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The Genomic Foundation Model (GFM) paradigm is expected to facilitate the extraction of generalizable representations from massive genomic data, thereby enabling their application across a spectrum of downstream applications. Despite…

Genomics · Quantitative Biology 2024-06-06 Zicheng Liu , Jiahui Li , Siyuan Li , Zelin Zang , Cheng Tan , Yufei Huang , Yajing Bai , Stan Z. Li

Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…

Other Quantitative Biology · Quantitative Biology 2025-01-29 Wang Liang

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…

Machine Learning · Statistics 2024-12-04 Mitja Briscik , Gabriele Tazza , Marie-Agnes Dillies , László Vidács , Sébastien Dejean

Dynamic multi-objective optimization (DMOO) has recently attracted increasing interest from both academic researchers and engineering practitioners, as numerous real-world applications that evolve over time can be naturally formulated as…

Neural and Evolutionary Computing · Computer Science 2026-01-06 Chang Shao , Qi Zhao , Nana Pu , Shi Cheng , Jing Jiang , Yuhui Shi

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

Large reasoning models (LRMs) increasingly rely on step-by-step Chain-of-Thought (CoT) reasoning to improve task performance, particularly in high-resource languages such as English. While recent work has examined final-answer accuracy in…

Computation and Language · Computer Science 2025-10-13 Raoyuan Zhao , Yihong Liu , Hinrich Schütze , Michael A. Hedderich

Ontology matching (OM) plays an essential role in enabling semantic interoperability and integration across heterogeneous knowledge sources, particularly in the biomedical domain which contains numerous complex concepts related to diseases…

Artificial Intelligence · Computer Science 2026-04-03 Yiping Song , Jiaoyan Chen , Renate A. Schmidt

Deep Research Agents (DRAs) generate citation-rich reports via multi-step search and synthesis, yet existing benchmarks mainly target text-only settings or short-form multimodal QA, missing end-to-end multimodal evidence use. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Peizhou Huang , Zixuan Zhong , Zhongwei Wan , Donghao Zhou , Samiul Alam , Xin Wang , Zexin Li , Zhihao Dou , Li Zhu , Jing Xiong , Chaofan Tao , Yan Xu , Dimitrios Dimitriadis , Tuo Zhang , Mi Zhang

Ontology Matching (OM) plays an important role in many domains such as bioinformatics and the Semantic Web, and its research is becoming increasingly popular, especially with the application of machine learning (ML) techniques. Although the…

Artificial Intelligence · Computer Science 2023-07-25 Yuan He , Jiaoyan Chen , Hang Dong , Ernesto Jiménez-Ruiz , Ali Hadian , Ian Horrocks

The Common Objects in Context (COCO) dataset has been instrumental in benchmarking object detectors over the past decade. Like every dataset, COCO contains subtle errors and imperfections stemming from its annotation procedure. With the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Shweta Singh , Aayan Yadav , Jitesh Jain , Humphrey Shi , Justin Johnson , Karan Desai

Biological AI models increasingly predict complex cellular responses, yet their learned representations remain disconnected from the molecular processes they aim to capture. We present CDT-III, which extends mechanism-oriented AI across the…

Machine Learning · Computer Science 2026-03-27 Nobuyuki Ota

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

We present the first comprehensive study on automatic knowledge base construction for two prevalent commonsense knowledge graphs: ATOMIC (Sap et al., 2019) and ConceptNet (Speer et al., 2017). Contrary to many conventional KBs that store…

Computation and Language · Computer Science 2019-06-18 Antoine Bosselut , Hannah Rashkin , Maarten Sap , Chaitanya Malaviya , Asli Celikyilmaz , Yejin Choi

Existing benchmarks for multimodal learning in Earth science offer limited, siloed coverage of Earth's spheres and their cross-sphere interactions, typically restricting evaluation to the human-activity sphere of atmosphere and to at most…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Fengxiang Wang , Mingshuo Chen , Xuming He , Yi-Fan Zhang , Yueying Li , Feng Liu , Zijie Guo , Zhenghao Hu , Jiong Wang , Jingyi Xu , Zhangrui Li , Junchao Gong , Di Wang , Fenghua Ling , Ben Fei , Weijia Li , Long Lan , Wenjing Yang

Mathematical reasoning is a hallmark of human intelligence, and whether large language models (LLMs) can meaningfully perform it remains a central question in artificial intelligence and cognitive science. As LLMs are increasingly…

Computation and Language · Computer Science 2026-04-03 Linyang He , Qiyao Yu , Hanze Dong , Baohao Liao , Xinxing Xu , Micah Goldblum , Jiang Bian , Nima Mesgarani

In recent years, large language models (LLMs) have demonstrated significant potential across various natural language processing (NLP) tasks. However, their performance in domain-specific applications and non-English languages remains less…

Computation and Language · Computer Science 2025-10-01 Dragos-Dumitru Ghinea , Adela-Nicoleta Corbeanu , Adrian-Marius Dumitran

Entity Matching (EM)--the task of determining whether two data records refer to the same real-world entity--is a core task in data integration. Recent advances in deep learning have set a new standard for EM, particularly through…

Databases · Computer Science 2026-03-18 Nicholas Pulsone , Roee Shraga , Gregory Goren

Multi-omics research has enhanced our understanding of cancer heterogeneity and progression. Investigating molecular data through multi-omics approaches is crucial for unraveling the complex biological mechanisms underlying cancer, thereby…

Large Vision-Language Models (LVLMs) have recently demonstrated amazing success in multi-modal tasks, including advancements in Multi-modal Chain-of-Thought (MCoT) reasoning. Despite these successes, current benchmarks still follow a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Zihui Cheng , Qiguang Chen , Jin Zhang , Hao Fei , Xiaocheng Feng , Wanxiang Che , Min Li , Libo Qin