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Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

The identification of repeating patterns in discrete grids is rudimentary within symbolic reasoning, algorithm synthesis and structural optimization across diverse computational domains. Although statistical approaches targeting noisy data…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Sushish Baral , Paulo Garcia , Warisa Sritriratanarak

Natural generation allows Large Language Models (LLMs) to produce free-form responses with rich reasoning, yet the lack of structure makes outputs difficult to verify. Conversely, constrained decoding ensures standardized formats but can…

Computation and Language · Computer Science 2026-05-29 Ngoc Trinh Hung Nguyen , Alonso Silva , Laith Zumot , Liubov Tupikina , Armen Aghasaryan , Mehwish Alam

We introduce a general framework for analyzing learning algorithms based on the notion of self-regularization, which captures implicit complexity control without requiring explicit regularization. This is motivated by previous observations…

Machine Learning · Statistics 2026-03-19 Max Schölpple , Liu Fanghui , Ingo Steinwart

Scaling test-time compute via parallel sampling can substantially improve LLM reasoning, but is often limited by Best-of-N selection quality. Generative selection methods, such as GenSelect, address this bottleneck, yet strong selection…

Genetic algorithms constitute a family of black-box optimization algorithms, which take inspiration from the principles of biological evolution. While they provide a general-purpose tool for optimization, their particular instantiations can…

Neural and Evolutionary Computing · Computer Science 2023-04-11 Robert Tjarko Lange , Tom Schaul , Yutian Chen , Chris Lu , Tom Zahavy , Valentin Dalibard , Sebastian Flennerhag

The paper presents a method for failure free genetic algorithm optimization of a system controller. Genetic algorithms present a powerful tool that facilitates producing near-optimal system controllers. Applied to such methods of…

Neural and Evolutionary Computing · Computer Science 2007-05-23 E. S. Sazonov , D. Del Gobbo , P. Klinkhachorn , R. L. Klein

Model merging, typically on Instruct and Thinking models, has shown remarkable performance for efficient reasoning. In this paper, we systematically revisit the simplest merging method that interpolates two weights directly. Particularly,…

Artificial Intelligence · Computer Science 2026-01-27 Taiqiang Wu , Runming Yang , Tao Liu , Jiahao Wang , Ngai Wong

Machine-learned interatomic potentials (MILPs) are rapidly gaining interest for molecular modeling, as they provide a balance between quantum-mechanical level descriptions of atomic interactions and reasonable computational efficiency.…

Computational Physics · Physics 2024-08-30 Gustavo R. Pérez-Lemus , Yinan Xu , Yezhi Jin , Pablo F. Zubieta Rico , Juan J. de Pablo

In today's economy, it becomes important for Internet platforms to consider the sequential information design problem to align its long term interest with incentives of the gig service providers. This paper proposes a novel model of…

Artificial Intelligence · Computer Science 2022-02-23 Jibang Wu , Zixuan Zhang , Zhe Feng , Zhaoran Wang , Zhuoran Yang , Michael I. Jordan , Haifeng Xu

In this work we are interested in the problems of supervised learning and variable selection when the input-output dependence is described by a nonlinear function depending on a few variables. Our goal is to consider a sparse nonparametric…

Machine Learning · Statistics 2012-08-14 Lorenzo Rosasco , Silvia Villa , Sofia Mosci , Matteo Santoro , Alessandro verri

The effort to understand network systems in increasing detail has resulted in a diversity of methods designed to extract their large-scale structure from data. Unfortunately, many of these methods yield diverging descriptions of the same…

Data Analysis, Statistics and Probability · Physics 2015-03-27 Tiago P. Peixoto

This paper introduces a new probabilistic framework for supervised learning in neural systems. It is designed to model complex, uncertain systems whose random outputs are strongly non-Gaussian given deterministic inputs. The architecture…

Machine Learning · Statistics 2025-12-12 Christian Soize

There is growing consensus among neuroscientists that neural circuits critical for survival are the result of genomic decompression processes. We introduce SynaptoGen, a novel computational framework--member of the Connectome Models…

Neural and Evolutionary Computing · Computer Science 2025-09-09 Tommaso Boccato , Matteo Ferrante , Nicola Toschi

A good representation for arbitrarily complicated data should have the capability of semantic generation, clustering and reconstruction. Previous research has already achieved impressive performance on either one. This paper aims at…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Yuqian Zhou , Kuangxiao Gu , Thomas Huang

A well-trained Convolutional Neural Network can easily be pruned without significant loss of performance. This is because of unnecessary overlap in the features captured by the network's filters. Innovations in network architecture such as…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Aaditya Prakash , James Storer , Dinei Florencio , Cha Zhang

Generative models have the ability to synthesize data points drawn from the data distribution, however, not all generated samples are high quality. In this paper, we propose using a combination of coresets selection methods and ``entropic…

Machine Learning · Computer Science 2023-02-02 Omead Pooladzandi , Pasha Khosravi , Erik Nijkamp , Baharan Mirzasoleiman

This paper discusses a class of thresholding-based iterative selection procedures (TISP) for model selection and shrinkage. People have long before noticed the weakness of the convex $l_1$-constraint (or the soft-thresholding) in wavelets…

Statistics Theory · Mathematics 2009-11-29 Yiyuan She

Deep convolutional neural networks have liberated its extraordinary power on various tasks. However, it is still very challenging to deploy state-of-the-art models into real-world applications due to their high computational complexity. How…

Computer Vision and Pattern Recognition · Computer Science 2018-09-06 Zehao Huang , Naiyan Wang

We propose a new framework for generating cross-sectional synthetic datasets via disjoint generative models. In this paradigm, a dataset is partitioned into disjoint subsets that are supplied to separate instances of generative models. The…

Machine Learning · Computer Science 2025-07-29 Anton Danholt Lautrup , Muhammad Rajabinasab , Tobias Hyrup , Arthur Zimek , Peter Schneider-Kamp