20 Yinan Yu , Falk Dippel , Christina E. Lundberg , Martin Lindgren , Annika Rosengren , Martin Adiels , Helen Sjöland

Alzheimer's disease (AD) is the fifth-leading cause of death among Americans aged 65 and older. Screening and early detection of AD and related dementias (ADRD) are critical for timely intervention and for identifying clinical trial…

Artificial Intelligence · Computer Science 2024-05-29 Jiankun Wang , Sumyeong Ahn , Taykhoom Dalal , Xiaodan Zhang , Weishen Pan , Qiannan Zhang , Bin Chen , Hiroko H. Dodge , Fei Wang , Jiayu Zhou

Machine learning (ML) provides powerful tools for predictive modeling. ML's popularity stems from the promise of sample-level prediction with applications across a variety of fields from physics and marketing to healthcare. However, if not…

The management of chronic Heart Failure (HF) presents significant challenges in modern healthcare, requiring continuous monitoring, early detection of exacerbations, and personalized treatment strategies. In this paper, we present a…

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Advances in IoT technologies combined with new algorithms have enabled the collection and processing of high-rate multi-source data streams that quantify human behavior in a fine-grained level and can lead to deeper insights on individual…

Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…

Machine Learning · Computer Science 2023-10-18 Tomas M. Bosschieter , Zifei Xu , Hui Lan , Benjamin J. Lengerich , Harsha Nori , Ian Painter , Vivienne Souter , Rich Caruana

The provision of social care applications is crucial for elderly people to improve their quality of life and enables operators to provide early interventions. Accurate predictions of user dropouts in healthy ageing applications are…

Machine Learning · Computer Science 2023-09-11 Christos Chrysanthos Nikolaidis , Vasileios Perifanis , Nikolaos Pavlidis , Pavlos S. Efraimidis

Controlling infectious diseases is a major health priority because they can spread and infect humans, thus evolving into epidemics or pandemics. Therefore, early detection of infectious diseases is a significant need, and many researchers…

Machine Learning · Computer Science 2022-06-16 Eman Yahia Alqaissi , Fahd Saleh Alotaibi , Muhammad Sher Ramzan

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

A high-risk pregnancy is a pregnancy complicated by factors that can adversely affect the outcomes of the mother or the infant. Health insurers use algorithms to identify members who would benefit from additional clinical support. This work…

Accurate fetal birth weight prediction is a cornerstone of prenatal care, yet traditional methods often rely on imaging technologies that remain inaccessible in resource-limited settings. This study presents a novel machine learning-based…

Background: The rapid advancement of Machine Learning (ML) represents novel opportunities to enhance public health research, surveillance, and decision-making. However, there is a lack of comprehensive understanding of algorithmic bias,…

Machine Learning · Computer Science 2024-09-04 Shaina Raza , Arash Shaban-Nejad , Elham Dolatabadi , Hiroshi Mamiya

Deep learning has been widely applied in neuroimaging, including predicting brain-phenotype relationships from magnetic resonance imaging (MRI) volumes. MRI data usually requires extensive preprocessing prior to modeling, but variation…

Machine Learning · Computer Science 2023-10-17 Xinhui Li , Alex Fedorov , Mrinal Mathur , Anees Abrol , Gregory Kiar , Sergey Plis , Vince Calhoun

Machine learning inference pipelines commonly encountered in data science and industries often require real-time responsiveness due to their user-facing nature. However, meeting this requirement becomes particularly challenging when certain…

Databases · Computer Science 2024-05-21 Chaokun Chang , Eric Lo , Chunxiao Ye

Machine learning (ML) is now commonplace, powering data-driven applications in various organizations. Unlike the traditional perception of ML in research, ML production pipelines are complex, with many interlocking analytical components…

Databases · Computer Science 2021-03-31 Doris Xin , Hui Miao , Aditya Parameswaran , Neoklis Polyzotis

Time-series learning is the bread and butter of data-driven *clinical decision support*, and the recent explosion in ML research has demonstrated great potential in various healthcare settings. At the same time, medical time-series problems…

Machine Learning · Computer Science 2023-10-31 Daniel Jarrett , Jinsung Yoon , Ioana Bica , Zhaozhi Qian , Ari Ercole , Mihaela van der Schaar

Electronic health record (EHR) data are increasingly used for biomedical research, but these data have recognized data quality challenges. Data validation is necessary to use EHR data with confidence, but limited resources typically make…

Recent advancements in software and hardware technologies have enabled the use of AI/ML models in everyday applications has significantly improved the quality of service rendered. However, for a given application, finding the right AI/ML…

Machine Learning · Computer Science 2023-04-19 Haoxiang Zhang , Juliana Freire , Yash Garg