Related papers: A robust, scalable K-statistic for quantifying imm…
Spherical k-Means is frequently used to cluster document collections because it performs reasonably well in many settings and is computationally efficient. However, the time complexity increases linearly with the number of clusters k, which…
Uniform sampling is a highly efficient method for data summarization. However, its effectiveness in producing coresets for clustering problems is not yet well understood, primarily because it generally does not yield a strong coreset, which…
This paper introduces a novel K-means clustering algorithm, an advancement on the conventional Big-means methodology. The proposed method efficiently integrates parallel processing, stochastic sampling, and competitive optimization to…
In this work, we propose to use a local clustering approach based on the sparse solution technique to study the medical image, especially the lung cancer image classification task. We view images as the vertices in a weighted graph and the…
Reliable quantification of Ki-67, a key proliferation marker in breast cancer, is essential for molecular subtyping and informed treatment planning. Conventional approaches, including visual estimation and manual counting, suffer from…
Single-cell proteomics (SCP) is transforming our understanding of biological complexity by shifting from bulk proteomics, where signals are averaged over thousands of cells, to the proteome analysis of individual cells. This granular…
In this paper, we present a new statistical approach to automatically identify cancer regions in pathological images. The proposed method is built from statistical theory in line with evidence-based medicine. The two core technologies are…
Dynamical evolution drives globular clusters toward core collapse, which strongly shapes their internal properties. Diagnostics of core collapse have so far been based on photometry only, namely on the study of the concentration of the…
Tissues and organs are composed of distinct cell types that must operate in concert to perform physiological functions. Efforts to create high-dimensional biomarker catalogs of these cells are largely based on transcriptomic single-cell…
The Holme-Kim random graph processes is a variant of the Barabasi-Albert scale-free graph that was designed to exhibit clustering. In this paper we show that whether the model does indeed exhibit clustering depends on how we define the…
Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…
Visual thinking plays an important role in scientific reasoning. Based on the research in automating diverse reasoning tasks about dynamical systems, nonlinear controllers, kinematic mechanisms, and fluid motion, we have identified a style…
A standard approach for assessing the performance of partition models is to create synthetic data sets with a prespecified clustering structure, and assess how well the model reveals this structure. A common format is that subjects are…
Clustering non-Euclidean data is difficult, and one of the most used algorithms besides hierarchical clustering is the popular algorithm Partitioning Around Medoids (PAM), also simply referred to as k-medoids clustering. In Euclidean…
This paper presents a kriging method for spatial prediction of temporal intensity functions, for situations where a temporal point process is observed at different spatial locations. Assuming that several replications of the processes are…
In this work, the possibility of clustering correlated random variables was examined, both because of their mutual similarity and because of their similarity to the principal components. The k-means algorithm and spectral algorithms were…
Accurate reconstruction of missing morphological indicators of a city is crucial for urban planning and data-driven analysis. This study presents the spatial-morphological (SM) imputer tool, which combines data-driven morphological…
The Shape Interaction Matrix (SIM) is one of the earliest approaches to performing subspace clustering (i.e., separating points drawn from a union of subspaces). In this paper, we revisit the SIM and reveal its connections to several recent…
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to…
Notwithstanding the popularity of conventional clustering algorithms such as K-means and probabilistic clustering, their clustering results are sensitive to the presence of outliers in the data. Even a few outliers can compromise the…