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We study the robustness and stability of the yeast cell regulatory network by using a general inhomogeneous discrete model. We find that inhomogeneity, on average, enhances the stability of the biggest attractor of the dynamics and that the…

Molecular Networks · Quantitative Biology 2008-12-12 L. Wardil , J. K. L. da Silva

We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same cell, and the activation of Notch in presence of Delta in…

Discrete Mathematics · Computer Science 2020-07-31 Elisa Tonello , Heike Siebert

We introduce a scalar reduction method for forced or coupled systems with nonlinearities in both heterogeneity and coupling strength. Heterogeneity is formulated as a relatively weak but nonlinear alteration of the vector field(s). The…

Neurons and Cognition · Quantitative Biology 2026-05-07 Youngmin Park

We implement nonlinear anharmonic interaction in the coupled van der Pol oscillators to investigate the quantum synchronization behaviour of the systems. We study the quantum synchronization in two oscillator models, coupled quantum van der…

Quantum Physics · Physics 2022-07-27 Niss Thomas , M. Senthilvelan

We analyze the physical mechanisms leading either to synchronization or to the formation of spatio-temporal patterns in a lattice model of pulse-coupled oscillators. In order to make the system tractable from a mathematical point of view we…

Statistical Mechanics · Physics 2009-10-30 Albert Diaz-Guilera , Conrad J. Perez , Alex Arenas

We consider optimization of linear stability of synchronized states between a pair of weakly coupled limit-cycle oscillators with cross coupling, where different components of state variables of the oscillators are allowed to interact. On…

Adaptation and Self-Organizing Systems · Physics 2017-08-02 Sho Shirasaka , Nobuhiro Watanabe , Yoji Kawamura , Hiroya Nakao

Nonlinear isolated and coupled oscillators are extensively studied as prototypical nonlinear dynamics models. Much attention has been devoted to oscillator synchronization or the lack thereof. Here, we study the synchronization and…

Pattern Formation and Solitons · Physics 2023-01-04 Golan Bel , Boian S. Alexandrov , Alan R. Bishop , Kim Ø. Rasmussen

The control of network-coupled nonlinear dynamical systems is an active area of research in the nonlinear science community. Coupled oscillator networks represent a particularly important family of nonlinear systems, with applications…

Adaptation and Self-Organizing Systems · Physics 2016-08-03 Per Sebastian Skardal , Alex Arenas

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Numerous biological systems exhibit transitions to synchronised oscillations via a population-density-dependant mechanism known as quorum sensing. Here we propose a model system, based on spatially distributed limit-cycle oscillators, that…

Analysis of PDEs · Mathematics 2022-08-22 Carles Tardío Pi , Jorge Castillo Medina , Pablo Padilla Longoria

Researchers have developed hybrid Van der Pol Rayleigh Duffing type oscillators to model human induced forces; however, their analytical framework has largely relied on the Lindstedt Poincare perturbation method, energy balance approaches,…

Adaptation and Self-Organizing Systems · Physics 2026-02-24 Varun Nevash , Prakash Kumar , Chinika Dangi

This paper considers the oscillations modeled by a forced Van der Pol generalized oscillator. These oscillations are described by a nonlinear differential equation of the form $…

Chaotic Dynamics · Physics 2017-09-25 L. A. Hinvi , C. H. Miwadinou , A. V. Monwanou , J. B. Chabi Orou

Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously…

Cell Behavior · Quantitative Biology 2016-08-23 Hiroshi Kori , Yoji Kawamura , Naoki Masuda

We develop a general theoretical framework of semiclassical phase reduction for analyzing synchronization of quantum limit-cycle oscillators. The dynamics of quantum dissipative systems exhibiting limit-cycle oscillations are reduced to a…

Adaptation and Self-Organizing Systems · Physics 2019-10-16 Yuzuru Kato , Naoki Yamamoto , Hiroya Nakao

The phenomenon of slow switching in populations of globally coupled oscillators is discussed. This characteristic collective dynamics, which was first discovered in a particular class of the phase oscillator model, is a result of the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hiroshi Kori , Yoshiki Kuramoto

In this paper, a modified van der Pol oscillator equation is considered which appears in several heart action models. We study its global dynamics and verify many interesting bifurcations such as a Hopf bifurcation, a heteroclinic saddle…

Dynamical Systems · Mathematics 2019-02-01 Ibrahim Jawarneh , Ross Staffeldt

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

We consider two identical oscillators with weak, time delayed coupling. We start with a general system of delay differential equations then reduce it to a phase model. With the assumption of large time delay, the resulting phase model has…

Dynamical Systems · Mathematics 2020-07-15 Isam Al-Darabsah , Sue Ann Campbell

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

We investigate the oscillatory dynamics and bifurcation structure of a reaction-diffusion system with bistable nonlinearity and mass conservation, which was proposed by [Otsuji et al, PLoS Comp. Biol. 3 (2007), e108]. The system is a useful…

Cell Behavior · Quantitative Biology 2025-05-23 Masataka Kuwamura , Hirofumi Izuhara , Shin-ichiro Ei