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We describe a new generation of algorithms capable of mapping the structure and conformations of macromolecules and their complexes from large ensembles of heterogeneous snapshots, and demonstrate the feasibility of determining both…

Biological Physics · Physics 2014-04-30 P. Schwander , R. Fung , A. Ourmazd

Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

We propose a novel neural architecture for computer vision -- WaveMix -- that is resource-efficient and yet generalizable and scalable. While using fewer trainable parameters, GPU RAM, and computations, WaveMix networks achieve comparable…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Pranav Jeevan , Kavitha Viswanathan , Anandu A S , Amit Sethi

Artificial intelligence has shown remarkable success in materials discovery and property prediction, particularly for crystalline and polymer systems where material properties and structures are dominated by discrete graph representations.…

Machine Learning · Computer Science 2026-05-20 Xinyao Li , Hangwei Qian , Jingjing Li , Lei Zhu , Ivor Tsang

We propose a novel approach to image classification inspired by complex nonlinear biological visual processing, whereby classical convolutional neural networks (CNNs) are equipped with learnable higher-order convolutions. Our model…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Simone Azeglio , Olivier Marre , Peter Neri , Ulisse Ferrari

The nature of optical metrology is to perform efficient transfer and precise retrieval for lasers and optical signals, which is beneficial for a variety of applications ranging from optical clocking, spectroscopy, to telecommunications and…

Optics · Physics 2025-05-20 Yongyuan Chu , Lu Yang , Wenle Weng , Junqiu Liu , Hairun Guo

Sequence models such as transformers require inputs to be represented as one-dimensional sequences. In vision, this typically involves flattening images using a fixed row-major (raster-scan) order. While full self-attention is…

Machine Learning · Computer Science 2025-10-24 Declan Kutscher , David M. Chan , Yutong Bai , Trevor Darrell , Ritwik Gupta

Optical imaging through complex media, such as biological tissues or fog, is challenging due to light scattering. In the multiple scattering regime, wavefront shaping provides an effective method to retrieve information; it relies on…

Microscopy is a powerful visualization tool in biology, enabling the study of cells, tissues, and the fundamental biological processes; yet, the observed images typically suffer from blur and background noise. In this work, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Valeriya Pronina , Filippos Kokkinos , Dmitry V. Dylov , Stamatios Lefkimmiatis

Ptychography enables coherent diffractive imaging (CDI) of extended samples by raster scanning across the illuminating XUV/X-ray beam thereby generalizing the unique advantages of CDI techniques. Table-top realizations of this method are…

We propose an approach for imaging in scattering media when large and diverse data sets are available. It has two steps. Using a dictionary learning algorithm the first step estimates the true Green's function vectors as columns in an…

Computer Vision and Pattern Recognition · Computer Science 2023-10-23 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

We demonstrate orientation-sensitive multimodal nonlinear optical polarizing microscopy capable of probing orientational, polar, and biaxial features of mesomorphic ordering in soft matter. This technique achieves simultaneous imaging in…

Soft Condensed Matter · Physics 2015-05-19 Taewoo Lee , Rahul P. Trivedi , Ivan I. Smalyukh

We demonstrate an integrated photonic circuit based on feed forward photonic meshes that can be programmed and reconfigured to perform arbitrary spectral filter functions. We investigate a subset of the available filter functions,…

There will be a paradigm shift in chemical and biological research, to be enabled by autonomous, closed-loop, real-time self-directed decision-making experimentation. Spectrum-to-structure correlation, which is to elucidate molecular…

Chemical Physics · Physics 2026-01-21 Xinyu Lu , Hao Ma , Hui Li , Jia Li , Yi Rong , Yuqiang Li , Tong Zhu , Guokun Liu , Bin Ren

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Acoustic-resolution optoacoustic microscopy (AR-OAM) retrieves anatomical and functional contrast from living tissues at depths not reachable with optical microscopy. The imaging performance of AR-OAM has been advanced with image…

Wavelet based algorithms in numerical analysis are similar to other transform methods in that vectors and operators are expanded into a basis and the computations take place in this new system of coordinates. However, due to the recursive…

comp-gas · Physics 2008-02-03 G. Beylkin

The WaveScalar is the first DataFlow Architecture that can efficiently provide the sequential memory semantics required by imperative languages. This work presents an alternative memory ordering mechanism for this architecture, the…

Hardware Architecture · Computer Science 2007-12-10 Leandro A. J. Marzulo , Felipe M. G. França , Vítor Santos Costa

We suggest and implement an approach for the bottom-up description of systems undergoing large-scale structural changes and chemical transformations from dynamic atomically resolved imaging data, where only partial or uncertain data on…

Materials Science · Physics 2021-04-23 Sergei V. Kalinin , Ondrej Dyck , Stephen Jesse , Maxim Ziatdinov

Classical first-order optimization methods for imaging inverse problems scale poorly with image resolution. Wavelet based multilevel strategies can accelerate convergence under strong blur, but their fixed coarse-to-fine schedules lose…

Signal Processing · Electrical Eng. & Systems 2026-03-03 Edgar Desainte-Maréville , Marion Foare , Paulo Gonçalves , Nelly Pustelnik , Elisa Riccietti